Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Great Dane Chihuahua Mix: Is It Possible? Vet-Verified Facts, Ethics & Risks

Share

Purebreed chihuahua puppy and a great dane sniffing each other

Mixing large dogs with small dogs is a controversial topic, especially if it’s done intentionally. So, while many people may be curious if it’s possible to breed a Great Dane and Chihuahua, the answer is it is possible; however, that doesn’t mean it’s an ethical or safe combination. Let’s learn more.

divider dog paws 4 oct 2024

Great Danes and Chihuahuas Can Technically Breed

Great Danes and Chihuahuas certainly have the capability to breed, but that doesn’t mean it’s safe. Because of the insane difference in size between a Great Dane and a Chihuahua, the sex of the Chihuahua and Great Dane parents matter.

A female Chihuahua wouldn’t be able to carry the size of puppies that a Great Dane cross could produce. It could be a risk to her health as well as the puppies. If your Chihuahua is accidentally bred by a giant breed, like a Great Dane, speak to your veterinarian about the safest option.

Did you know you can speak to a veterinarian without having to travel? Just head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

Now, if you’re looking at it the other way around, it should be possible for a Great Dane female to carry and whelp a litter of Chihuahua cross puppies. However, it may be very difficult for the male Chihuahua to get her bred in the first place due to the differences in size.

The best option is by artificial insemination of a Great Dane female.

Great Danes and Chihuahuas Shouldn’t Mix

Just because a Great Dane and Chihuahua could create life doesn’t mean it’s ethical to do so, especially intentionally. Many designer dog crosses have become very popular due to their uniqueness, but creating a cross that puts one of the parent dogs at risk shouldn’t be done.

Avoid breeders that say they have produced a Great Dane/Chihuahua cross, even if the breeding was done through artificial insemination. This may be just another gimmick to sell dogs rather than a responsible way of producing animals.

Also, when getting a crossbreed dog, you really don’t know what you’re going to get. The size and temperament can be a range between what the two parent breeds are typically like. So, when you’re dealing with dogs as different as a Great Dane and Chihuahua, it can very much be a wildcard.

Great Dane and chihuahua dog looking to each other
Image Credit: Natallia Yaumenenka, Shutterstock

divider dog paws 4 oct 2024

What to Expect from a Great Dane Chihuahua Mix

If you have a dog that definitely has some Chihuahua and Great Dane in their DNA, what could they possibly be like? There are tons of possibilities, so there is no one-size-fits-all answer..

Size

As far as size goes with this combination, the Great Dane Chihuahua Mix can range anywhere from slightly bigger than a Chihuahua to slightly smaller than a Dane. However, most generally, they would fall somewhere in the middle.

Personality

Chihuahuas are fiery, feisty, and free. They are often very selective of who they get close to and they can be aloof or even aggressive with others. These little dogs can be both loving to those they know and nippy to those they don’t.

Great Danes are typically fun-loving, goofy dogs with protective undertones. They tend to be very close to every member of the household but might be a little suspicious or standoffish with strangers.

When you combine the two, aggression could definitely be at the forefront of concerns. It’s highly crucial to properly socialize your dog as they will need exposure to all sorts of new situations to desensitize them and make everything go smoothly.

DNA Testing for Dogs

If you think your crossbreed dog has a little of both Great Dane and Chihuahua in them, there is one way to know for sure. DNA testing is quite possible on dogs. Knowing what breeds make up a dog can help you to understand potential health conditions or behavioral problems that could develop so that you can get a jump on them.

There are different means of testing you can do, some of what you could do from the comfort of your own home. You can also contact your vet to see if they offer any type of DNA service.

divider dog paws 4 oct 2024

Conclusion

Since both Great Danes and Chihuahuas are canines, they are capable of producing offspring, but that doesn’t mean it’s a good idea. Due to their vast size difference, breeding these different dogs can create some real health issues for the parents and is likely best done through artificial insemination. The outcome of the breeding can be vastly different as well, with a decreased ability to estimate size and temperament of the Great Dane Chihuahua Mix puppy.


Featured Image Credit: pixshots, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.




