Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Histiocytoma in Dogs? What It Is, Causes & Signs (Vet Answer)

Histiocytoma

Dogs can get all sorts of “lumps and bumps” that grow on them. Some occur in younger dogs, while most develop notice as dogs age. Many growths that develop on your dog may be harmless and nothing to worry about, but others may be aggressive cancers.

One of the more common types of growths we can see on the skin of dogs is a histiocytoma. It is a benign skin growth. Continue reading to learn more about this growth, what can cause it, and whether you should worry if your dog has one.

Dogster divider_v3_NEW_MAY_24_

What Is Histiocytoma in Dogs?

Histiocytomas are benign or non-malignant skin growths that are fairly common in dogs. Benign means the mass will not spread to other organ systems or aggressively invade surrounding tissues. Benign growths can continue to grow and become large, but this typically happens slowly. Metastasis, or the spread to other organ systems and aggressive invasion of surrounding tissues, does not occur with benign growths.

Histiocytomas typically go away with time as well. This is because the body’s immune system will eventually identify the growth as foreign and trigger an immune response to destroy the tumor.

Canine histiocytoma
Canine histiocytoma | Image By: self, Wikimedia Commons CC SA 3.0

What Are the Signs of a Histiocytoma?

Histiocytomas are most common in dogs less than a few years of age. However, they can occur at any age and anywhere on your dog’s skin. Typically, they will be rounded, button-like growths that are frequently pink and hairless. The growths come from the skin, not beneath the skin. They have a distinct appearance and border and are not associated with subcutaneous tissue or fat.

Histiocytomas usually are non-painful to the touch, have no odor, and will be freely moveable as the skin is moved beneath your fingers. Your dog may lick or chew at the mass simply because it is there, but the tumors do not tend to be itchy or cause irritation.

What Are the Causes of a Histiocytoma?

Histiocytomas are only associated with the skin. They originate from Langerhans cells, which are found in the epidermis. Langerhans cells help to capture foreign cells and “present” them to white blood cells for destruction. When the Langerhans cells group and grow together, they can form a tumor called a histiocytoma.

The good news is that these growths will eventually trigger your dog’s body to recognize them as foreign. Your dog’s immune system will eventually attack and destroy the tumors, resulting in their natural removal from the body.

Dogster divider_v2_NEW_MAY_24_

How Do I Care for a Dog With a Histiocytoma?

The first thing you want to do when you find a new mass or growth on your dog is to document where it is. Take a picture of the growth and circle it with a Sharpie so that it can easily be found by your veterinarian.

Next, take your dog to your veterinarian to try and diagnose the growth. While histiocytomas are benign, there are other skin growths that can have a similar appearance and be malignant. For instance, mast cell tumors and melanomas are two types of potentially aggressive skin growths that can look and feel exactly like a histiocytoma. Because of this, your veterinarian will want to get a diagnosis to determine if your dog has a malignant or a benign tumor.

Depending on the location of the histiocytoma and its size, your veterinarian may be able to aspirate the mass with a needle (abbreviated FNA for Fine Needle Aspirate), put the cells on a microscope slide, and send it to a pathologist for cytology. Cytology means that the pathologist will look at those cells under a microscope to try and determine what they are and if they are cancerous.

Your veterinarian may want to remove the entire mass with a quick surgery and then send the entire growth to a pathologist for histopathology. Histopathology is when a larger piece of tissue is evaluated to determine if it is cancerous.

Your veterinarian will walk you through both options and depending on the size and location of the mass, they will determine which will be a better option for your dog.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your dog — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

Dogster divider_v2_NEW_MAY_24_

Frequently Asked Questions (FAQ)

Are Histiocytomas Considered a Cancer?

A histiocytoma is considered a type of tumor but is not cancerous. A tumor is a growth that can occur anywhere on the body from cells that divide and grow more than they should. However, not all tumors are considered cancerous.

A histiocytoma is considered benign. For a tumor to be considered cancerous, it needs to possess the capability to spread to other tissues and parts of the body.

Do I Need to Have My Dog’s Histiocytoma Removed?

Typically, histiocytomas will go away on their own. Once your dog’s immune system identifies them as foreign, it will eventually trigger an immune response to destroy the mass. However, depending on the location and size of the histiocytoma, your veterinarian may choose to completely remove it with surgery so that it can be sent to the lab for diagnosis.

