Hyaflex™ PRO Complete Joint Care Liquid Review 2025: Our Hands-On Test

When it comes to protecting your aging dog’s joints, you probably already know all about glucosamine and MSM. But did you know that there is more you can do to keep those old joints in top shape?

Hyaluronic acid is an important but lesser-known factor in joint health. Unfortunately, as dogs age, their bodies produce less and less of this substance. This is exactly why Hyalogic uses it as a base for their joint health supplements.

Their unique Hyaflex™ PRO Complete Joint Care Liquid contains this important compound as well as glucosamine and MSM for all-around better joint health. My two senior dogs have been testing this supplement for the last three weeks and I have already seen some pretty surprising results.

Keep reading to find out how this hyaluronic acid supplement has helped them and to see my full Hyalogic Hyaflex™ PRO Complete Joint Care Liquid review.

Overview

Our Experience

As the owner of two senior dogs, I am very familiar with the importance of joint support. My Dalmatian mix, Ragz, turns fourteen this month and has dealt with a bum shoulder since she was a youngster. My fifteen-year-old Chihuahua, Papyrus, is even worse off, with lifelong double luxating patellas that have left his whole backend sore and stiff.

Both of them have been on a glucosamine supplement for years. Thanks to those supplements and CBD, they get around fairly well with minimal pain. Still, I felt there was more I could do to support their joint health and prevent further damage.

That’s why I jumped at the opportunity to test Hyaflex™ PRO Complete Joint Care Liquid from Hyalogic. This unique joint supplement contains hyaluronic acid (HA), a compound that supports joint, eye, and skin health. I had never used HA for my dogs before and was excited to see how this supplement might help them.

What I Liked

This joint supplement is different from most in many ways. For one, it is a clear, viscous liquid. This makes it fairly easy to administer. I added a dose to each of my dogs’ breakfasts every day and they had no problem eating it up.

The easy dose bottle makes this process simple and prevents the mess that most liquid supplements leave behind.

I also like how pure the ingredients are. Each bottle contains HA, Glucosamine, MSM, water, and zinc citrate. There are no artificial colors, synthetic preservatives, or added flavors.

Of course, the most important aspect of any supplement is how well it works. Here, I was very impressed. It took a couple of weeks to see results, but once the changes started rolling in, I was amazed.

Ragz has always done fairly well on a simple glucosamine supplement, but nothing has been able to improve Papyrus’ backend mobility issues. But after two weeks of consistent use, his knees and hips started moving like they used to.

He still has the occasional hitch in his step from his luxating patellas, but the range of motion in his hips has improved drastically. At the same time, the pain in his lower back seems to have lessened, probably because the muscles in his back legs are less tense due to decreased joint pain.

Both dogs seem less stiff and are able to get up and down easier than before. All indications are that this supplement has provided more joint pain relief and lubrication than the glucosamine-based supplements I was using before.

Where I Saw Room for Improvement

One minor gripe I have about this product is that the easy-measure bottle doesn’t have markings for ⅛ oz servings. Rather, the instructions say to use the cap to measure out the doses (1/2 cap for small dogs and 1 cap for large dogs). But, because pouring straight from the measuring reservoir is so much less messy, I usually just eyeball Papyrus’ small dog dose.

In terms of more substantial issues, I think it is important to note that the amounts of glucosamine and MSM in this supplement are pretty small. Each large dog dose contains only 75mg of each. Since the recommended dose of MSM is 50 to 100mg per 10 pounds and the recommended glucosamine dose is even higher, this supplement doesn’t quite provide enough of each on its own.

However, I did still see substantial improvements in my dogs’ mobility while using this supplement. This tells me that the lubricating activity of HA is doing more in the short term for their joint health than glucosamine and MSM. To get the best of both worlds, I am going to add a separate glucosamine, MSM, and chondroitin supplement on top of this with the hopes that I will see sustained improvement for the long term.

Pros & Cons

Key Features

Contains Hyaluronic Acid

Research has shown that the amount of hyaluronic acid present in the space between joints decreases with age and joint disease severity (source). Because this compound is vital for lubricating joints, decreased amounts can lead to joint damage, inflammation, and pain.

Both injected and orally administrated HA have proven abilities to increase HA fluid concentration around joints and improve mobility (source). Each dose of Hyaflex™ PRO Complete Joint Care Liquid contains 25mg of HA to help keep aging and overworked joints lubricated to avoid damage and inflammation.

How to Administer

Hyaflex™ PRO Complete Joint Care Liquid is a tasteless, odorless liquid, making it super simple to give to your dog. The easiest way to administer this product is to add it to your dog’s meals. Even the pickiest of eaters isn’t likely to notice it.

You can also dose this liquid directly into your dog’s mouth. I tried both methods and had success with each. However, adding it to their food was much easier and less messy.

When to Use

Hyaluronic acid supplementation is key to keeping joints lubricated as dogs age. Hyalogic recommends starting dogs on the supplement around the age of seven. Larger breeds that experience more joint stress should start the product even earlier.

In addition to senior dogs, working dogs and those recovering from stress or injury will also benefit from the supportive effects of HA.

In addition to supporting joint health, this product also lubricates the eyes and skin. This makes it a great option for dogs who suffer from dry eyes, dandruff, or itchiness.

About Hyalogic

Hyalogic makes a wide selection of HA products for both humans and pets.

Is Hyaflex™ PRO Complete Joint Care Liquid a Good Value?

There aren’t a ton of HA-based pet supplements on the market. And the options out there do not contain the added benefits of glucosamine and MSM or the quality guarantee that Hyalogic offers.

So, while this product may be more expensive dose for dose than other HA options, we believe it is still a better value for what you get.

How We Tested

I enlisted the help of my two senior dogs to test this product. I started by taking them off their normal joint support supplement and using HyaFlex Pro in its place.

I administered the liquid directly into their mouths and by adding it to their food to get a feel for its ease of use. While my dogs accepted both methods, adding it to their meals was a much easier option. Going forward, I added the appropriate dose to their breakfasts each morning.

I kept notes about their mobility, stiffness levels, and pain throughout the three-week testing period. At about the two-week point, I noticed a marked improvement in Papyrus’ hip mobility, followed shortly by a clear pain and stiffness reduction in his back end. At the three-week mark, there was a notable improvement in stiffness and activity levels for both dogs.

Additionally, I spent time reading research papers about HA use in pets and diving into the specifics of what makes Hyalogic different from other joint supplement options.

Frequently Asked Questions (FAQ)

How does Hyaflex support joints?

Hyaflex™ PRO Complete Joint Care Liquid helps increase lubrication between joints to prevent damage and relieve inflammation.

Can I give this to my dog before they show signs of joint problems?

Yes. Hyaluronic acid concentrations diminish as our pets age and with increased stress on joints. Supplementing with this product can help support normal HA levels before damage occurs.

What is the dose of Hyaflex™ PRO Complete Joint Care Liquid?

Dogs under 25 pounds should get ⅛ ounce and dogs over 25 pounds should be given ¼ ounce. This dose should be given once per day.

Conclusion

If you’re like me and want to do more to protect your aging dog’s joints, I highly recommend adding Hyaflex™ PRO Complete Joint Care Liquid to their routine.

This unique supplement helps lubricate joints to prevent damage and reduce inflammation that may already be present. It contains MSM and glucosamine to support long-term joint health. And, best of all, it’s easy to dose and produces fast results.