Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Can You Buy Heartworm Medicine Over the Counter for Dogs? Vet-Reviewed Facts & FAQ

person feeding poodle pet dog with preventive heart worms chewable

As important as it is for regulatory institutions to control prescriptions, many owners find it odd that heartworm medicine isn’t available over the counter. After all, heartworm preventives aren’t like medications provided on a case-by-case basis. Since every dog needs them, why wouldn’t they be as easy to obtain as possible?

It may seem needlessly complicated, but regulatory institutions and services have several reasons for making these preventives a prescription. Let’s discuss how we obtain heartworm medicine and why sticking to the process is the surest and safest way to protect our dogs.

divider dog paws 3 oct 2024

Can You Buy Heartworm Medicine Over the Counter For Dogs?

Heartworm medicine is available by prescription only. Sites like Chewy or PetMeds offer 30-day topical products or chewable tablets, but they still require a prescription to place an order. Alternatively, vets can provide an injection that lasts six or 12 months.

dog getting injected at the veterinary clinic
Image Credit: Ground Picture, Shutterstock

What Are Heartworms in Dogs?

Heartworm prevention is a serious matter for vets, particularly regarding dogs. Canines are the definitive host for heartworms. Heartworms are passed when a mosquito ingests microfilaria from an infected dog. Once inside the mosquito, the microfilariae become infective larvae and can be transferred to another dog with the mosquito bites them. The larvae can take up to 6 months to mature into adults, so dogs won’t typically show physical issues for quite a while.

Most dogs will only experience mild signs in the early stages of heartworm disease. The first sign to show up is often a persistent cough. The longer the infection goes without treatment, the worse the signs can get.

Chronic and severe infections can lead to clinical signs including:
  • Exercise intolerance
  • Rapid or labored breathing
  • Decreased appetite and weight loss
  • Fainting

In worst-case scenarios, heartworms can cause heart failure and caval syndrome which is when large numbers of worms block the blood supply to parts of the heart. The prognosis for dogs with caval syndrome is very poor, and these dogs often die even with surgery.

divider dog paws 3 oct 2024

Why Is Heartworm Medicine Prescription Only?

The effects of heartworm infections can be dire, and the treatment is arduous and stressful. An infected dog needs several weeks of medicine to kill the adult and larval heartworms, all while staying relaxed and relatively sedentary. Vigorous activity can result in blood clots, stroke, or even death.

Due to the risks inherent in dogs having heartworms and the treatments to remove them, we can’t overstate the importance of proper prevention. Heartworm medicine is prescription-only to ensure it’s effective, safe, and properly administered at the correct dosage, as well as due to the potential serious side effects related to treating a dog with a high worm burden.

labrador retriever dog lying on the floor looking sad or sick
Image Credit: Jaromir Chalabala, Shutterstock

Specific Dosing

Dogs come in all sizes and body types. As with most medications, providing the correct heartworm medicine depends on the dog’s weight and specific tolerances. Giving the wrong product or amount can expose dogs to adverse reactions or may be ineffective.

For example, some Collies and similar dog breeds may have an MDR1 gene mutation that makes them uniquely sensitive to the medication ivermectin, as well as some other medicines. Although toxicity is unlikely at the low doses in 30-day tablets, products containing ivermectin should be used with caution and under veterinary guidance in dogs with this mutation because, at high doses, they’re more likely to cause issues like lethargy, ataxia, tremors, and other neurological signs.

Since heartworm medicines aren’t OTC, vets control the process to provide suitable medicine in the proper dosage, tailored to each dog and their circumstances.

Well-Timed Administration

Letting time lapse between 30-day, bi-annual, or annual heartworm medications creates a window of opportunity for parasites to infect your pet. Many 30-day treatments have a minor buffer past their 30-day range, but it’s easy for owners to skip the doses entirely.

By making heartworm medicines available only through your dog’s doctor, timing the administration can involve a reminder from your vet. Owners will be much less likely to miss a dose when they have that support, ensuring their dogs are always protected.

divider dog paws 3 oct 2024

The Importance of Heartworm Testing

Heartworm prevention coincides with heartworm testing, which is an annual requirement. Veterinarians perform blood tests to look for heartworm antigens or microfilariae in the dog’s system. Once they confirm a dog is parasite-free, they can prescribe another 12 months of treatment.

