Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Which Dog Vaccines Are Absolutely Necessary? Our Vet Discusses 5 Essential Shots

golden retriever getting a vaccine

Bringing home a new puppy involves a few trips to the veterinarian. Of course, this is a good chance to discuss all aspects of canine health, including diet, worming, exercise, and training. One important part of puppy vet visits is vaccinations. You’re probably aware that puppies need vaccinations.

However, many people do not know what diseases we’re protecting puppies against, and how important it is to do so. Words like C3, DHP, kennel cough, and more get thrown around. But which dog vaccines are absolutely necessary?  Read on to find out!

divider single dog paw oct 2024

The 5 Essential Dog Vaccines

1. Distemper

Canine distemper is a serious and life-threatening disease caused by the distemper virus. This virus is spread by exposure to airborne viral particles from an infected dog; it then attacks the respiratory, gastrointestinal, and nervous systems of dogs. Fever, coughing, loss of appetite, vomiting, and diarrhea are common.

If the nervous system is involved, muscle twitches, head tilts, and seizures can occur. Thankfully, there is a highly effective and very safe vaccination that can prevent puppies from getting infected.

black dachshund getting a vaccine
Image Credit: Masarik, Shutterstock

2. Hepatitis

Hepatitis is defined as inflammation of the liver. In dogs, this is caused by a member of the adenovirus family. In severe cases, as is often the case in puppies, affected dogs experience fever, depression, loss of appetite, vomiting, diarrhea, and abdominal pain. Some dogs develop edema (fluid swellings) and jaundice (yellow discoloration of the gums).

As with the Distemper virus, vaccination has been very successful at both preventing and reducing the prevalence of hepatitis disease.


3. Parvovirus

Canine parvovirus is a highly contagious viral disease of dogs. It affects puppies more commonly and more severely than adult dogs, causing acute (sudden) gastrointestinal illness. Canine parvovirus can be found in almost any environment. Once ingested, the virus makes its way into rapidly dividing cells, such as those of the bone marrow and the lining of the small intestine.

This results in malaise, fever, and loss of appetite. Almost all dogs experience diarrhea; it is often bloody and foul-smelling. Generally speaking, hospitalization and aggressive treatment are needed. Vaccination of puppies against parvovirus is imperative.

Canine distemper, hepatitis, and parvovirus vaccinations are usually combined into one, meaning they are given as a single injection (followed by follow-up “booster” injections). You might hear this single injection referred to as a “core”, “C3” or “DHP” vaccination.

Puppy Vaccine
Image Credit: gorillaimages, Shutterstock

4.  Rabies

Rabies is a deadly disease of many mammalian species, including dogs. This virus is spread through the saliva of infected animals, causing acute and progressive encephalitis (inflammation of the brain). Initially, dogs show vague signs and behavioral changes. Next, they become vicious and behave erratically. Towards the end of the disease process, dogs become weak and paralyzed.

Veterinarians are legally required to vaccinate dogs against rabies in most U.S. states. Widespread vaccination against rabies has dramatically reduced the occurrence of this disease, and ongoing diligent vaccination is essential.


5. Parainfluenza

We’ll preface this by saying that parainfluenza is not technically an essential vaccination, as was the case with 1 through 4. However, veterinarians are routinely vaccinating dogs against the parainfluenza virus to reduce the occurrence and severity of respiratory infection, sometimes referred to as “kennel cough”.

Parainfluenza infection causes a dry, harsh cough, as well as fever and nasal discharge. Infection significantly increases the risk of secondary bacterial infections. Additionally, any dog that is attending a boarding kennel or dog daycare center is required to be vaccinated against parainfluenza.

Cute Labrador puppy getting a vaccine
Image Credit: ARVD73, Shutterstock

divider dog paws oct 2024

Non-Core Dog Vaccines

Beyond the five vaccinations discussed above, other vaccines are just as essential for some dogs, depending on their location, lifestyle, and risk. These “non-core” or “optional” vaccinations are generally administered on a case-by-case basis, and should be considered with a veterinarian:

  • Leptospira
  • Lyme disease
  • Bordetella
  • Rattlesnake toxoid

Consult with a Vet

If you have further concerns about which vaccines are best for your dog, we suggest consulting with a vet for advice.

Did you know you can talk to a vet online? Click on the image or button below to schedule a call: PangoVet_Mention-in-Content Savings V1


divider dog faces oct 2024

Puppy Vaccination Schedule

Your puppy’s vaccination schedule should be discussed with your veterinarian. While not “set in stone”, there are good guidelines for the age at which each vaccination should be given. The first core vaccination is generally given at 8 weeks of age. The second (“booster”) is given a month later, at 12 weeks of age, and the final vaccination is given a month after this, at 16 weeks of age.

