Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Heterochromia in Dogs: Different Colored Eyes Explained

Share

heterochromia dog

Have you ever noticed a dog with two different colored eyes, or maybe they had two colors in the same eye? What you saw was a condition called heterochromia. Heterochromia can produce beautiful and interesting eye appearances in dogs, but what is it, what causes it, and should you be concerned if your dog has it?

divider dog faces oct 2024

What Is Heterochromia in Dogs?

Heterochromia is a condition in which the eyes are different colors from each other. This means that the irises, the colored part of the eyes, are not the same in both eyes. In most cases, the eyes otherwise appear completely normal.

There are a few types of heterochromia, which we’ll talk about in a minute. This condition can be hereditary, which means that your dog was born with the condition and it began to become visible as they got their permanent eye color around 7 weeks of age. It can also be acquired, which means that some external cause led to a change in the eye colors.

siberian-husky-with-heterochromia-odd-eyes
Image Credit: travelarium.ph, Shutterstock

What Causes Heterochromia in Dogs?

Hereditary heterochromia is closely related to coat color and pattern, with dogs that are dapple, merle, white, or notably white around the head and eyes having a greater likelihood of having the condition. The color of a dog’s irises is determined by how much melanin is present in the eyes. Dogs with brown eyes have a large amount of melanin, while dogs with blue eyes have none in the stroma, the thickest part of the iris and the one that determines eye color. Dogs with heterochromia can have different amounts of melanin in each eye, or they may even have greater and lesser concentrations of melanin in different parts of the iris of the same eye.

Acquired heterochromia is less common than hereditary heterochromia, and it involves some eye conditions. It is caused by external factors that permanently impact the color of the iris in affected dogs. Inflammatory conditions, immune-mediated problems, certain medications, and injuries to the eyes and head can cause acquired heterochromia. In some cases, eye conditions that alter the clarity of the cornea or the eye may be mistaken for heterochromia, like glaucoma or cataracts.

divider single dog paw oct 2024

Types of Heterochromia in Dogs

1. Complete Heterochromia

In complete heterochromia, both eyes are completely different colors from each other. The dog is likely to have one dark eye and one light eye. Most dogs with complete heterochromia have one brown and one blue eye.

border-collie-with-heterochromia_Tattiliana_Shutterstock.jpgDecember 3, 2
Image Credit: Tattiliana, Shutterstock

2. Sectoral Heterochromia

Sectoral heterochromia means that only a section of the dog’s iris is blue, while the rest of the iris is a different color. This can occur in one or both eyes at the same time.


3. Central Heterochromia

Central heterochromia creates a haloed appearance of the iris. In this condition, the iris will have multiple colors within it, with one color radiating from the pupil mixing with the other eye color in a spiky pattern. Like sectoral heterochromia, central heterochromia can impact one or both eyes.

divider single dog paw oct 2024

Are There Health Concerns With Heterochromia in Dogs?

Hereditary heterochromia, the one present in your dog since birth, in and of itself is not dangerous, nor is it associated with causing any health conditions. The only exception to this is that Dalmatians with partial or sectoral heterochromia may have a higher risk of also being deaf.

That said, if you notice any sudden color changes occurring in your dog’s eyes, they should see a veterinarian as soon as possible.

Sudden color changes within the eyes can indicate
  • injury
  • uveitis
  • glaucoma
  • clotting problems
  • cataracts
  • retina problems
  • optic nerve problems
  • corneal degeneration problems

Keep in mind that puppies will have light bluish eyes when they are born, and as they grow, around 7 weeks of age, they will develop their adult eye color, so keep this in mind if you notice color changes within the eyes of a growing pup. However, consult with your vet immediately if in doubt or if they seem to be showing signs of discomfort, eye problems, blindness, deafness, or other conditions.

red-Catahoula-Leopard-Dog-mixed-breed-dog-with-sectoral-heterochromia-in-its-eyes
Image Credit: Marry Swift, Shutterstock

What Breeds Are Most Likely to Have Heterochromia?

Heterochromia can occur in any dog breed; however, it can be seen more often in certain breeds in which ocular color dilution is found.

In Dalmatians, heterochromia seems to occur more frequently in female dogs, but this is not necessarily true in other breeds.

Sudden or gradual changes in eye color and appearance should always be assessed by a veterinarian.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

divider dog paws 3 oct 2024

Frequently Asked Questions

Can Heterochromia Occur in Other Animals?

Yes, heterochromia can occur in cats, as well as humans. It can also occur in horses, cattle, and many other animals. Although more common in animals than in humans, heterochromia is still considered uncommon to rare among all animals it occurs in.

Can Heterochromia in Dogs Be Treated?

Since hereditary heterochromia isn’t considered a problem on its own, there is no need to treat it. If your dog has acquired heterochromia, though, then it’s important to work with your veterinarian to identify the cause. Problems with the eyes are typically considered to be emergencies because some conditions can rapidly result in the loss of vision.

Heterochromia-and-Segmental-Heterochromia in a husky dog
Image credit: Enmanuel Q, Shutterstock

Is Heterochromia Caused by Inbreeding?

