Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Can Dogs Take Rimadyl Long Term? Our Vet Discusses Health & Safety Facts

Owner giving medicine in a pill to his dog

Your veterinarian has prescribed your dog Rimadyl for arthritis pain, and your dog is doing well. That’s great, but can you give Rimadyl in the long term, or is the risk of side effects too high? Let’s look at what can happen to your dog on long-term medication like Rimadyl.

divider dog paws 2 oct 2024

Can Dogs Take Rimadyl Long Term?

For many dogs, the answer is a resounding yes; they can take Rimadyl long-term. Your veterinarian will need to perform regular monitoring, generally in the form of routine blood work, to look for any abnormalities that could develop with chronic medication usage.

If your dog has underlying liver or kidney disease or any other chronic disease, your veterinarian will likely look at using an alternative to Rimadyl. Over time, this medication can also cause liver and kidney changes, which is why blood work should be performed, usually at least one to two times per year. (Some pets may need blood work as frequently as every three months.)

Before giving any new medication to your dog, we recommend you consult a veterinarian for the best advice on which would be the best treatment for your pup.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your dog — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

What Is Rimadyl?

Rimadyl is a non-steroidal anti-inflammatory drug or NSAID. Rimadyl is a brand name for carprofen, which can also be sold as Vetprofen, Novox, quellin, and many more medications.

Many veterinarians prescribe Rimadyl for chronic pain related to osteoarthritis. The medication works to inhibit cyclooxygenase (COX) enzymes that are part of the inflammatory cascade that can lead to worsening pain and even further cartilage damage. By inhibiting COX, you can help inhibit inflammation.

Rimadyl is typically administered as a chewable tablet, but your veterinarian might also administer it as an injection. The Rimadyl may be given every 12 or 24 hours, depending on the dosage.

Side Effects of Rimadyl

The liver primarily metabolizes Rimadyl. After the liver processes it, it is eliminated via the intestines and the kidneys.

The more common side effects of Rimadyl include gastrointestinal issues, including:
  • Vomiting
  • Diarrhea
  • Inappetence

Unfortunately, there is a risk of more severe side effects, including gastric ulcers and bleeding. Liver and kidney damage are also possible, so regular blood work monitoring is essential.

Some things to watch for include:
  • Jaundice or yellowing of the gums or sclera (the typically white part of the eyes)
  • Dark or bloody stool or vomit
  • Polyuria (excessive urination)
  • Polydipsia (excessive drinking)
  • Weakness or collapse

Some Labrador Retrievers seem to be especially sensitive to the effects of Rimadyl and may develop liver damage.

Rimadyl should never be administered with other NSAIDs or steroids. This combination of medications can increase the risk for GI bleeding.

labrador retriever dog lying on the floor looking sad or sick
Image Credit: Jaromir Chalabala, Shutterstock

Monitoring a Dog on Rimadyl

Typically, your veterinarian will need to perform a chemistry panel on your dog’s blood several times per year to monitor for biochemical changes.

They're mainly looking at several liver and kidney-associated values, such as:
  • Alanine transferase
  • Alkaline phosphatase
  • Blood urea nitrogen
  • Creatinine
  • Albumin
  • Bilirubin

Your veterinarian will likely also suggest period urinalysis tests. These tests ensure that the kidneys are concentrating appropriately, that there’s no protein in the urine, and that there is no evidence of a urinary tract infection.

Alternatives to Rimadyl for Dogs

There are other NSAIDs that your veterinarian may prescribe as an alternative to Rimadyl.

These other NSAIDs include:
  • Galliprant (grapiprant)
  • Metacam (meloxicam)
  • Deramaxx (deracoxib)
  • Previcox (firocoxib)

You should never give Rimadyl in addition to one of these medications. Instead, your veterinarian will recommend a wash-out period between medications.

Your veterinarian might also recommend other medications to use with Rimadyl to improve overall pain control.

young woman talking to the vet
Image Credit: SeventyFour, Shutterstock
These medications and supplements include:
  • Gabapentin
  • Amantadine
  • Fish oils
  • Adequan
  • Glucosamine

Librela is a newer medication for controlling arthritis pain in dogs. If your dog is a candidate, your veterinarian can administer a monthly injection. It tends to have minimal side effects, such as increasing the possibility of certain infections.

divider dog paws 2 oct 2024

Frequently Asked Questions (FAQ)

How long does it take for Rimadyl to leave a dog’s system?

Rimadyl generally lasts 12 to 24 hours, depending on the dose. Given its short half-life, it should be entirely out of your dog’s system within a few days.

person giving tick and flea medicine to a white maltese dog
Image Credit: Tanya Dol, Shutterstock

How long does it take Rimadyl to start working?

