Dogster is reader-supported. When you buy via links on our site, we may earn a commission at no cost to you. Learn more.

Dog Health & Care

Liver Disease in Dogs: Our Vet Discusses Signs, Causes & Treatments

Dr. Chyrle Bonk
Written and fact-checked by Dr. Chyrle BonkVet Approved
Dr. Chyrle Bonk
Reviewed & Fact-Checked byDr. Chyrle BonkDVM (Veterinarian)
On top of caring for animals and writing for veterinary publications, Dr. Chyrle Bonk owns a small cattle herd! When she’s not busy with those things, she can be found somewhere enjoying the Idaho outdoors with her husband and two kids. Dr. Chyrle Bonk received her Doctor of Veterinary Medicine (DVM) from Oregon State University in 2010.View authorThe information is current and up-to-date in accordance with the latest veterinarian research. Learn more
Updated on June 29, 2026
Share
Female vet examining sick and sad Rhodesian ridgeback dog

The liver is an impressive organ! Not only is it like the body’s oil filter, but it also has the ability to regenerate should it become injured or damaged. However, that doesn’t mean the liver should be left entirely to its own devices. It still needs support during times of need. For example, liver disease can have many possible issues, multiple potential causes, and various often-ambiguous signs.

Here, we look into liver disease in dogs so you can better understand what it looks like, what causes it, and how it can be treated.

divider dog faces oct 2024

What Is Liver Disease in Dogs?

The liver screens the blood to remove toxins and other substances that are then excreted from the body. It also breaks down specific things, such as certain medications, and serves as storage for vitamins and glycogen for energy. In addition, it produces bile that helps in digestion.

Liver disease is an umbrella term for many potential issues that plague the liver and cause inflammation or even damage to or the death of the liver cells. Since the liver does so many different jobs, things that bother it can vary greatly in signs, depending on the pathways that they are affecting. This sometimes makes it difficult to diagnose liver disease and pinpoint an exact cause. Knowing what is normal for your dog will help you recognize when something isn’t quite right so you can alert your veterinarian of the signs as soon as possible.

Image Credit: Jaromir Chalabala, Shutterstock

What Are the Signs of Liver Disease in Dogs?

Liver disease in dogs can be vague, especially in the beginning, producing signs like:

  • Lethargy
  • Decreased appetite
  • Vomiting
  • Diarrhea
  • Increased drinking/increased peeing
  • Weight loss

More specific signs include:

  • Jaundice: The liver removes bilirubin, a yellowish pigment that is a byproduct of red blood cell breakdown. If the liver isn’t working to full capacity, bilirubin can build up in the body, causing a yellowing of the skin and mucous membranes, most noticeable in the eyes, gums, and ears.
  • Ascites: Damage to the liver can increase the blood pressure in the portal vein, which carries blood to the liver. If the pressure is high enough, fluid will leak from the vessels and collect in the abdomen, creating an enlarged belly full of fluid.
  • Hepatic encephalopathy: If certain toxins aren’t removed from the blood, they can cause neurological issues, including incoordination, behavioral changes, head pressing, or seizures.
  • Gray or yellow poop

Signs may show up suddenly or gradually and tend to get worse if untreated.

Image Credit: Daria Lixovetckay, Shutterstock

What Are the Causes of Liver Disease in Dogs?

The causes of liver disease are as numerous and varied as the functions of the organ itself.

Congenital Defects

Before birth, the liver isn’t truly necessary. Instead, the mother dog’s liver does all the filtering, so the puppy’s liver remains unhooked until birth. Blood bypasses it via a shunt. When a puppy is born, that shunt is supposed to close, enabling blood through the liver. Occasionally, though, that shunt doesn’t close, meaning some or all the blood bypasses the liver without being filtered, creating problems. Older dogs can also develop (acquire) shunts related to severe scarring of the liver or blood clots .

Infections

Being the filter of the body means the liver encounters nearly everything, including all the nasties that can make the body sick. Sometimes it can become infected itself with different types of viruses, bacteria, or fungi. Adenovirus, leptospirosis, and histoplasmosis are a few common culprits.

Toxins

Part of the liver’s job is to filter toxins so they don’t damage the rest of the body, making it seem immune to intoxication. However, there are toxins out there that target a dog’s liver. One of the most commonly known ones is xylitol, the sweetener used in many human products. Also on the list are specific medications, plants, foods, and chemicals.

