Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

8 Common Puppy Illnesses & Diseases to Be Aware Of

cheerful young veterinary taking care and examining a beautiful pet dog french bulldog.

Puppies have so much growing up to do! Part of that process involves developing a healthy and strong immune system. As puppies age, they start to lose the protective antibodies that they acquired from their mother and begin to develop their own immune defenses.

However, this transition can make them vulnerable to sickness, especially those that aren’t fully vaccinated. The following list highlights the common illnesses and diseases that puppies can acquire.

divider dog paws 4 oct 2024

The 8 Common Puppy Illnesses & Diseases to Be Aware Of

1. Parvovirus (Parvo)

Parvovirus attacks the gastrointestinal system and causes signs like vomiting, bloody diarrhea, lethargy, anorexia, and dehydration. The virus is transmitted through contaminated feces, is highly contagious, and can prove fatal. The virus is also hardy in the environment and may survive for months or years. Ideally, puppies diagnosed with parvo should be hospitalized, as there is no cure for the disease, only supportive care.

mixed breed puppy with parvovirosis at the veterinary clinic
Image Credit: Todorean-Gabriel, Shutterstock

2. Distemper

Like parvo, distemper is a highly contagious and often fatal virus. It can attack the nervous, gastrointestinal, and respiratory systems, producing signs like seizures, head tilt, circling, fever, lethargy, coughing, and discharge from the eyes and nose. Some puppies develop thickened paw pads and may have dental abnormalities if they survive the disease. Other puppies may have neurological abnormalities that persist for life. Distemper virus can be transmitted in respiratory droplets from sneezing or coughing or from contaminated food and water bowls. There’s no cure but there is supportive care.


3. Canine Infectious Respiratory Disease (Kennel Cough)

Canine infectious respiratory disease is a common and easily transmissible respiratory virus among dogs. It may be caused by bacteria (like Bordetella bronchiseptica), a virus (like canine parainfluenza virus or canine coronavirus), or both. Most infections resolve on their own in 1–3 weeks, while more severe signs may require treatment like antibiotics, an anti-inflammatory, and a cough suppressant from your veterinarian. Severe cases of kennel cough may lead to pneumonia.

If your puppy is diagnosed with kennel cough, use a body harness instead of a collar so the pressure does not irritate their trachea.

Brindle Cane Corso standing on a grass field outdoors while wearing a harness
Image Credit: Eudyptula, Shutterstock

4. Leptospirosis

Leptospirosis is an infection caused by bacteria (Leptospira) that are shed through infected urine. It can be transmitted in contaminated water sources that are visited by wildlife and livestock, soil, bedding, or any surface containing infected urine. The infection attacks the kidneys and liver and is typically treated with antibiotics and aggressive fluid therapy in more severe cases.

Despite treatment, the disease can be fatal. It is also contagious to humans, making it a zoonotic disease. Care must be taken around puppies and dogs diagnosed with leptospirosis to avoid catching it. This includes wearing disposable gloves and washing your hands after cleaning up after your dog.


5. Adenovirus

Adenovirus is a virus that causes infectious canine hepatitis in puppies and dogs. It usually attacks the liver and is spread through contact with an infected animal or surface. Signs may include lethargy, inappetence, fever, vomiting, and diarrhea. There’s no cure, only supportive care. Unfortunately, the survival rate is low, only 1–30%.

sick weakened puppy lies in the arms of owner
Image Credit: Gladskikh Tatiana, Shutterstock

6. Rabies

Rabies is always fatal once clinical signs develop. This deadly virus is shed in saliva and transmitted through the bite of an infected animal. The signs may include behavioral changes, neurological abnormalities, hyperexcitability, or paralysis. Rabies is also contagious for humans, so if you’ve been bitten or scratched by a strange dog, you must seek medical care immediately.


7. Parasites

Internal and external parasites can affect puppies. Common internal parasites include roundworms, hookworms, stomach worms, tapeworms, giardia, coccidia, and heartworms. External parasites include fleas, ticks, mites, and lice.

owner applying flea and tick medicine to a dog
Image Credit: Nick Alias, Shutterstock

8. Vomiting and Diarrhea

Vomiting and diarrhea in a puppy can be caused by several underlying conditions that a veterinarian should evaluate. Common conditions include foreign bodies, toxins, stress, sudden diet changes, or bacterial, viral, or parasitic-related illnesses.

Dogster_Website dividers_v1_Jan 18 2024-03

How Can I Keep My Puppy Safe?

Start with the core vaccinations, such as DA2PPv, when your puppy reaches 6–8 weeks old.

This combination vaccine includes:
  • Distemper virus
  • Adenovirus type 2
    • This cross-protects against Adenovirus type 1, which causes infectious canine hepatitis; type 2 causes tracheobronchitis.
  • Parainfluenza (tracheobronchitis)
  • Parvovirus

To provide the best protection, it’s administered every 2–4 weeks until your puppy is 16–20 weeks old.

Another vaccine to consider is the one for canine infectious respiratory disease, especially the one caused by the bacterium Bordetella bronchiseptica. Puppies can get this starting at 8 weeks of age, especially if they’re exposed to other dogs. It’s also known as kennel cough or infectious tracheobronchitis and is common in dogs in kennels or boarding situations.

