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Histiocytoma in Dogs? What It Is, Causes & Signs (Vet Answer)

Written by: Dr. Kim Podlecki DVM (Veterinarian)

Last Updated on April 11, 2024 by Dogster Team


Histiocytoma in Dogs? What It Is, Causes & Signs (Vet Answer)


Dr. Kim Podlecki  Photo


Dr. Kim Podlecki

DVM (Veterinarian)

The information is current and up-to-date in accordance with the latest veterinarian research.

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Dogs can get all sorts of “lumps and bumps” that grow on them. Some occur in younger dogs, while most we will notice as dogs age. Many growths that develop on your dog may be harmless and nothing to worry about. While others may be aggressive cancers.

One of the more common types of growths we can see on the skin of dogs is a histiocytoma. It is a benign skin growth. Continue reading to learn more about what this growth is, what can cause it, and whether you should worry if your dog has one.


What Is Histiocytoma in Dogs?

Histiocytomas are benign, or non-malignant skin growths that are fairly common in dogs. Benign means that the mass will not spread to other organ systems or aggressively invade surrounding tissues. Benign growths can still continue to grow and become large, but this typically happens slowly. Metastasis, or spread to other organ systems and/or aggressive invasion of surrounding tissues, does not occur with benign growths.

Histiocytomas will typically go away with time as well. This is because the body’s immune system will eventually identify the growth as foreign, and trigger an immune response to destroy the tumor.

Canine histiocytoma
Canine histiocytoma | Image By: self, Wikimedia Commons CC SA 3.0

What Are the Signs of a Histiocytoma?

Histiocytomas are most common in dogs less than a few years of age. However, they can occur at any age and anywhere on the skin of your dog. Typically, they will be rounded, button-like growths that are frequently pink and hairless. The growths come from the skin, not beneath the skin. This means they will have a distinct appearance and border, and not be associated with the subcutaneous tissue and/or fat.

Histiocytomas usually are non-painful to the touch, have no odor, and will be freely moveable as the skin is moved beneath your fingers. Your dog may lick or chew at the mass simply because it is there, but the tumors themselves do not tend to be itchy or cause irritation.

What Are the Causes of a Histiocytoma?

Histiocytomas are only found associated with the skin. This is because they originate from something called Langerhan cells, which are found in the epidermis. Langerhan cells are found in the epidermis layer of the skin, and help to capture foreign cells and “present” them to white blood cells for destruction. When these Langerhan cells group and grow together, they can form a tumor called a histiocytoma.

The good news is that these growths will eventually trigger your dog’s body to recognize them as foreign. Your dog’s immune system will then eventually attack and destroy these tumors, resulting in their natural removal from the body.

How Do I Care for a Dog With a Histiocytoma?

The first thing you want to do when you find a new mass or growth on your dog is to document where it is. Take a picture of the growth and/or circle it with a sharpie, so that it can easily be found by your veterinarian.

Next, you want to have your dog seen by your veterinarian to try and diagnose the growth. While histiocytomas are benign, there are other skin growths that can have a similar appearance and be malignant. For instance, mast cell tumors and melanomas are two types of potentially aggressive skin growths that can look and feel exactly like a histiocytoma. Because of this, your veterinarian will want to get a diagnosis to determine if your dog has a malignant or a benign tumor.

Depending on the location of the histiocytoma and it is size, your veterinarian may be able to aspirate the mass with a needle (abbreviated FNA for Fine Needle Aspirate), put those cells on a microscope slide, and send it to a pathologist for cytology. Cytology means that the pathologist will look at those cells under a microscope to try and determine what they are and if they are cancerous.

Your veterinarian may just want to remove the entire mass with a quick surgery, and then send the entire growth into a pathologist for histopathology. Histopathology is when a larger piece of tissue is evaluated to determine if it is cancerous.

Your veterinarian will walk you through both options—again, depending on the size and location of the mass—and which will be a better option for your dog.

Frequently Asked Questions (FAQ)

Are Histiocytomas Considered a Cancer?

A histiocytoma is considered a type of tumor, but is not cancerous. A tumor is a growth that can occur anywhere on the body from cells that divide and grow more than they should. However, not all tumors are considered cancerous.

A histiocytoma is one type of tumor that is considered benign, or a tumor that won’t spread to other tissues or areas of the body. For a tumor to be considered cancerous, it needs to possess the capability to spread to other tissues and/or parts of the body.

Do I Need to Have My Dog’s Histiocytoma Removed?

Typically, histiocytomas will go away on their own. Once your dog’s immune system identifies them as foreign, it will trigger an immune response to eventually destroy the mass. However, depending on the location and size of the histiocytoma, your veterinarian may choose to completely remove it with surgery so that it can be sent to the lab for diagnosis.



Histiocytomas are benign skin growths, most common in juvenile dogs. They will have a rounded, often pink and hairless appearance and be non-painful. Histiocytomas do not have to be surgically removed, though veterinarians will often take it off in order to obtain a diagnosis. Over time, histiocytomas will regress or shrink in size and eventually disappear completely.

Featured Image Credit: Histiocytoma | Image Credit: Joel Mills, Wikimedia Commons CC SA 3.0 Unported

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