Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Can Dogs Have Aspirin? Our Vet Discusses Safety Facts

White aspirin pills on blue table

Since people can pick up over-the-counter pain relief medication for themselves, you might be tempted to think the same is true for our pets. The truth is that human over-the-counter pain relief options are not ideal for our pets. Most of these medications fall under the class of drugs known as NSAIDs or “non-steroidal anti-inflammatories,” and the US Food and Drug Administration (FDA) has not approved any over-the-counter NSAIDs for use in dogs.1 That being said, veterinarians may prescribe aspirin off-label at the correct doses if your dog is a good candidate for the medication.

divider dog paws 3 oct 2024

Can Dogs Have Aspirin?

Aspirin is an NSAID medication and blood thinner. The NSAID part of the medication refers to aspirin’s role in reducing fever, pain, and inflammation through the inhibition of compounds called prostaglandins. It also inhibits thromboxane, which is involved in blood clotting, hence the blood thinning effects.

In veterinary medicine, aspirin has largely been replaced by other NSAIDs and anticoagulants. There is a “safe” dose of aspirin for some dogs. However, dogs may be more sensitive to the adverse effects of aspirin than people are, and there are plenty of reasons why aspirin should not be used in certain dogs.

Owner giving medicine in a pill to his dog
Image Credit: Creative Cat Studio, Shutterstock

Is Aspirin Harmful to Dogs?

Depending on the amount of aspirin given, the weight of the dog, and any underlying health conditions, aspirin can have some adverse effects—the most common of these being gastrointestinal upset.

Stomach ulcers and intestinal bleeding can occur because certain gut-protecting prostaglandins are suppressed by aspirin. Another role of prostaglandins in the body is to maintain kidney blood flow, so side effects related to the kidneys are not uncommon.

The use of NSAIDs tends to be avoided in patients with pre-existing kidney problems. Once in the body, it’s mostly cleared by the liver, so dogs with certain liver diseases need to have lower doses to avoid accidental overdose. Since aspirin is an anticoagulant, its use in dogs with clotting disorders or on other similar medication is inadvisable.

Aspirin should never be used in combination with other NSAIDs or prednisolone. It should be used cautiously with diuretics, like furosemide, and other heart medications. Other drugs and even supplements like glucosamine and omega fatty acids can interfere with aspirin use. Since there are so many drug interactions, knowledgeable use is needed to avoid adverse events in your dogs.

If your pet has been prescribed aspirin, you will need to monitor for the following signs and reach out to a vet if they occur:

  • Vomiting
  • Reduced appetite
  • Lethargy
  • “Coffee ground” vomit (caused by gastric bleeding)
  • Black tarry stools (caused by gastric bleeding)
  • Diarrhea
  • Abnormal bleeding or bruising
  • Increase thirst
  • Increased or absent urination
jack russell terrier dog vomiting outdoor
Image Credit: Enrico Spetrino, Shutterstock

If aspirin is accidentally overdosed (like your dog got into a pack of aspirin, for example), they can be at serious risk of severe side effects, even death. And if they already have a clotting disorder, kidney disease, or liver disease, they are at even higher risk. Signs of a serious overdose include:

  • Pale gums
  • Increased respiratory rate
  • Hyperthermia
  • Wobbly gait
  • Tremors
  • Seizures
  • Coma
  • Bleeding
  • Death

divider dog paws 3 oct 2024

My Dog Got Into My Aspirin, What Do I Do?

If your dog has gotten into some of your aspirin by accident, immediately contact a veterinarian or the Pet Poison Helpline (855) 764-7661 or ASPCA Animal Poison Control (888) 426-4435.

Be prepared when you call to answer a few questions about your situation, like:
  • What medication has your pet ingested?
  • How many tablets have they ingested?
  • What dose (usually in milligrams or mgs) was in each tablet?
  • What brand/form of tablet was it? For example, were they enteric-coated tablets?
  • What time (or timeframe) did they ingest the tablets?
  • Is your dog showing any signs of illness, such as vomiting, diarrhea, inappetence, or lethargy?

If your pet has been overdosed, the information will let the experts make the best decision based on your situation. Sometimes, decontamination procedures like making your pet vomit and giving toxin binders are possible. In other cases, supportive care in a veterinary hospital might be needed to mitigate the adverse effects of the medication.

Extreme cases can be fatal or result in ongoing liver and kidney damage. Uncontrolled bleeding is another risk. If the gastric ulceration is severe, the stomach lining can be perforated, which allows gastric contents to leak into the abdomen. This is a life-threatening circumstance that causes septic peritonitis.

If you need urgent veterinary advice, consult a vet online.

Did you know you can speak to a veterinarian without having to travel? Just head over to PangoVet. It's an online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

Why Can’t I Give My Dog Over-the-Counter Medication?

There are a few reasons why you should never give your dog over-the-counter pain relief without the specific direction of a veterinarian. Firstly, these medications are designed with humans in mind and provide a dose for people. Because of their different biology, the human and dog dose rates for medication are different on a per pound of body weight basis. Even if the drug is safe for dogs, dogs are usually much smaller than people, and the human doses are often much too big for an average dog. Not only that but what is safe for one dog may not be safe for another since the size difference between dog breeds can be extreme.

Some over-the-counter medications are very toxic to animals. For example, cats cannot tolerate any dose of acetaminophen, and ibuprofen has a very narrow safe window in dogs (and is almost never used by veterinarians). Certain products have other ingredients, like caffeine, which are harmful to dogs. In addition, certain health conditions may mean that your pet should never take a specific medication. And if your pet is on other types of medications, it may be a contraindication too.