The leptospirosis vaccine can be started at 12 weeks of age. At this time, puppies can also be dewormed and started on flea-and-tick prevention to prevent infestations. Depending on the age of your puppy and your state laws, puppies can receive a rabies vaccine starting at 12–16 weeks of age. This would be best discussed with your veterinarian.

Ideally, your puppy should be fully vaccinated before interacting with other dogs at around 16 weeks of age. However, socialization in puppies is also crucial. If there are puppy socialization classes near you, you may be able to sign up for one that has puppies of similar ages and vaccine status. If you would like to bring your puppy out in public, you can do so by holding and carrying them around, to lessen the chance of disease transmission from other dogs.

If you’re unsure about your puppy’s health, growth, or vaccine schedule, its recommended that you contact your vet.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's an online service where you can talk to a vet online and get the personalized advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

Dogster_Website dividers_v1_Jan 18 2024-03

Conclusion

Puppies have an underdeveloped immune system, which can make them more susceptible to certain diseases. Taking precautions like vaccinating and supervising interactions with other dogs and places is crucial. Avoid places where the unknown vaccination status of dogs is frequent, such as dog parks, until your puppy is fully vaccinated.

Sources

Featured Image Credit: Hryshchyshen Serhii, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

4 Awesome Australian Shepherd Haircuts (With Pictures)

Australian Shepherds shed moderately due to their double coats, so keeping up with a grooming routine is crucial to avoid mats and tangles....

Can Dogs Be Allergic to Peanut Butter? Our Vet Explains the Signs, Risks & FAQ

Most dogs love peanut butter, but can they be allergic to this treat that they love so much? Like humans, dogs can be...

Can Dogs Eat Vegetables? Vet-Verified Nutrition Facts, Safe Options & Benefits

Domestication has profoundly affected our canine companions. They have gone from carnivorous predators to pampered pets. Roughly 95% consider them members of their...

9 Best Salmon Dog Foods in 2025 – Reviews & Top Picks

Many dog owners are choosing to feed their dogs food that contains salmon as the main ingredient because of the benefits this fish...

More related

White Beagle Dog Breed: Info, Pictures, Care & More

Strictly speaking, an all-White Beagle doesn’t conform to breed standards, and what is often described as a White Beagle will have some color...

10 Best Dog Training Podcasts in 2025

Podcasts offer a little something for everyone. Whether you’re looking for true crime or a deep dive into a particular fandom, there’s a...

7 Ball Games for Dogs to Try With Your Pet

If you have a dog and a ball, that’s all you need for a great time! Whether your dog can’t get enough of...

13 Pet Industry Statistics in the Philippines to Know in 2025: Trends, Market Size & FAQ

Note: This article’s statistics come from third-party sources and do not represent the opinions of this website. With its population of around 18...

Keep reading

5 Best Sources of Iron for Dogs (& How Much They Need Daily)

Many lifeforms need iron to survive, from wild animals like giant blue whales and African lions to domesticated pets like dogs and cats. Iron has many important qualities, so it’s abundant in different sources of food. Most commercial dog food...

Siberian husky-dog-puppy-eating-a-meat_Hyper-Set_shutterstock

What Fruits Can Dogs Eat? 13 Vet-Approved Options

Summer is right around the corner, and if you’re anything like me, you’re probably excited about all the in-season fruits you’ll be able to eat soon. You might also be curious about which fruits, if any, are safe to offer...

Labrador retriever dog eats watermelon from hands

7 Best Taste of the Wild Dog Foods in 2025 – Reviews & Top Picks

Dogs have always been known for their hearty appetites, and this is especially true of those that are bred to be active. Today, there is an abundance of different types of dog foods on the market, each with its own...

Maltese dog eating from a bowl

Can Dogs Eat Mango? Vet-Approved Safety & Feeding Tips

No matter what you’re eating, your dog likely stares on with envy. Most dogs love to eat what their humans eat, but dogs have no idea if the food is good or bad for them or possibly even downright toxic—this...

Can Dogs Eat Mango

10 Best Dog Foods for Sensitive Stomachs in 2025 – Reviews & Top Picks

Finding the right dog food for your dog can take time, and it’s extra challenging when your dog has a sensitive stomach. Pet food companies are all regulated by the Food and Drug Administration (FDA) to ensure that they are...

fluffy dog eating dry kibble from elevated bowl

Can Dogs Eat Hot Sauce? Vet-Verified Health Facts

Some people like their food to be extra spicy, with hot sauces being a $1.65 billion market in the United States. Of course, not everyone likes the heat. That includes your dog. Wild or domestic canines don’t encounter this taste...

Can Dogs Eat Hot Sauce

Simply Nourish Dog Food Review 2025: Pros, Cons, Recalls & FAQ

Is Simply Nourish dog food a good choice for your pet? That’s what we’ll be exploring in this article. We’ll take a look at the pros and cons of this brand, as well as any recalls that have been issued...

Simply Nourish Dog Food - Featured Image

10 Best Dog Foods for Rhodesian Ridgebacks in 2025 – Reviews & Top Picks

The Rhodesian Ridgeback is a beloved family member in many households around the world. These medium-large-sized, sweet, and sensitive dogs are equally intelligent and energetic, making them the perfect friend, playmate, and jogging partner. They’re also a healthy breed for...

Rhodesian Ridgebacks