Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

8 Common Puppy Illnesses & Diseases to Be Aware Of

cheerful young veterinary taking care and examining a beautiful pet dog french bulldog.

Puppies have so much growing up to do! Part of that process involves developing a healthy and strong immune system. As puppies age, they start to lose the protective antibodies that they acquired from their mother and begin to develop their own immune defenses.

However, this transition can make them vulnerable to sickness, especially those that aren’t fully vaccinated. The following list highlights the common illnesses and diseases that puppies can acquire.

divider dog paws 4 oct 2024

The 8 Common Puppy Illnesses & Diseases to Be Aware Of

1. Parvovirus (Parvo)

Parvovirus attacks the gastrointestinal system and causes signs like vomiting, bloody diarrhea, lethargy, anorexia, and dehydration. The virus is transmitted through contaminated feces, is highly contagious, and can prove fatal. The virus is also hardy in the environment and may survive for months or years. Ideally, puppies diagnosed with parvo should be hospitalized, as there is no cure for the disease, only supportive care.

mixed breed puppy with parvovirosis at the veterinary clinic
Image Credit: Todorean-Gabriel, Shutterstock

2. Distemper

Like parvo, distemper is a highly contagious and often fatal virus. It can attack the nervous, gastrointestinal, and respiratory systems, producing signs like seizures, head tilt, circling, fever, lethargy, coughing, and discharge from the eyes and nose. Some puppies develop thickened paw pads and may have dental abnormalities if they survive the disease. Other puppies may have neurological abnormalities that persist for life. Distemper virus can be transmitted in respiratory droplets from sneezing or coughing or from contaminated food and water bowls. There’s no cure but there is supportive care.


3. Canine Infectious Respiratory Disease (Kennel Cough)

Canine infectious respiratory disease is a common and easily transmissible respiratory virus among dogs. It may be caused by bacteria (like Bordetella bronchiseptica), a virus (like canine parainfluenza virus or canine coronavirus), or both. Most infections resolve on their own in 1–3 weeks, while more severe signs may require treatment like antibiotics, an anti-inflammatory, and a cough suppressant from your veterinarian. Severe cases of kennel cough may lead to pneumonia.

If your puppy is diagnosed with kennel cough, use a body harness instead of a collar so the pressure does not irritate their trachea.

Brindle Cane Corso standing on a grass field outdoors while wearing a harness
Image Credit: Eudyptula, Shutterstock

4. Leptospirosis

Leptospirosis is an infection caused by bacteria (Leptospira) that are shed through infected urine. It can be transmitted in contaminated water sources that are visited by wildlife and livestock, soil, bedding, or any surface containing infected urine. The infection attacks the kidneys and liver and is typically treated with antibiotics and aggressive fluid therapy in more severe cases.

Despite treatment, the disease can be fatal. It is also contagious to humans, making it a zoonotic disease. Care must be taken around puppies and dogs diagnosed with leptospirosis to avoid catching it. This includes wearing disposable gloves and washing your hands after cleaning up after your dog.


5. Adenovirus

Adenovirus is a virus that causes infectious canine hepatitis in puppies and dogs. It usually attacks the liver and is spread through contact with an infected animal or surface. Signs may include lethargy, inappetence, fever, vomiting, and diarrhea. There’s no cure, only supportive care. Unfortunately, the survival rate is low, only 1–30%.

sick weakened puppy lies in the arms of owner
Image Credit: Gladskikh Tatiana, Shutterstock

6. Rabies

Rabies is always fatal once clinical signs develop. This deadly virus is shed in saliva and transmitted through the bite of an infected animal. The signs may include behavioral changes, neurological abnormalities, hyperexcitability, or paralysis. Rabies is also contagious for humans, so if you’ve been bitten or scratched by a strange dog, you must seek medical care immediately.


7. Parasites

Internal and external parasites can affect puppies. Common internal parasites include roundworms, hookworms, stomach worms, tapeworms, giardia, coccidia, and heartworms. External parasites include fleas, ticks, mites, and lice.

owner applying flea and tick medicine to a dog
Image Credit: Nick Alias, Shutterstock

8. Vomiting and Diarrhea

Vomiting and diarrhea in a puppy can be caused by several underlying conditions that a veterinarian should evaluate. Common conditions include foreign bodies, toxins, stress, sudden diet changes, or bacterial, viral, or parasitic-related illnesses.

Dogster_Website dividers_v1_Jan 18 2024-03

How Can I Keep My Puppy Safe?

Start with the core vaccinations, such as DA2PPv, when your puppy reaches 6–8 weeks old.

This combination vaccine includes:
  • Distemper virus
  • Adenovirus type 2
    • This cross-protects against Adenovirus type 1, which causes infectious canine hepatitis; type 2 causes tracheobronchitis.
  • Parainfluenza (tracheobronchitis)
  • Parvovirus

To provide the best protection, it’s administered every 2–4 weeks until your puppy is 16–20 weeks old.

Another vaccine to consider is the one for canine infectious respiratory disease, especially the one caused by the bacterium Bordetella bronchiseptica. Puppies can get this starting at 8 weeks of age, especially if they’re exposed to other dogs. It’s also known as kennel cough or infectious tracheobronchitis and is common in dogs in kennels or boarding situations.