Dogster divider_v3_NEW_MAY_24_

Summary

Histiocytomas are benign skin growths, most common in juvenile dogs. They will have a rounded, often pink, hairless appearance and be non-painful. Histiocytomas do not have to be surgically removed, though veterinarians will often remove them in order to obtain a diagnosis. Over time, histiocytomas will regress or shrink in size and eventually disappear completely.


Featured Image Credit: Histiocytoma | Image Credit: Joel Mills, Wikimedia Commons CC SA 3.0 Unported

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Frustration-Elicited Aggression in Dogs: Vet-Verified Info & How to Stop it

Even the most sweet-natured dog can suffer bouts of aggression from time to time. While this is normal, it shouldn’t be ignored, as...

Dog Kennels vs. Crates: Vet-Verified Differences (With Info & Pictures)

Whether you’re bringing home a new puppy, you have an old dog, or anything in between, we all know that finding ways to...

Dogster Photo Contest: Dogs of the Week Winners (October 23, 2025)

Every week our team gets the privilege of sorting through our readers photos to choose what dogs will win this weeks contest! See...

Health Problems in Shih Tzus: 11 Common Issues to Watch For

Shih Tzus are very popular family dogs thanks to their fun-loving, spirited, and affectionate natures. They bring a lot of joy and countless...

More related

How to Get Dog Poop Smell & Stains Out of Hardwood Floors: 4 Effective Ways

Our hardwoods are precious. They can be some of the most prized possessions in your household. Not only are hardwood floors easy to...

Can Dogs Eat Ramen Noodles? Vet-Verified Nutrition Facts & Risks

If you’re a fan of ramen noodles and wondering whether you can share a bowl with your dog, sorry, but no. Instant ramen...

American vs European Great Dane: Which Pet Should You Choose?

American and European Great Danes are extremely similar animals. Both are large dogs, love their family members, get along well in social settings,...

Chinese Shar Pei Dog Breed: Info, Pictures, Care, Traits & More

The Shar Pei is an ancient Chinese breed with bountiful wrinkles and a chubby mouth. However, don’t be swayed by their adorable looks;...

Keep reading

10 Best Fresh Dog Food Delivery Services in 2026 – Reviews & Top Picks

Dog food subscription and delivery services are a convenient way to buy food for your pet, and while they are generally slightly more expensive, they do take most of the hassle out of shopping for your pal’s meals. Luckily, there...

Finny opening the door with the farmers dog delivery

10 Best Dog Foods for Active Dogs in 2026 – Reviews & Top Picks

If you have an active dog, you may have found that you struggle with keeping weight on your dog, no matter how much you feed them. Some breeds also struggle to maintain their body weight, especially while they’re young. A...

labrador retriever eating dog food

11 Best Dog Foods for Cane Corso Puppies in 2026 – Reviews & Top Picks

Cane Corsos are huge dogs that take a lot of time to grow. Therefore, you’ll be feeding your Cane Corso puppy food for much longer than most other breeds who eat puppy food. They’re simply puppies for longer. Therefore, what...

cane corso puppy

8 Best Dog Foods for Weight Loss in 2026 – Reviews & Top Picks

Most dogs love to eat and we love to feed them! Giving them food and treats that we know that they enjoy makes us happy. The downside is that dogs can gain weight if we aren’t careful with their diets....

Shetland sheepdog eats food from a food bowl

Can Dogs Have Pumpkin Spice? Vet-Verified Health & Nutrition Guide

Fall brings with it the advent of pumpkin spice everything—pumpkin spice lattes, pumpkin spice cookies and bread, pumpkin spice scented candles, and more! There’s really no better way to get into the fall season than with some pumpkin spice. But...

pumpkin spice

Can Dogs Eat Hush Puppies? Vet-Reviewed Facts, Risks & Alternatives

While you shouldn’t need to rush your dog to the vet if they eat a single hush puppy, that doesn’t mean dogs should eat these cornmeal snacks. There are plenty of reasons that you shouldn’t give hush puppies to your...

Can Dogs Eat Hush Puppies

Can Dogs Eat Ravioli? Vet-Verified Facts & Safety Guide

Americans love their pets, which is why they’re willing to dish out an estimated $150.6 billion on them. Roughly $70 million goes toward food. Nevertheless, we still bring home doggy bags and give them table scraps. The recent pet humanization...

Can Dogs Eat_ravioli

Can Dogs Eat Peanuts? Vet-Approved Nutrition Guide

Our canine companions love peanut butter. There are even photography books dedicated entirely to pictures of dogs who love eating this tasty and beloved treat! Dog parents love giving their pups peanut butter, too, especially as a means of getting...

Can Dogs Eat Peanuts