How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Dogster’s Weekly Photo Contest Winners: Best Easter Photo (April 9, 2026)

Every week our team gets the privilege of sorting through our readers photos to choose what dogs will win this weeks contest! See...

We Didn’t Just Add a Dog to Our Life – We Built a Life With Him

“We didn’t just bring a dog home—we built a life together.” Most people are quietly taught a version of pet ownership that looks...

What Most Airlines Won’t Let You Do With Your Dog (Even If You Pay Extra)

Airline pet policies are notoriously hard to navigate. The information is scattered across different pages, buried in FAQ sections, and often contradicts what...

Designer Breeds: Best of Both? New Study Says No

“I’ll take a highly trainable, low-shedding lapdog, hold the heart disease and anxiety!” Something I always found amusing was when people would point...

More related

Do Hypoallergenic Dogs Exist? What Science Says

Hypoallergenicity has become an essential focus in the pet world in recent decades as breeders look for new ways to cater to allergy-suffering...

Male vs Female Rhodesian Ridgeback: What’s The Difference (With Pictures)

The Rhodesian Ridgeback dog breed is a loyal and assertive dog that is always willing to please its owners. This medium to large...

What to Feed a Nursing Dog to Increase Milk Production: Vet-Explained Nutrition

When a mother dog is producing milk, she needs to feed herself to feed her puppies. She needs water, calories, protein, fats, vitamins,...

Are My Dogs Attracted to Danger? Yes.

Hi, I’m Allison! Read my introduction to learn more about me and my three mixed-breed dogs from Thailand, Jelly, Lorraina, and Manic. Many...

Keep reading

Can Dogs Eat Jalapeños? Vet-Reviewed Health Facts

We humans have a much more varied diet than any of our four-legged companions. Our pantries and refrigerators are full of foods that our doggies would just love the opportunity to get their paws on, but we have to be...

Can Dogs Eat Jalapeños

Can Dogs Eat Corn Flakes? Vet-Approved Advice & Precautions

You wake up in the morning and enjoy a bowl of corn flakes for breakfast. While enjoying your breakfast, you notice your dog looking at you intently, begging to have a bite of whatever delicious food you’re eating. As a...

Can Dogs Eat_Corn Flakes

10 Best Canned Dog Foods for Picky Eaters in 2026: Reviews & Top Picks

While it can be a mystery as to why some dogs are picky, finding dog food that a picky dog enjoys can feel like an even greater mystery to solve. Many dog owners have found solutions with meal toppers and...

shih tzu dog getting wet food from owner at kitchen

10 Best Raw Dog Food Delivery Services in 2026 – Reviews & Top Picks

It can be overwhelming to choose food for your dog, especially a raw diet. Raw diets have been becoming popular, so many companies are offering raw foods. However, that doesn’t mean all companies produce balanced, high-quality raw diets. We’ve compiled...

raw dog food

Can Dogs Eat Rye Bread? Vet-Verified Nutrition Facts & FAQ

Sharing food comes naturally to us. It doesn’t matter if it’s our family or a friend; it’s a bonding experience. Therefore, it’s not a stretch if the things we want to give our dog extends to many tasty morsels we...

Can Dogs Eat Rye Bread

Can Dogs Eat Fried Chicken? Vet-Verified Risks, Alternatives & FAQ

The hot pop of frying chicken sends dogs flying from the sofa just as easily as a tantalizing takeout box from your favorite chicken chain. It may be finger-licking good, but is it safe and healthy for your dog? Unfortunately,...

Can Dogs Eat Fried Chicken

Can Dogs Eat Raw Chicken? Vet-Verified Dietary Facts & FAQ

Chicken is a common and healthy ingredient in many dog foods, and plenty of pet parents love to feed their dogs plain-cooked chicken. If you’ve been considering feeding plain chicken to your dog, you may have wondered whether you can...

Can Dogs Eat Raw Chicken

Can Dogs Eat Pears? Vet-Approved Facts & FAQ

It’s natural to wonder what foods are safe for your dog to consume, as it’s common to want to toss them a quick piece of meat or veggies while you’re at the dinner table. But what about fruit? More specifically,...

Can Dogs Eat Pears

Love Dogs? So Do We! Join the Dogster Community

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.




Sign up for the Dogster Email Newsletter