The leptospirosis vaccine can be started at 12 weeks of age. At this time, puppies can also be dewormed and started on flea-and-tick prevention to prevent infestations. Depending on the age of your puppy and your state laws, puppies can receive a rabies vaccine starting at 12–16 weeks of age. This would be best discussed with your veterinarian.

Ideally, your puppy should be fully vaccinated before interacting with other dogs at around 16 weeks of age. However, socialization in puppies is also crucial. If there are puppy socialization classes near you, you may be able to sign up for one that has puppies of similar ages and vaccine status. If you would like to bring your puppy out in public, you can do so by holding and carrying them around, to lessen the chance of disease transmission from other dogs.

If you’re unsure about your puppy’s health, growth, or vaccine schedule, its recommended that you contact your vet.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

Dogster_Website dividers_v1_Jan 18 2024-03

Conclusion

Puppies have an underdeveloped immune system, which can make them more susceptible to certain diseases. Taking precautions like vaccinating and supervising interactions with other dogs and places is crucial. Avoid places where the unknown vaccination status of dogs is frequent, such as dog parks, until your puppy is fully vaccinated.

Sources

Featured Image Credit: Hryshchyshen Serhii, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.


How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Can Bird Mites Live on Dogs? Vet-Verified Facts & FAQ

Bird mites are parasites found in wild birds and poultry. They are generally brown or grayish in color and turn darker after feeding....

Will a Cane Corso Be Good with My Cat? Socialization & Training Tips

The decision to bring a new pet into your home is a big one, especially when you already have other pets. Generally Cane...

Can You Warm Up Dog Food? Vet Approved Facts & Tips

Nobody likes cold, refrigerated food unless it’s meant to be cold. Like us, our dogs can be sensitive to chilled or cold food....

Will a Calming Collar Work for a Dog? Vet-Approved Facts

Dogs are usually fun-loving animals, but some dogs get overly excited or stressed out for one reason or another. For example, your dog...

More related

How Long Can My Dog Be in a Crate? Vet-Reviewed Factors & Alternatives

Crating your dog can be a helpful tool for training and providing a secure space for your pet. However, it’s essential to understand...

English Mastiff Price: How Much Do They Cost? 2026 Price Guide

The English Mastiff, or simply the Mastiff, is a type of working dog that was developed for fighting and guarding in England during...

Do Rhodesian Ridgebacks Like Water? Tips, Facts & FAQ

While every dog is different, the exotic Rhodesian Ridgeback isn’t a naturally water-loving pooch. Some of them love it if exposed to water...

8 Best Natural Dog Foods in 2026 – Reviews & Top Picks

As the pet food industry changes, so do the recipes that you see on shelves. Many contain artificial ingredients that could cause significant...

Keep reading

Nom Nom vs Spot & Tango: Which Fresh Dog Food is Better? 2026 Update

If you’re tired of researching dog food brands, don’t worry, you’re not alone. In the last 20 years, several new dog food manufacturers have entered the market to compete in the premium product category. Although the number of producers can...

Dogster_Dog Food Nom Nom VS Spot & Tango

6 Top Seeds for Dogs: Vet-Approved Healthy & Nutritious Options

Seeds are popular snacks, especially among health enthusiasts, due to their dense nutritional value. Naturally, some people wonder if they’re also safe for dogs. Many seeds are safe for dogs in moderation, but certain ones can be dangerous. Keep reading...

fresh sunflower seeds

Can Dogs Eat Acai Berries? Vet-Verified Info, Benefits & Risks

Pet owners are constantly on the lookout for foods that are safe, and beneficial, to their pets. With all the new superfoods entering our lives, it’s only natural for us to be curious as to whether we can share those...

Can Dogs Eat_acai berry

Can Dogs With Pancreatitis Eat Carrots? Vet-Verified Facts & FAQ

If your dog has just spent the last few days in intensive care due to pancreatitis and you’re worried about what you should and shouldn’t feed them, we’re here to help you out! There are types of foods your dog...

Can Dogs With Pancreatitis Eat Carrots

8 Amazing Benefits of Bone Broth for Dogs & Why We Love It (Vet Approved)

We want our pups to be as healthy as possible, so we make sure they eat nutritious dog food and exercise daily. But is there more we can do to ensure our dogs’ health and well-being? There is! One great...

bone broth bouillon in stainless steel pot

Can Dogs Eat Sour Patch Kids? Keep Your Dog Healthy!

If your dog begs for any food you put in your mouth, it probably won’t stop just because you’re eating something unsafe for them. That’s why it’s important to know which human snacks dogs can eat. Sour Patch Kids candy...

Can Dogs Eat_patch kids

Can Dogs Eat Cat Food? Vet-Verified Info & Safety Tips

When you live in a multi-pet household with dogs and cats, you’re probably used to having to keep your pets from eating each other’s food. Dogs and cats can eat many of the same foods, and a lot of the...

Can Dogs Eat Cat Food

Holistapet CBD Dog Treats Review 2026: Our Expert’s Opinion

Review Summary CBD has grown in popularity substantially over the past few years. While this holistic remedy was first touted for humans, there are now many different pet companies that offer CBD products as well. Holistapet is an established pet...

Holistapet CBD Dog Treats