Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Histiocytoma in Dogs? What It Is, Causes & Signs (Vet Answer)

Histiocytoma

Dogs can get all sorts of “lumps and bumps” that grow on them. Some occur in younger dogs, while most develop notice as dogs age. Many growths that develop on your dog may be harmless and nothing to worry about, but others may be aggressive cancers.

One of the more common types of growths we can see on the skin of dogs is a histiocytoma. It is a benign skin growth. Continue reading to learn more about this growth, what can cause it, and whether you should worry if your dog has one.

Dogster divider_v3_NEW_MAY_24_

What Is Histiocytoma in Dogs?

Histiocytomas are benign or non-malignant skin growths that are fairly common in dogs. Benign means the mass will not spread to other organ systems or aggressively invade surrounding tissues. Benign growths can continue to grow and become large, but this typically happens slowly. Metastasis, or the spread to other organ systems and aggressive invasion of surrounding tissues, does not occur with benign growths.

Histiocytomas typically go away with time as well. This is because the body’s immune system will eventually identify the growth as foreign and trigger an immune response to destroy the tumor.

Canine histiocytoma
Canine histiocytoma | Image By: self, Wikimedia Commons CC SA 3.0

What Are the Signs of a Histiocytoma?

Histiocytomas are most common in dogs less than a few years of age. However, they can occur at any age and anywhere on your dog’s skin. Typically, they will be rounded, button-like growths that are frequently pink and hairless. The growths come from the skin, not beneath the skin. They have a distinct appearance and border and are not associated with subcutaneous tissue or fat.

Histiocytomas usually are non-painful to the touch, have no odor, and will be freely moveable as the skin is moved beneath your fingers. Your dog may lick or chew at the mass simply because it is there, but the tumors do not tend to be itchy or cause irritation.

What Are the Causes of a Histiocytoma?

Histiocytomas are only associated with the skin. They originate from Langerhans cells, which are found in the epidermis. Langerhans cells help to capture foreign cells and “present” them to white blood cells for destruction. When the Langerhans cells group and grow together, they can form a tumor called a histiocytoma.

The good news is that these growths will eventually trigger your dog’s body to recognize them as foreign. Your dog’s immune system will eventually attack and destroy the tumors, resulting in their natural removal from the body.

Dogster divider_v2_NEW_MAY_24_

How Do I Care for a Dog With a Histiocytoma?

The first thing you want to do when you find a new mass or growth on your dog is to document where it is. Take a picture of the growth and circle it with a Sharpie so that it can easily be found by your veterinarian.

Next, take your dog to your veterinarian to try and diagnose the growth. While histiocytomas are benign, there are other skin growths that can have a similar appearance and be malignant. For instance, mast cell tumors and melanomas are two types of potentially aggressive skin growths that can look and feel exactly like a histiocytoma. Because of this, your veterinarian will want to get a diagnosis to determine if your dog has a malignant or a benign tumor.

Depending on the location of the histiocytoma and its size, your veterinarian may be able to aspirate the mass with a needle (abbreviated FNA for Fine Needle Aspirate), put the cells on a microscope slide, and send it to a pathologist for cytology. Cytology means that the pathologist will look at those cells under a microscope to try and determine what they are and if they are cancerous.

Your veterinarian may want to remove the entire mass with a quick surgery and then send the entire growth to a pathologist for histopathology. Histopathology is when a larger piece of tissue is evaluated to determine if it is cancerous.

Your veterinarian will walk you through both options and depending on the size and location of the mass, they will determine which will be a better option for your dog.

Did you know you can talk to a vet online? Click on the image or button below to schedule a call: PangoVet_Mention-in-Content Savings V1


Dogster divider_v2_NEW_MAY_24_

Frequently Asked Questions (FAQ)

Are Histiocytomas Considered a Cancer?

A histiocytoma is considered a type of tumor but is not cancerous. A tumor is a growth that can occur anywhere on the body from cells that divide and grow more than they should. However, not all tumors are considered cancerous.

A histiocytoma is considered benign. For a tumor to be considered cancerous, it needs to possess the capability to spread to other tissues and parts of the body.

Do I Need to Have My Dog’s Histiocytoma Removed?

Typically, histiocytomas will go away on their own. Once your dog’s immune system identifies them as foreign, it will eventually trigger an immune response to destroy the mass. However, depending on the location and size of the histiocytoma, your veterinarian may choose to completely remove it with surgery so that it can be sent to the lab for diagnosis.