Heterochromia can be the result of inbreeding, but the presence of heterochromia doesn’t indicate that inbreeding has occurred. In domestic animals that experience heterochromia, inbreeding may play a role due to the inbreeding that often occurs to develop breeds. However, this inbreeding may have occurred many generations ago. Heterochromia can be caused by a recessive gene, though, which means that two unrelated carriers of the gene may still have offspring with the condition.

Are There Any Cultural Beliefs Surrounding Heterochromia?

Yes, many cultures currently have or previously had beliefs related to heterochromia. Some Native American cultures carry the belief that dogs with heterochromia can see both the earth and the heavens at the same time. In some cases, this belief extends to humans and other animals with heterochromia as well. In some ancient European cultures, heterochromia was associated with witchcraft.

divider dog faces oct 2024

Conclusion

Heterochromia is a fascinating condition that can result in some extremely beautiful and unique eyes. This condition is considered to be harmless on its own, but it can be indicative of a more serious issue. If you have a dog with heterochromia, you should be proud of the uniqueness of your pup!


Featured Image Credit: Jairo Alzate, Unsplash

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.




How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Dogster’s Weekly Photo Contest Winners: I’m a Messy Eater (March 26, 2026)

Every week our team gets the privilege of sorting through our readers photos to choose what dogs will win this weeks contest! See...

The Itchy Dog Survival Guide: Home Remedies That Help

Allergies in dogs are more common than most people realize, and they’re genuinely hard to pin down. The immune system overreacts to something...

Another Winner, Another Controversy

Still recovering from the disappointment of seeing a docked & cropped dog awarded Westminster Kennel Club’s “Best in Show,” only to be kicked...

Dogster’s Weekly Photo Contest Winners: My Favorite Toy (March 19, 2026)

Every week our team gets the privilege of sorting through our readers photos to choose what dogs will win this weeks contest! See...

More related

Do Golden Retrievers Drool Excessively? 7 Vet-Verified Causes Explained

It is normal for dogs with drooping jowls, such as Bloodhounds, Saint Bernards, and Mastiffs, to drool a lot. But, excessive drooling, medically...

Can Dachshunds Run Fast? Average Speed & Breed Comparison

Dachshunds are short-legged, long-body dogs that love digging in the mud. Due to their tiny stature, many people naturally think these dogs won’t...

Whole Earth Farms Dog Food Review 2026: Recalls, Pros & Cons

Review Summary If you’re a pet parent, then you’ve probably already heard of Whole Earth Farms dog food just because of their tagline,...

Do Dogs Have Toe Beans? Vet-Verified Paw Anatomy Explained

The term “toe beans” is used to describe the padded parts of a dog’s paws that can resemble jellybeans. Although dogs do technically...

Keep reading

HEB Heritage Ranch Dog Food Review 2026: Pros, Cons & FAQ

Review Summary HEB is an American supermarket that is centered in Texas. They have a few locations in Mexico, as well, but for the most part, their stores are found within Texas. Heritage Ranch is their brand of dog food....

Dogster_HEB Heritage Ranch Dog Food Review

Can Dogs Eat Bell Peppers? Vet-Verified Nutrition Facts & FAQ

If you have a dog, you know they love meat, which isn’t surprising since they were once predators that hunted other animals to survive. What is surprising is how many other foods the average dog loves, from bananas and cheese...

Can Dogs Eat Bell Peppers

Maev Dog Food Review 2026: Recalls, Pros & Cons

Review Summary Have you heard of the newest pet food craze of raw dog food? Does it sound like something you want to serve your dog? Maev is a relatively new dog food brand, launched in 2020 and made in...

Dogster_Maev Dog Food Review

8 Dog Birthday Cookie Recipes to Treat Your Pup With

This article has been reviewed by a veterinarian for safety. The recipes included in this article will be suitable for most dogs however, it does not take your dog’s circumstances and health status into account. It is your responsibility to...

Dog Birthday Cookie Recipes to Treat Your Pup With

5 Vet-Approved Carob Dog Treat Recipes to Make at Home

You know chocolate is toxic to canines, so giving it to your pup is out of the question. But sometimes those begging eyes are so hard to resist! However, while you can’t feed your dog real chocolate, you can feed...

Carob chocolates for dogs

Can Dogs Eat Bugs? What the Science Says

Any dog owner has probably seen their dog eat a bug here and there, as dogs love to snoop and sniff outdoors. Dogs are curious beings and love to investigate the world around them, which can mean playing with a...

Can Dogs Eat_bugs

10 Best Affordable Dog Foods for Labs in 2026 – Reviews & Top Picks

Anyone who’s ever owned a Labrador Retriever knows that they love their food…a lot. In fact, a study has shown that a gene mutation associated with weight and food motivation has been found in Labradors. This means that Labs are...

labrador retriever eating dog food

10 Best Low-Calorie Dog Foods in 2026 – Reviews & Top Picks

If your dog recently stepped on the scale and the number was a bit high, you know it’s time to make some changes. It’s not uncommon to see a chubby animal hobbling around a park or sidewalk these days. In...

Samoyed eating

Love Dogs? So Do We! Join the Dogster Community

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.




Sign up for the Dogster Email Newsletter