Testing may seem redundant if you’ve given your dog heartworm medicine responsibly. If there have been no lapses between doses, why would you need to check for worms before prescribing more? Vets insist on it to verify the medicine’s effectiveness and account for medication-resistant heartworms, as heartworm presence is increasing, while the number of dogs receiving preventative care is unfortunately reducing.

blood samples of a dog for lab testing
Image Credit: hedgehog94, Shutterstock

Medication-Resistant Heartworms

Heartworms resistant to macrocyclic lactones (MLs), the active ingredients in heartworm preventives, are an isolated but growing issue. Since 2005, experts have recognized the loss of efficacy of every ML against certain strains, prompting the FDA to look for new solutions.

Resistant parasites are a particular concern in Southeast regions like the Mississippi Delta.

Even if dogs receive timely treatments, a slight chance of infection remains that only blood tests will reveal. Without screening, dogs could harbor resistant strains for years. Alongside the harm to their body, this could allow the resistant parasites to attack other dogs in the area. Annual exams let practitioners track, study, and react to heartworm cases, helping to prevent their spread.

Preventing Adverse Effects

Without testing, you could give your dog prevention medicine while they secretly have heartworm. Not only would this be a waste of time and money and risk the spread of heartworms, but it could also cause serious adverse reactions that can be harmful to your dog’s health, as the preventative products do not kill the adult heartworms.

When an infected dog takes a standard heartworm preventive, the medicine may cause young heartworm larvae to die rapidly which can trigger a shock-like reaction. Although this is rare, a heartworm test is a simple way to prevent a potentially fatal situation.

divider dog paws 3 oct 2024

Which Home Remedies Can I Give for Heartworms?

Although numerous brands sell herbal heartworm medicines that don’t need a prescription, no studies have evaluated their effectiveness. Many manufacturers acknowledge the products shouldn’t replace preventatives. Natural remedies may help boost immunity and manage the side effects of treatments, but they aren’t proven to prevent or treat heartworms in dogs.

However, natural remedies can protect dogs when used as mosquito repellents. Though they don’t remove the need for heartworm preventatives, natural mosquito repellents offer another way to reduce the risk of transmission.

Products like Vet’s Best mosquito repellent and natural herbs may help your dog stay bite-free. Since many essential oils, herbs, and human products (like DEET) can be toxic to dogs, discuss safe at-home solutions with your vet before using them on your dog.

Did you know you can talk to a vet online? Click on the image or button below to schedule a call: PangoVet_Mention-in-Content Savings V1


Is There Any Way to Get Heartworm Medicine for Dogs Over the Counter?

A common way some owners try to sidestep getting a heartworm prescription is to use ivermectin intended for larger animals. Ivermectin for horses is available OTC at feed stores. Many people think scaling down the dose can prevent heartworms at a fraction of the cost of medicine for dogs.

However, heartworm preventives for livestock are exceptionally potent and highly dangerous to dogs. Dogs can suffer ivermectin poisoning simply by getting into manure from animals that have been treated with ivermectin. When administering a paste, scaling down to a safe yet effective amount is extremely challenging.

It’s easy to give too much and cause a veterinary emergency, and it’s almost impossible to tell whether you administered enough to make it effective. The only person who can advise on using these non-canine medicines is your vet.

It doesn’t make sense for people who can get safe and effective heartworm medicine for dogs just as easily. Play it safe, and stick to testing and prescriptions through your vet.

Anti mosquitoe and anti-insect for active dog outdoors
Image Credit: Aleksey Boyko, Shutterstock

divider dog paws 3 oct 2024

Final Thoughts

With the risks surrounding heartworm disease and its treatment, owners owe it to their dogs to take the issue seriously. It only takes one missed test or the wrong dose to set a pet up for potentially lifelong complications. Though avenues exist for owners to try to sidestep prescriptions and get OTC heartworm medicines, working with a vet is the only responsible route to prevent a potentially fatal infection.


