Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Histiocytoma in Dogs? What It Is, Causes & Signs (Vet Answer)

Histiocytoma

Dogs can get all sorts of “lumps and bumps” that grow on them. Some occur in younger dogs, while most develop notice as dogs age. Many growths that develop on your dog may be harmless and nothing to worry about, but others may be aggressive cancers.

One of the more common types of growths we can see on the skin of dogs is a histiocytoma. It is a benign skin growth. Continue reading to learn more about this growth, what can cause it, and whether you should worry if your dog has one.

Dogster divider_v3_NEW_MAY_24_

What Is Histiocytoma in Dogs?

Histiocytomas are benign or non-malignant skin growths that are fairly common in dogs. Benign means the mass will not spread to other organ systems or aggressively invade surrounding tissues. Benign growths can continue to grow and become large, but this typically happens slowly. Metastasis, or the spread to other organ systems and aggressive invasion of surrounding tissues, does not occur with benign growths.

Histiocytomas typically go away with time as well. This is because the body’s immune system will eventually identify the growth as foreign and trigger an immune response to destroy the tumor.

Canine histiocytoma
Canine histiocytoma | Image By: self, Wikimedia Commons CC SA 3.0

What Are the Signs of a Histiocytoma?

Histiocytomas are most common in dogs less than a few years of age. However, they can occur at any age and anywhere on your dog’s skin. Typically, they will be rounded, button-like growths that are frequently pink and hairless. The growths come from the skin, not beneath the skin. They have a distinct appearance and border and are not associated with subcutaneous tissue or fat.

Histiocytomas usually are non-painful to the touch, have no odor, and will be freely moveable as the skin is moved beneath your fingers. Your dog may lick or chew at the mass simply because it is there, but the tumors do not tend to be itchy or cause irritation.

What Are the Causes of a Histiocytoma?

Histiocytomas are only associated with the skin. They originate from Langerhans cells, which are found in the epidermis. Langerhans cells help to capture foreign cells and “present” them to white blood cells for destruction. When the Langerhans cells group and grow together, they can form a tumor called a histiocytoma.

The good news is that these growths will eventually trigger your dog’s body to recognize them as foreign. Your dog’s immune system will eventually attack and destroy the tumors, resulting in their natural removal from the body.

Dogster divider_v2_NEW_MAY_24_

How Do I Care for a Dog With a Histiocytoma?

The first thing you want to do when you find a new mass or growth on your dog is to document where it is. Take a picture of the growth and circle it with a Sharpie so that it can easily be found by your veterinarian.

Next, take your dog to your veterinarian to try and diagnose the growth. While histiocytomas are benign, there are other skin growths that can have a similar appearance and be malignant. For instance, mast cell tumors and melanomas are two types of potentially aggressive skin growths that can look and feel exactly like a histiocytoma. Because of this, your veterinarian will want to get a diagnosis to determine if your dog has a malignant or a benign tumor.

Depending on the location of the histiocytoma and its size, your veterinarian may be able to aspirate the mass with a needle (abbreviated FNA for Fine Needle Aspirate), put the cells on a microscope slide, and send it to a pathologist for cytology. Cytology means that the pathologist will look at those cells under a microscope to try and determine what they are and if they are cancerous.

Your veterinarian may want to remove the entire mass with a quick surgery and then send the entire growth to a pathologist for histopathology. Histopathology is when a larger piece of tissue is evaluated to determine if it is cancerous.

Your veterinarian will walk you through both options and depending on the size and location of the mass, they will determine which will be a better option for your dog.

Did you know you can talk to a vet online? Click on the image or button below to schedule a call: PangoVet_Mention-in-Content Savings V1


Dogster divider_v2_NEW_MAY_24_

Frequently Asked Questions (FAQ)

Are Histiocytomas Considered a Cancer?

A histiocytoma is considered a type of tumor but is not cancerous. A tumor is a growth that can occur anywhere on the body from cells that divide and grow more than they should. However, not all tumors are considered cancerous.

A histiocytoma is considered benign. For a tumor to be considered cancerous, it needs to possess the capability to spread to other tissues and parts of the body.

Do I Need to Have My Dog’s Histiocytoma Removed?

Typically, histiocytomas will go away on their own. Once your dog’s immune system identifies them as foreign, it will eventually trigger an immune response to destroy the mass. However, depending on the location and size of the histiocytoma, your veterinarian may choose to completely remove it with surgery so that it can be sent to the lab for diagnosis.