Image Credit: morisfoto, Shutterstock

Tumors

The liver can develop cysts and masses that can cause signs of liver disease if they’re large or numerous. It can also develop cancer. Cancer in the liver can come from the liver cells themselves or more commonly, from somewhere else in the body. Due to its blood-filtering role, tumor cells from other areas of the body commonly end up in the liver.

Storage Diseases

The liver serves as storage for many helpful ingredients, including vitamins and glycogen. Sometimes, though, it can also store things in an unhealthy way. Certain breeds are prone to liver disease that includes excessive storage of copper or amyloidosis, which is the buildup of abnormal proteins.

Others

Whole body issues, such as diabetes, Cushing’s disease, and thyroid issues, can also affect the liver’s function.

If you are concerned about the health and well-being of your pet, seek veterinary advice for the best course of action.

divider dog faces oct 2024

How Do I Care for a Dog With Liver Disease?

Liver disease can look like many other things, especially in the early stages, so you should see a vet if you start to notice that something is off with your pup. The veterinarian will do an exam that may unveil or explain the more tell-tale signs of liver disease, like jaundice or an enlarged abdomen, and they may run further diagnostic tests. Blood work and imaging may further point to liver issues, while a biopsy may be necessary to find the underlying cause of the problem.

Even though the liver has the ability to regenerate, starting treatment as early as possible is imperative. Although regeneration is indeed a superpower, it can’t save a severely damaged liver, so it’s crucial to get a handle on the problem before it worsens.

Depending on the cause, treatment for the liver typically involves a great deal of support. Things like changing diets and adding supplements and vitamins can help encourage liver health. Antibiotics or antifungals may be needed for an infection, while surgery and/or chemotherapy and radiation may be needed for cancer.

A dog with liver disease will also require further monitoring to ensure that their liver is regaining function. They may also require repeated blood tests or imaging even as they start to get better.

Keeping your dog up to date on their vaccinations is an essential step in preventing liver disease, as a few of the most common causes of liver infections can be vaccinated against.

Image Credit: hedgehog94, Shutterstock
divider single dog paw oct 2024

Frequently Asked Questions (FAQ)

How Long Can a Dog Live With Liver Disease?

Dogs with some types of liver disease will get better within a couple of days to a few weeks, especially if it’s caught and treated early. Other types will take a couple of weeks to a few months, and some dogs won’t recover at all, living for only a few weeks or months after diagnosis. It’s so highly variable that a specific answer can’t be provided for this question. Instead, discuss your dog’s specific issues with your vet.

Can a Dog Recover From Liver Damage?

Whether the liver can recover from damage depends on what caused the damage and how much there is. Minor damage from inflammation related to a mild infection will often clear up within a week or so with proper treatment, while major damage from cancer or a chronic disease might be too deleterious to come back from.

What Should You Not Feed a Dog With Liver Problems?

Cutting back on protein can help liver function, as it decreases the number of certain byproducts to filter from the blood. This means high-protein diets or those with large amounts of red meat should be avoided. You may also need to avoid copper or salt in certain cases and cut out fatty or sugary foods, such as table scraps and other human foods. Your vet will recommend a diet specific to your dog’s issues.

Image Credit: SeventyFour, Shutterstock
divider dog faces oct 2024

Conclusion

The liver is a major multitasker organ, which makes it incredibly useful in a dog’s body. However, wearing so many hats makes it susceptible to a variety of different issues.

Liver disease is when the liver cells get inflamed or damaged due to an infection, toxin, cancer, or another whole-body issue. The early signs can be subtle, so getting veterinary care as soon as you suspect that something is off with your dog is vital in order to get quick and proper treatment.

Sources

Featured Image Credit: Zontica, Shutterstock

The Dogster Newsletter

Expert dog care, straight to your inbox

News, insights, expert advice, and everything dog.

No spam — unsubscribe anytime.

By signing up, you agree to our Terms & Conditions and Privacy & Cookies Policy.

Click a star to rate. You can leave written feedback afterwards. (We read all feedback.)

