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How to Get Dog Vomit Out of Mattress: 5 Ideas & Tips (With Pictures)

Genevieve Dugal
By Genevieve DugalUpdated on June 16, 2026
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puppy sitting near wet spot on bed

Like any dog lover, you love your pooch madly and accept that occasional accidents around the house are inevitable. However, if your pup is suddenly sick on your cozy bed, you must act quickly to prevent the foul odor from seeping into the fibers of your mattress.

Check out our five ideas and tricks to effectively remove dog vomit from your mattress so that you can fall back into the arms of Morpheus without being bothered by horrid hints of puke.

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Before You Begin: Gather the Essential Tools

  • Rubber gloves
  • Clean cloth or paper towels
  • Spatula and/or plastic bag
  • Detergent
  • White vinegar
  • Rubbing alcohol
  • Baking soda
  • Enzymatic cleaner
  • Spray bottle

Effective cleaning starts with having the essentials on hand. Most homes are equipped with the supplies above, but the one many people may not have or realize they need until it's too late is a pet-friendly enzyme cleaner. These active cleaners were created to break down the compounds in animal messes that cause staining and lingering odors. Being proactive and keeping a bottle on hand will save you from scrambling in a pinch.

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Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray is our favorite all-purpose cleaner for pet messes. It permanently lifts the very worst stains and odors, making clean-up and accident prevention a breeze. Hepper offers a 100% guarantee, which is a great bonus! Learn more about it here.

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The 5 Ideas & Tips on How to Get Dog Vomit Out of Mattress

1.  Remove Any Vomit Residue

Image Credit: TFEX_SHUTTER, Shutterstock

The first step is to remove all the dog vomit that is on your mattress. Use a spatula or a plastic bag and get rid of all traces of vomit. Then, dispose of the bag and its contents immediately.

Note: Wear disposable gloves to avoid contact with germs or other bacteria that may be in the vomit.


2. Throw All Bedding in the Washing Machine

Image By: agencies, Shutterstock

It doesn't matter if your dog spilled his stomach contents on your sheets or not, put everything in the washing machine. This includes sheets, duvets, blankets, pillowcases, etc. Wash the bedding at the highest temperature possible to eliminate odors and germs.


3. Clean Your Mattress Thoroughly

Image By: Olga Aniven, Shutterstock

Mix warm water and a mild detergent in a container. Soak the soiled area with soapy water and dab with a clean cloth.

Fill a spray bottle with one part water and three parts white vinegar. Spray the area liberally with the diluted vinegar solution, which will help disinfect and deodorize the soiled area. Let dry and repeat the treatment with vinegar if the stain persists.


4. Use Rubbing Alcohol to Disinfect

Image Credit: Squirrel_Photos, Pixabay

Even if the vomit stain is no longer visible after the previous steps, germs and a slight smell of vomit may still be present. Fill your spray bottle with rubbing alcohol and spray the entire mattress.


5. Ventilate the Room

Photo credit: StockSnap, Pixabay

Use a fan and open all windows to help your mattress dry quickly and eliminate any lasting odor.

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Other Tips for Getting the Dog Vomit Smell Out of Your Mattress

  • Sprinkle Baking Soda on the Stain: Baking soda is as versatile in its uses as white vinegar! So, after blotting the soiled area, sprinkle a generous amount of baking soda to help absorb any residual liquid and eliminate the foul odor.
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Conclusion

The solutions presented above are effective and safe for you, your dog, and your mattress. Plus, they don't just apply to your puppy's vomit: if it's you or a loved one who got sick in bed, know that you can use the same methods without a problem. However, keep in mind that these solutions are not miraculous for old vomit stains. In this case, you will probably need to hire a professional cleaner to remove the nasty residual stains and odors.

You may also be interested in:


Featured Image Credit: cunaplus, Shutterstock

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Genevieve Dugal
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