Featured Image Credit: ThamKC, Shutterstock

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

10 Awesome DIY Christmas Gifts for Dogs & Dog Lovers (With Pictures)

Christmas is a time of joy, peace, and love. It’s also a time to get people presents that you’ve wanted to get them...

Can Dogs Eat Palm Oil? Vet-Verified Facts & Info

You probably don’t have a bottle of it in your pantry. However, you probably consume palm oil every day. It’s big business, with...

20 Brown Dog Breeds: Big, Small & Fluffy (With Info & Pictures)

You might be surprised to learn there are more than 150 recognized dog breeds in the United States, and there are another 75...

8 House Rules for Dogs & How to Set Them: A Vet-Approved Guide

Getting a dog isn’t all sunshine, frisbees, and couch cuddles; it’s also a lot of hard work in planning how the dog is...

More related

10 Best Puppy Foods in Canada in 2025 – Reviews & Top Picks

Congratulations on welcoming home a new puppy. This exciting and fun time in both of your lives may come with a lot of...

Worms in Dog Poop: Our Vet Explains Signs, Causes & Treatment

Seeing little white worms in your dog’s poop can be alarming, but it’s important to know that intestinal worms are common in canines....

8 Best Low Sodium Dog Foods In 2025 – Reviews & Top Picks

There are tons of dog foods out there—so much so that some pet stores have almost half of their floor space dedicated to...

10 Awesome DIY Dog Christmas Decorations & Ornaments (With Pictures)

The holiday season is here faster than you might think — before you know it, it’s time to start decorating the house! If...

Keep reading

Can Dogs Eat Banana Peppers? Vet-Reviewed Nutrition Facts & FAQ

Next time grilling season rolls around, you may find yourself throwing some peppers on the grill, but when your dog comes over to give you those puppy dog eyes, you might wonder if they can eat peppers. In some cases,...

Can Dogs Eat Banana Peppers

Aldi Pure Being Dog Food Review 2025: Recalls, Pros & Cons

Review Summary Aldi Pure Being is made with meat as the main ingredient in their foods. The dog food is an excellent option for pet owners on a budget. You can rest assured that the food is balanced and nutritious...

Dogster_Aldi Pure Being Dog Food Review

Is Sportmix Dog Food Made in the USA? What You Need to Know

Sportmix dog and cat food are manufactured by Midwestern Pet Foods, a subsidiary of Nunn Milling Company, Inc. This is a fourth-generation, family-owned business that started in 1926 in Evansville, Indiana. All Sportmix pet food formulas are made exclusively in...

pouring dog food in food bowl

How Much Does Dog Food Cost in 2025? Average Prices & Buying Tips

Pet food has experienced an inflation rate of about 1.97% per year since 1997. Back then, you could buy the same amount of dog food for $20 that you would need to spend more than $30 on today. Therefore, we...

pouring dog food

Can Dogs Eat Pesto? Vet Approved Facts & Safety

Pesto is one of those delicious sauces that can completely transform the taste of any old dish into something magical and sumptuous. If you like using pesto when baking bread or serving pasta, you’re probably wondering if it is okay...

Can Dogs Eat_pesto

How to Start a Dog Food Business: 10 Tips & Tricks

Given how important nutrition is to pet health, starting your own dog food business can be an interesting and even lucrative idea. Indeed, according to IBISWorld, the pet food industry brings in $27 billion a year, and it is growing...

Pet Food Packets At Store

Diamond Naturals Dog Food Review 2025: Pros, Cons, Recalls & FAQ

Review Summary Diamond Naturals is one of the many pet food lines produced by Diamond Pet Company, a second-generation, family-owned manufacturer. Made entirely in the USA, Diamond Naturals is also sold in 100 countries around the world. With a commitment...

Dogster_Diamond Naturals Dog Food Review

Meridian Dog Food Review 2025: Pros, Cons, Recalls, and FAQ

Review Summary Meridian is a holistic pet food company that is made by Midwestern Pet Foods under the parent company Nunn Milling Co. Meridian makes four different dog food recipes with an aim at high quality, natural nutrition. We all...

Dogster_Meridian Dog Food Review