Dr. Chyrle Bonk DVM (Veterinarian)
Authored by

Dr. Chyrle Bonk DVM (Veterinarian)

8 Common Liver Problems in Dogs: Our Vet Explains

8 Common Liver Problems in Dogs: Our Vet Explains

Liver enzyme elevations are common in blood tests, whether your dog is unwell or just receiving pre-anesthetic blood work. You might be familiar with the “ALT”…

Dr. Ashley Darby
By Dr. Ashley Darby · 2 weeks ago
Chronic Hepatitis In Dogs: Our Vet Discusses Signs, Causes & Treatment

Chronic Hepatitis In Dogs: Our Vet Discusses Signs, Causes & Treatment

If your dog has been struggling with liver issues, you are doing the right thing by learning as much as possible about it. If they’ve had liver biopsies, they…

Dr. Ashley Darby
By Dr. Ashley Darby · 2 weeks ago
High Liver Enzymes in Dogs: What it Means and What to Do (Vet Answer)

High Liver Enzymes in Dogs: What it Means and What to Do (Vet Answer)

What do elevated liver enzymes in dogs indicate? And why are elevated liver enzymes in dogs sometimes baffling — even for your vet?

Dr. Kim Podlecki
By Dr. Kim Podlecki · 2 weeks ago
Can Dog Food Cause Elevated Liver Enzymes? Vet Approved Info

Can Dog Food Cause Elevated Liver Enzymes? Vet Approved Info

Blood tests provide a great gauge of your dog's overall internal health. If you’ve recently had blood testing done and are curious about your dog’s high liver…

Chantelle Fowler
By Chantelle Fowler · 3 weeks ago

Yellow Dog Poop: Meaning & When to Worry (Vet Answer)

Have you noticed your dog’s poop has suddenly turned yellow? Are you wondering if you need to be worried or not? This vet-written guide will give you all the i…

Dr. Emma Chandley BVM
By Dr. Emma Chandley BVM · June 17, 2026
Yellow Dog Poop: Meaning & When to Worry (Vet Answer)

Why Is My Dog Throwing Up Bile? Vet-Reviewed Causes & Treatments

It’s a fact of life that your dog is going to vomit at some point. It is often just the regurgitation of their food because they ate it too quickly, but someti…

Kathryn Copeland
By Kathryn Copeland · June 29, 2026
Why Is My Dog Throwing Up Bile? Vet-Reviewed Causes & Treatments

Why You Should Never Ignore Yellow Dog Poop

Yellow dog poop is one of those things that sounds bizarre until it happens to your dog. Then suddenly you're standing there with a poop bag in hand, staring a…

Dan Seymour
By Dan Seymour · June 16, 2026
Why You Should Never Ignore Yellow Dog Poop

10 Vet-Verified Signs That Your Dog Is Sick & What to Do

When our dogs are sick, it is essential to seek out veterinarian care quickly. Many illnesses can be treated inexpensively and easily if they are caught early.…

Nicole Cosgrove
By Nicole Cosgrove · June 29, 2026
10 Vet-Verified Signs That Your Dog Is Sick & What to Do

11 Most Common Diseases, Illnesses & Health Risks in Dogs

If you recently purchased a new puppy or are considering getting a dog for your family, it’s common to wonder what the most common diseases might be so you can…

Nicole Cosgrove
By Nicole Cosgrove · June 29, 2026
11 Most Common Diseases, Illnesses & Health Risks in Dogs

Kidney Failure in Dogs: Signs, Care & Treatment Options

The kidneys serve vital functions in your dog’s health. They help to eradicate dangerous toxins that build up in your dog’s body from normal cell function. Mor…

Dean Eby
By Dean Eby · June 29, 2026
Kidney Failure in Dogs: Signs, Care & Treatment Options

Dog Skin Discoloration: Vet-Reviewed Causes & Treatment

Many of us don’t regularly see the majority of our dog’s skin because of their fur coat. You may get a glimpse at your dog’s skin on their face, ears, and bell…

Brooke Billingsley
By Brooke Billingsley · June 17, 2026
Dog Skin Discoloration: Vet-Reviewed Causes & Treatment

How to Make Dog Treats That Are Actually Healthy

You're scanning dog treat ingredient lists at the grocery store when you notice a pattern: chicken, rice, sweet potato, mystery "byproducts." Then you see the…

Dan Seymour
By Dan Seymour · June 16, 2026
How to Make Dog Treats That Are Actually Healthy

Love Dogs? So Do We! Join the Dogster Community

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.

You may opt-out at any time. View our Privacy Policy for more information.

The Dogster app on a phone