All medication has side effects that a veterinarian is aware of. They know the ins and outs of prescribing medication to animals of different species and with different health conditions. There is so much to know that you will very likely give the wrong amount, give a medication that is toxic to dogs, or give a medication that is contraindicated for your specific pet. If you do, the vet bills to treat the toxicity will likely be higher than what they were to treat your pet in the first place.

dog in vet clinic
Image Credit: Pickadook, Shutterstock

What Should I Do if My Dog Is in Pain?

If your dog is in pain, they need to be seen by a veterinarian who can diagnose what is going on and prescribe safe and effective pain relief for your dog. Veterinary visits are part of responsible pet ownership. Pet insurance can sometimes help you cover some of the financial costs associated with veterinary visits. If the veterinarian is not open, there is likely an after-hours clinic in the area where your dog can be treated. If not, the veterinarian should have some other after-hours options.

If you have a close veterinarian-client relationship with your local veterinarian and have been seen there recently, they may have your pet’s recent weight and bloodwork on file. This can help them make decisions about what should be done for your dog. If you are receiving pain relief for a chronic condition, you can talk to a veterinary team on the phone about next steps.

divider dog paws 3 oct 2024

Conclusion

While aspirin is occasionally used for pain relief by veterinarians, it has some risks, side effects, and a host of contraindications. Never give human medications to your dog unless it has been specifically prescribed by a vet. Keep your human pain relief medication away from your dog to avoid them accidentally being poisoned, but if they have gotten into some, call Animal Poison Control, Pet Poison Helpline, or a veterinarian.

Also see:


Featured Image Credit: Irin Fierce, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Can Dogs Eat Beef Liver? Vet-Approved Facts & FAQ

One of our biggest goals in life is to provide our families with what they need to be happy and healthy. This includes...

How to Potty Train a Dachshund (11 Vet-Approved Tips)

The typical Dachshund is a brave, cheerful, and friendly little dog. Dachshunds are always happy to see you and have a great time...

My Dog Has Too Much Energy, What Should I Do? 6 Vet-Reviewed Tips

Highly active dogs can be affectionate and playful, but pet parents sometimes find dealing with their energy demands challenging. Unfulfilled, these needs can...

Entlebucher Mountain Dog Breed: Info, Pictures, Origin & Traits

The Entlebucher Mountain Dog is a herding dog from Switzerland. They are the smallest of the four types of Swiss mountain dogs and...

More related

What Breed of Dog Is Zuma From Paw Patrol? Cartoon Dogs Presented

If you have a small child, you likely know about Paw Patrol. This show focuses on a little boy named Ryder and his...

Why Does My Dog Want to Go Outside Every 5 Minutes? 4 Vet-Verified Reasons

Dogs can be goofballs and provide us with daily entertainment. Most dogs love to have something to do to avoid boredom, such as...

10 Best Dog Breeds for Kids & Families: With Info & Pictures

What’s the best family dog breed? There are a lot of breeds that come to mind when you consider what makes a good...

How to Firm Up Dog Poop: 9 Vet-Approved Tips

Just like people, dogs can experience stomach upset that leads to loose stools and diarrhea. Some dogs simply have a sensitive digestive system...

Keep reading

10 Best Puppy Foods for Chihuahuas in 2025 – Reviews & Top Picks

One of the best-known toy breeds, the Chihuahua is a small, energetic dog bursting with personality. Most Chihuahua owners take their dogs everywhere, and they’re ideal “purse” dogs. Chihuahuas have unique energy needs, however. They require a balanced diet for...

two chihuahua puppies eating food from a bowl

Can Dogs Eat Bagels? Vet-Verified Nutrition Facts & Health Risks

Almost every dog owner has a hilarious story about their dog stealing their food. If your dog has stolen your bagel, it may seem funny (if slightly exasperating), but the truth is that bagels can be detrimental to your dog’s...

Can Dogs Eat_bagels

Can Dogs Eat Onions? Vet-Verified Toxicity & Safety Tips

Dogs are often indiscriminate about what they eat, so we have to be careful with what types of snacks and table scraps we feed them, as they may contain ingredients that are harmful to dogs. One common food to avoid...

Can Dogs Eat Onions

Can Dogs Eat BBQ Sauce? Vet-Verified Facts & FAQ

It’s not a backyard barbecue or beach party without great food and a pup or two. However, not all that food is safe for those dogs. One of those unsafe foods is BBQ sauce, so you must keep it out...

Can Dogs Eat BBQ Sauce

10 Best Dog Bowls for Large Dogs in 2025 – Reviews & Top Picks

It’s no secret that our large-breed doggies can be quite messy and need a lot more space at mealtime. If your dog is making sloppy messes or having trouble eating out of their current food bowl, you might want a...

dog drinking in the water bowl

9 Best Affordable Canned & Wet Dog Food in 2025 – Reviews & Top Picks

Did you know that the average American dog owner spends over $400 a year on food? In fact, dog owners spend more on food every year than they do on other pet-related expenses, such as vaccinations, grooming, pet insurance, training,...

person giving food to shih tzu dog

11 Best Large Breed Dog Foods in 2025 – Reviews & Top Picks

Large breed dogs need different nutrition than other breeds out there. They require more joint-supporting supplements, for instance, because their joints carry much more weight. Most large-breed dog foods are designed specifically to counteract these issues. However, this isn’t always...

labrador eating outside

Can Dogs Eat Kielbasa? Vet Reviewed Facts & FAQ

Kielbasa is a delicious sausage that many people love to eat; however, you should be careful when eating it around a dog. Kielbasa is not considered safe for animal consumption because it contains additives, seasonings, and other harmful components. Its...

Can Dogs Eat_kielbasa