Rimadyl starts to work pretty quickly, generally within one to three hours. Like with many medications, it can take several days to see the maximum benefits of using the medication, especially in cases of chronic pain.

divider dog paws 2 oct 2024

Conclusion

Rimadyl tends to be an effective and safe medication for many dogs. That said, your veterinarian must monitor your dog’s blood work regularly to ensure it does not develop liver or kidney changes.

See also: 


Featured Image Credit: Creative Cat Studio, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.


How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Do Dogs Know When You’re Sad? Interesting Facts & Tips

If you aren’t a dog lover, you may not understand the connection between an owner and their canine best friend. Dogs are often...

6 Best Dog Poop Bag Holders in 2026 – Reviews & Top Picks

Having a dog poop bag holder comes in handy when you need to easily access dog poop bags when you are out traveling...

Why Does Kodah Drown His Toys? Fred the Bully

Hi, I’m Dr. Karyn! Read my introduction to learn more about me and my five funny dogs, Poppy, Bailey, Kodah, Ned, and Fred....

Can Dogs Eat Spaghetti Sauce? Vet-Verified Nutrition Facts & Better Alternatives

Pasta night is a tradition in many homes, so there’s a fair chance our family dogs will come across at least a little...

More related

When Do Golden Retrievers Start to Calm Down? Useful Facts

Golden Retrievers are among the most popular dog breeds in the United States and the United Kingdom. They always rank at the top...

Ruff Greens Premium Canine Supplements Review 2026: An Expert’s Breakdown

Lots of people take supplements to boost their overall health, whether in pill form or powder form mixed into a glass of water....

What Dog Shampoos Do Groomers Use? Recommendations & FAQ

Did you ever wonder how dog groomers manage to consistently get such nice results no matter the kind of dog or coat they...

My Dog Is Bleeding After Birth: Vet-Explained Risks, Signs & Next Steps

When a dog gives birth, their human carer usually puts a lot of thought into getting ready for the delivery and where the...

Keep reading

9 Best High Fiber Dog Foods for Anal Gland Problems in 2026 – Reviews & Top Picks

Dealing with anal gland problems in your dog can be smelly, gross, and frustrating. Anal gland issues are uncomfortable for your dog, and some even develop abscesses and other serious infections related to anal gland problems. If you see your...

Ginger dog eating

Evermore Dog Food Review 2026: Pros, Cons & Verdict: An Expert’s Breakdown

*Free shipping for subscriptions Human-grade, frozen-fresh, hand-made dog food produced by a small-scale, family-run, ethically-minded company? Gently cooked, highly nutritious, and delicious recipes that satisfy my dog’s appetite and keep him healthy? Count us in! My dog Leo and I...

DOG_SAPR_Evermore Dog Food

Top 10 Most Popular Dog Treat Brands in 2026 – Reviews & Top Picks

Dog owners know how much their pets love treats. What could be better than a delicious treat to reward your dog for a job well done? There are many different flavors, textures, and sizes of dog treats, as well as...

jack russell terrier having treats

Authority Puppy Food Review 2026: Recalls, Pros & Cons

Review Summary A new puppy can bring a lot of excitement into your life! Along with the adorable pictures and play, there are some tough questions, like what you will be feeding your new bundle of fur. If you are...

Dogster_Authority Puppy Food Review

Can Dogs Eat Sage? Vet Approved Facts & FAQ

Sage is a commonly used herb in the kitchen that flavors foods and is also used in essential oils, creams, ointments, and medicines. If you cook with sage or have it growing abundantly in your garden, you may wonder if...

Can Dogs Eat Sage

10 Best Puppy Foods in 2026 – Reviews & Top Picks

It’s essential that you provide your puppy with food specifically made for its stage of life. By providing your puppy with puppy-specific food, it’s much more likely to grow healthily and happily. Of course, it’s critical to select puppy food...

jack russell terier puppy eating food from bowl

Best Canned Pumpkin for Dogs: Our Top 6 Picks in 2026

Pumpkin isn’t just an autumn treat anymore—especially when it comes to your dog. Canned pumpkin is a popular treat and dog food topper, and many dogs can’t get enough of it! It’s also a healthy superfood that has many benefits...

Dog beside Pumpkin

Can Dogs Eat Rice? Vet-Verified Nutrition Facts, Benefits & Risks

Rice is a staple food found in almost every kitchen worldwide, and there are many different varieties to choose from! If your dog is eyeing your rice-based meal, you might wonder if it’s safe for your dog to eat rice....

Can Dogs Eat Rice