In some instances, the first vaccination may be given earlier, and the last later. The adult vaccination schedule begins one year after the last puppy vaccinations. New guidelines suggest that most core vaccines are effective and protective for 3 years, and so they should be given every 3 years, for life.

divider dog paws 3 oct 2024

Conclusion

Don’t underestimate the importance of puppy vaccinations. They prevent your new canine friend from contracting several serious, potentially fatal diseases. The core or essential vaccinations comprise the Distemper virus, Hepatitis virus, Parvovirus, and Rabies virus. While Parainfluenza vaccination is not essential, it is widely performed.

Other vaccinations, such as Leptospira, should be considered in conjunction with your veterinarian, based on your puppy’s level of risk. Most puppies require a course of at least three core vaccinations. It’s natural to have questions about the effectiveness, safety, and side effects of these vaccinations; we recommend discussing these concerns with your veterinarian during your consultation.

See Also:


Featured Image Credit: Ground Picture, Shutterstock

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Ask Dr. Paola- Euthanasia, Lip Licking & Burping (January 27, 2025)

Welcome to our “Ask Dr. Paola” series, where every Monday we bring expert advice straight from Dr. Paola Cuevas (MVZ) to help our...

Do Dogs Have Chakras? Interesting Facts & FAQ

Chakras have their roots in Buddhism and Hinduism. The term describes focal points someone can use in meditative practices to tap into these...

When Will My Golden Retriever Stop Teething? How to Help & Training Tips

Golden Retrievers are intelligent, friendly, and adorable giants who make amazing family pets. But before they turn into the big, lovable dogs we...

Morkie (Maltese & Yorkie Mix): Info, Pictures, Care & Traits

The Morkie is an increasingly popular mixed breed due to their attractive appearance, small size, and hypoallergenic coat, as they make a great...

More related

Why Are Black Dogs Less Likely to Be Adopted? Vet-Verified Facts & How You Can Help

Have you ever heard that black dogs are less adoptable than other colors? It doesn’t just stop with dogs. Cats fall under the...

What Is a Sploot? 3 Theories Why Cats & Dogs Do It

Some of the most popular searches in recent Internet history involve cute pets, especially cats and dogs. One of the newer adorable pet...

What Breed Is the Dog From Coco? The Fascinating Mexican Breed

If you have ever watched Disney’s and Pixar’s movie dubbed Coco, you are likely to have been intrigued by the charming, yet unique...

Can Dogs Have Bed Bugs? Vet-Approved Facts & FAQ

Between the threat of ticks and fleas, dogs seem like natural traps for countless parasitic creepy pests. Fortunately, there’s one common household nuisance...

Keep reading

8 Best Dog Foods for American Staffordshire Terriers in 2025 – Reviews & Top Picks

The American Staffordshire Terrier is a medium-sized dog breed that will benefit from wet or dry dog food rich in lean meats. This muscular dog breed needs a well-balanced diet to meet their nutritional requirements while providing them with the...

Pit bull American Staffordshire Terrier with food bowl eating

What Is Human-Grade Dog Food? Vet-Verified Facts About Ingredient Difference

Bringing a dog into your life is a special time for a family. Not only do you have a new friend, ally, and snuggle partner, but there is also another life you’re responsible for. This means ensuring your pets are...

The farmer's dog Turkey recipe fresh

10 Best Dog Foods for Yeast Infections in 2025 – Reviews & Top Picks

Dogs can suffer from yeast infections similar to humans. Dogs, regardless of their gender, breed, or age can develop a yeast infection at some point due to certain sensitivities, allergies, or a diet high in carbs or sugar. If your...

Labrador dog eating

Can Dogs Eat Chayote? Vet-Verified Facts & FAQ

Chayote (or mirliton/choko) is a fruit that belongs to the gourd family and was first cultivated in Mexico and Honduras. These fruits are a great snack for dogs; they can eat them without any issues. Chayote is nutritious and versatile,...

Can Dogs Eat_chayote

Open Farm Dog Food Review 2025: Our Vet-Approved Expert’s Opinion

If you’re looking for high-quality, human-grade dog food made with locally and sustainably sourced ingredients, then Open Farm may be the answer. This family-owned company arose out of a couple’s desire to feed their dog a nutritious meal made with...

Dogster_Open Farm Dog Food Review

10 Best Stainless-Steel Dog Bowls in 2025 – Reviews & Top Picks

There are many different dog food bowls, but stainless-steel bowls are some of the best options for many dogs. They’re more durable than other materials and can also be more hygienic. There isn’t much variety in stainless steel bowls, but...

two fluffy dogs eating from the triple stainless steel feeders

Can Dogs Eat Daikon? Vet-Approved Facts & FAQ

As daikon radishes gain popularity in human cuisine, it’s only natural for dog owners to wonder if it’s safe to share this sweet and crunchy vegetable with their pups. The short answer is yes, dogs can eat daikon—not only is...

Can Dogs Eat Daikon

Can Dogs Eat Millet? Vet-Verified Benefits & Potential Risks

As a dog owner, it’s important to know what foods are safe for your dog to eat. This is especially true if your pooch is one of those that enjoys begging or sharing what you’re eating. When you’re eating healthy...

Can Dogs Eat_Millet