Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Histiocytoma in Dogs? What It Is, Causes & Signs (Vet Answer)

Share

Histiocytoma

Dogs can get all sorts of “lumps and bumps” that grow on them. Some occur in younger dogs, while most develop notice as dogs age. Many growths that develop on your dog may be harmless and nothing to worry about, but others may be aggressive cancers.

One of the more common types of growths we can see on the skin of dogs is a histiocytoma. It is a benign skin growth. Continue reading to learn more about this growth, what can cause it, and whether you should worry if your dog has one.

Dogster divider_v3_NEW_MAY_24_

What Is Histiocytoma in Dogs?

Histiocytomas are benign or non-malignant skin growths that are fairly common in dogs. Benign means the mass will not spread to other organ systems or aggressively invade surrounding tissues. Benign growths can continue to grow and become large, but this typically happens slowly. Metastasis, or the spread to other organ systems and aggressive invasion of surrounding tissues, does not occur with benign growths.

Histiocytomas typically go away with time as well. This is because the body’s immune system will eventually identify the growth as foreign and trigger an immune response to destroy the tumor.

Canine histiocytoma
Canine histiocytoma | Image By: self, Wikimedia Commons CC SA 3.0

What Are the Signs of a Histiocytoma?

Histiocytomas are most common in dogs less than a few years of age. However, they can occur at any age and anywhere on your dog’s skin. Typically, they will be rounded, button-like growths that are frequently pink and hairless. The growths come from the skin, not beneath the skin. They have a distinct appearance and border and are not associated with subcutaneous tissue or fat.

Histiocytomas usually are non-painful to the touch, have no odor, and will be freely moveable as the skin is moved beneath your fingers. Your dog may lick or chew at the mass simply because it is there, but the tumors do not tend to be itchy or cause irritation.

What Are the Causes of a Histiocytoma?

Histiocytomas are only associated with the skin. They originate from Langerhans cells, which are found in the epidermis. Langerhans cells help to capture foreign cells and “present” them to white blood cells for destruction. When the Langerhans cells group and grow together, they can form a tumor called a histiocytoma.

The good news is that these growths will eventually trigger your dog’s body to recognize them as foreign. Your dog’s immune system will eventually attack and destroy the tumors, resulting in their natural removal from the body.

Dogster divider_v2_NEW_MAY_24_

How Do I Care for a Dog With a Histiocytoma?

The first thing you want to do when you find a new mass or growth on your dog is to document where it is. Take a picture of the growth and circle it with a Sharpie so that it can easily be found by your veterinarian.

Next, take your dog to your veterinarian to try and diagnose the growth. While histiocytomas are benign, there are other skin growths that can have a similar appearance and be malignant. For instance, mast cell tumors and melanomas are two types of potentially aggressive skin growths that can look and feel exactly like a histiocytoma. Because of this, your veterinarian will want to get a diagnosis to determine if your dog has a malignant or a benign tumor.

Depending on the location of the histiocytoma and its size, your veterinarian may be able to aspirate the mass with a needle (abbreviated FNA for Fine Needle Aspirate), put the cells on a microscope slide, and send it to a pathologist for cytology. Cytology means that the pathologist will look at those cells under a microscope to try and determine what they are and if they are cancerous.

Your veterinarian may want to remove the entire mass with a quick surgery and then send the entire growth to a pathologist for histopathology. Histopathology is when a larger piece of tissue is evaluated to determine if it is cancerous.

Your veterinarian will walk you through both options and depending on the size and location of the mass, they will determine which will be a better option for your dog.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your dog — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

Dogster divider_v2_NEW_MAY_24_

Frequently Asked Questions (FAQ)

Are Histiocytomas Considered a Cancer?

A histiocytoma is considered a type of tumor but is not cancerous. A tumor is a growth that can occur anywhere on the body from cells that divide and grow more than they should. However, not all tumors are considered cancerous.

A histiocytoma is considered benign. For a tumor to be considered cancerous, it needs to possess the capability to spread to other tissues and parts of the body.

Do I Need to Have My Dog’s Histiocytoma Removed?

Typically, histiocytomas will go away on their own. Once your dog’s immune system identifies them as foreign, it will eventually trigger an immune response to destroy the mass. However, depending on the location and size of the histiocytoma, your veterinarian may choose to completely remove it with surgery so that it can be sent to the lab for diagnosis.

Dogster divider_v3_NEW_MAY_24_

Summary

Histiocytomas are benign skin growths, most common in juvenile dogs. They will have a rounded, often pink, hairless appearance and be non-painful. Histiocytomas do not have to be surgically removed, though veterinarians will often remove them in order to obtain a diagnosis. Over time, histiocytomas will regress or shrink in size and eventually disappear completely.