Dogster divider_v3_NEW_MAY_24_

Summary

Histiocytomas are benign skin growths, most common in juvenile dogs. They will have a rounded, often pink, hairless appearance and be non-painful. Histiocytomas do not have to be surgically removed, though veterinarians will often remove them in order to obtain a diagnosis. Over time, histiocytomas will regress or shrink in size and eventually disappear completely.


Featured Image Credit: Histiocytoma | Image Credit: Joel Mills, Wikimedia Commons CC SA 3.0 Unported

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Shar Pei Mastiff Mix Breed: Info, Pictures, Care & More

The Shar Pei breed has wrinkled coats and equally adorable wrinkly faces. These distinctive features of the breed make them recognizable, and many...

Can Dogs Eat Jalapeños? Vet-Reviewed Health Facts

We humans have a much more varied diet than any of our four-legged companions. Our pantries and refrigerators are full of foods that...

Are Dogs Allowed on Destin Beaches in 2025? Rules & Location Guide

During the warmer months, it’s difficult to keep our minds off of the beach—especially those pristine beaches in Florida. Destin, Florida is among...

How Much Exercise Do Golden Retrievers Need? Vet-Reviewed Facts & FAQ

Every dog is a little different in terms of exercise needs. Some tend to be extremely hyper and ready for action, while others...

More related

How to Correctly Measure a Dog for a Muzzle: 13 Important Tips & FAQs

As a dog owner, you may sometimes find yourself in situations where using a muzzle is necessary for the safety of yourself, your...

Icelandic Sheepdog: Breed Info, Pictures, Facts & Traits  

The Icelandic Sheepdog is a spitz-type breed whose ancestors first made their way to Iceland by sea about 1,100 years ago with Norse...

Can Dogs Eat Cayenne Peppers? Vet-Approved Advice

Cayenne peppers, also colloquially called chili peppers, are a delicious spicy fruit, but they aren’t a suitable treat for your pup. What happens...

What Happens to Police Dogs When They Retire? Facts About Canine Retirement

Dogs play a big part in helping many local or national police forces maintain order and the rule of law. They even serve...

Keep reading

10 Best Rawhide Alternatives for Dogs In 2025 – Reviews & Top Picks 

While some owners swear by rawhide chews, because they are especially good at keeping power chewers busy for hours at a time, many owners refuse to use them. Some manufacturers use chemicals like bleach and hydrogen peroxide to remove the...

A dog and it's antler A brown and white dog lying on it's bed chewing on a deer antler

Why Is My Dog Gaining Weight But Not Eating More? 10 Vet-Reviewed Reasons

Did you know that 59% of dogs in the United States are considered overweight or obese1? It’s true, and extra pounds put dogs at risk of developing debilitating health conditions like arthritis and reduce their lifespan. However, if your dog...

dog sitting on weighing scale

How to Save Money on Dog Food in 4 Ways (2025 Guide)

I am a dog sitter, which means I’m surrounded by happy pups 24/7. Things get wild at mealtime — something my dog, Riggins, will not allow to be missed. In fact, Riggins takes his mealtimes so seriously, he will start...

Maltese dog sitting on a picnic blanket

Can Dogs Eat Butternut Squash? Vet-Approved Facts & FAQ

Dogs have no qualms about trying anything that falls off our plate, but you might be wondering what’s healthy for them and what’s not. For instance, you’re eating squash and your dog scarfs down some—is that OK or something to...

Can Dogs Eat_Butternut Squash

10 Best Grain-Free Dog Food in Australia in 2025 – Reviews & Top Picks

Looking for the best grain-free dog food in Australia? Look no further! We’ve got you covered with our comprehensive reviews of the top grain-free dog foods on the market. Be sure to speak with your veterinarian if grain-free is required...

Ziwi Peak Air-Dried Dog Food new

10 Best Chicken-Free Dog Foods in 2025: Reviews & Top Picks (Vet-Approved)

Chicken is commonly found in many pet foods. It’s an inexpensive way to add lean protein and healthy nutrients to your dog’s food to keep them at their best. However, sometimes a chicken-free diet is necessary for your pup. If...

dog eating in a food bowl

Can Dogs Eat Jasmine Rice? Vet-Reviewed Facts & Tips

Every dog enjoys the occasional treat added to dog food. Dog owners love to spoil their canine kiddos with extra treats, as they worry about them getting bored eating the same thing day in and day out. However, you should...

Can Dogs Eat Jasmine Rice

8 Best Puppy Foods for Medium Breeds in 2025 – Reviews & Top Picks

Shopping for the right food for your new puppy can be a bit overwhelming. Any dog lover knows that the food choices on the market today are seemingly endless. Even if you’re a brand-new dog owner, all you have to...

cocker spaniel in grass field