Dogster divider_v3_NEW_MAY_24_

Summary

Histiocytomas are benign skin growths, most common in juvenile dogs. They will have a rounded, often pink, hairless appearance and be non-painful. Histiocytomas do not have to be surgically removed, though veterinarians will often remove them in order to obtain a diagnosis. Over time, histiocytomas will regress or shrink in size and eventually disappear completely.


Featured Image Credit: Histiocytoma | Image Credit: Joel Mills, Wikimedia Commons CC SA 3.0 Unported

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Will a Calming Collar Work for a Dog? Vet-Approved Facts

Dogs are usually fun-loving animals, but some dogs get overly excited or stressed out for one reason or another. For example, your dog...

How Big Does a Papillon Get? Average Growth & Weight Chart (Vet-Verified)

With their adorable and easily recognized butterfly ears, the Papillon has plenty of character packed into their small body. First favored by European...

How Safe Is Shipping Your Pet by Air? 2025 Facts & Statistics

Note: This article’s statistics come from third-party sources and do not represent the opinions of this website. Throughout the years, pets have moved...

BarkBox Subscription Review 2025: Keeping Your Dog Excited Month After Month

Subscriptions are a big part of our everyday life – from streaming services to ready-to-make meals delivered to our front doors. These products...

More related

10 Most Common Pet Insurance Claims: Facts & FAQ

More and more pet owners are realizing the benefits of pet insurance. Owners insured roughly 6.25 million pets in 2023, up 16.7% from...

Corgi Samoyed Mix: Info, Pictures, Care & More

Hybrid dogs have become popular over the last 20 years or so. The idea is to cross two purebred dogs to make one...

Skin Tags on Dogs (Plus Lipomas & Other Lumps): Our Vet Explains

Dogs can be prone to developing skin tags, just like people can. These benign growths may occur in areas where the skin rubs...

Berniefie (Bernese Mountain Dog Newfoundland Mix): Info, Pictures & More

Berniefies are mixes of Bernese Mountain Dogs and Newfoundlands. They’re likely to be enormous, and a Berniefie can weigh 90 to 150 pounds....

Keep reading

10 Best Dry Dog Foods in Canada in 2025: Reviews & Top Picks

Feeding your dog is one of the top priorities for all dog owners, and finding the perfect dog food that will keep your pup happy and in good health is essential! But whether you’re looking to switch your dog’s food...

labrador dog eating food indoor

Rachael Ray Dog Food Review 2025: Recalls, Pros & Cons

Review Summary Celebrity chef Rachael Ray has created a line of dog foods that feature some of her best recipes. This is a line of all-natural dog food that is considered to be high-quality and full of ingredients that can...

Dogster_Rachael Ray Dog Food Review

Do Dogs Like Dog Food? Canine Taste Buds Explained

We all know how excited our dogs can get at food time. They hear their kibble bag rustling or the sound of a food can opening and come running from wherever they are in the home to eat their meal....

bulldog eating fresh food

11 Best Senior Dog Foods in 2025 – Reviews & Top Picks

You’ll start to notice as your puppy grows to adulthood and beyond that, just like humans, their body starts to slow down and wear out. Once that starts happening, pet owners know that the senior years have started. It may...

dog eating

What Is Human-Grade Dog Food? Vet-Verified Facts About Ingredient Difference

Bringing a dog into your life is a special time for a family. Not only do you have a new friend, ally, and snuggle partner, but there is also another life you’re responsible for. This means ensuring your pets are...

The farmer's dog Turkey recipe fresh

Can Dogs Eat Veggie Straws? Vet-Reviewed Facts & FAQ

Veggie Straws are popular snacks because they are tasty and seem healthier than some other chip options on the market. However, this does not mean dogs should be indulging in this occasional snack with us. A couple of Veggie Straws...

Can Dogs Eat Veggie Straws

Can Dogs Eat Provolone Cheese? Vet-Verified Nutrition Facts & FAQ

Many foods aren’t necessarily toxic or poisonous to dogs, but they’re still not very good for them to eat. Cheese is one of those foods that doesn’t contain any toxic ingredients for dogs, but it’s not something that you should...

Can Dogs Eat Provolone Cheese

Can I Claim Dog Food on My Taxes in 2025? Pet-Related Deductions Guide

Tax season is never fun. We always hope there are things we can claim when filing. Surprisingly enough, there are several cases where the cost of your dog’s food may be tax-deductible. Usually, pet-related expenses are considered personal expenses, so...

woman computing taxes with her dog