Featured Image Credit: Histiocytoma | Image Credit: Joel Mills, Wikimedia Commons CC SA 3.0 Unported

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.




How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Ask Dr. Paola- Help! My Dog’s Sleeping Habits Have Changed! (May 18, 2026)

Welcome to our “Ask Dr. Paola” series, where every Monday we bring expert advice straight from Dr. Paola Cuevas (MVZ) to help our...

The Crate Setup Most Dog Owners Get Wrong (And How To Fix It!)

Most people assume that if their dog hates the crate, the crate is the problem. So they try a bigger one, a different...

1,500 Beagles Rescued from Wisconsin Lab Farm – Here’s Where They’re Going

You may remember that a few weeks ago, we reported on a tense situation at Ridglan Farms, Wisconsin, a facility infamous for housing...

Dogster’s Weekly Photo Contest Winners: Window Watchers (May 11, 2026)

Every week our team gets the privilege of sorting through our readers photos to choose what dogs will win this weeks contest! See...

More related

Can Humans Use Dog Shampoo? Vet-Approved Safety and Efficacy

Anyone who purchases dog shampoo might find themselves wondering whether it can be used on human hair. This question can arise out of...

7 Warning Signs That Your Dog Is Obese: Vet-Approved Advice

Obesity in pets is a big problem. It’s suggested that over half of all cats and dogs in the United States are overweight.1...

Vietnamese Hmong Dog Breed: Info, Pictures, Care & More

If you’ve ever seen a Vietnamese Hmong dog, also known as the Hmong Docked Tail Dog, you have now realized how special and...

How Dangerous Are Akitas? Vet-Approved Tips, Socialization & FAQ

It’s easy to be enchanted by the Akita’s strength, beauty, and oddly adorable curled tail, but you should never rely on looks alone...

Keep reading

Can Dogs Eat Teddy Grahams? Vet-Approved Facts & FAQ

Before changing your dog’s/ cat’s diet or introducing new ingredients or supplements that they haven’t eaten before, especially when it comes to human food, make sure to consult your veterinarian first. Every dog/cat is different and requires an individual approach...

Can Dogs Eat Teddy Grahams

11 Best Dog Foods for Labs in 2026 – Reviews & Top Picks

When it comes to canine nutrition, we are learning how vital it is to our beloved dog’s overall health to feed them the very best. If you have a large breed like a Labrador, providing a well-balanced diet is essential...

Labrador dog eating

Orijen Dog Food vs Blue Buffalo Dog Food: 2026 Comparison, Pros & Cons

With so many dog food options on the market, it’s easy to walk away with your hands empty and your head buzzing. If you’ve been buying dog food for some time or have recently adopted a puppy and have been...

Dogster_Dog Food Orijen VS Blue Buffalo

Kirkland vs Blue Buffalo Dog Food Comparison 2026: Which Is Better?

Choosing the right food for your dog should be simple, right? We get it—with countless brands, endless ingredient lists, and ever-evolving advice on what’s best for each dog, it’s easy to feel overwhelmed. What’s truly healthy for our furry friends?...

Dogster_Dog Food Kirkland VS Blue Buffalo

Castor & Pollux Dog Food Review 2026: Pros, Cons, Recalls, and FAQ

Review Summary Please note that several Castor & Pollux products are currently unavailable. At this time, we are unsure whether these items have been fully discontinued, are experiencing supply issues, or if there is another reason for their absence. We...

Dogster_Castor & Pollux Dog Food Review

10 Best Dog Foods for Huskies to Gain Weight in 2026: Reviews & Top Picks

It can be stressful to have a dog that is underweight, and Huskies are a breed that are particularly prone to this because of their high activity level. It can also be difficult to determine your Husky’s body composition due...

young siberian husky eating

Eukanuba Dog Food Review 2026: Pros, Cons & Recalls

Eukanuba Dog Food Review Summary Giving your dog all the nutrients that they need for a healthy and active life is the number-one goal of any dog owner. There are countless dog food brands on the market, making finding the...

Dogster_Eukanuba Dog Food Review

Ollie Fresh Dog Food Review 2026: Pros, Cons & Final Verdict

Ollie Pets delivers fresh premium dog food straight to your door. All the recipes were crafted by experts in the field and contain very nutrient-dense ingredients. If you’re looking to make mealtimes more convenient, you’ll want to consider Ollie. Once...

DOG SAPR OLLIE NEW

Love Dogs? So Do We! Join the Dogster Community

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.




Sign up for the Dogster Email Newsletter