Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

NSAID Panel Blood Test For Dogs: Our Vet Explains Necessity & Frequency

blood samples of a dog for lab testing

Non-steroidal anti-inflammatories (NSAIDs) are used to treat various issues in canines, from short-lived treatment like spay surgery pain to long-term use for osteoarthritis. For most dogs, NSAIDs provide them with pain-free mobility, but using them in the long run can come at a cost. That’s why NSAID panels are so vital.

These blood tests help check the effects that the prescribed NSAID may be having on the dog’s major organs. As a rule, they should be performed before starting treatment and then periodically throughout the process. The frequency will depend on the dog and the situation.

divider single dog paw oct 2024

What Is an NSAID Panel for Dogs?

NSAIDs can work wonders at reducing inflammation and pain from all sorts of ailments. Unfortunately, they may also be negatively affecting certain parts of the body. The digestive system, kidneys, liver, and blood cells are the most common victims.

Keep in mind that side effects are more likely to occur at high doses and when taken with other medications, but they can still happen to an otherwise healthy dog taking only normal levels of NSAIDs.

To monitor these targeted organs, periodically doing an NSAID blood panel can be beneficial. It will help the veterinarian see if the rest of the dog’s body is operating optimally or if there’s an upset that needs to be addressed, hopefully before something serious can happen. An NSAID blood panel should check at least the liver values of ALT, ALP, and AST and the kidney values of BUN and creatine. That said, it doesn’t have to be limited to these and may include a red blood cell count, among other tests.

Alongside an NSAID blood panel, you and your vet should monitor how well the NSAID is controlling your dog’s pain and health in general, including appetite, attitude, and pooping and peeing.

cropped young veterinarian doctors taking blood work from dog
Image Credit: Tyler Olson, Shutterstock

How Often Should an NSAID Blood Panel Be Done?

Monitoring your dog’s response to NSAIDs is a crucial piece of the management puzzle, but the frequency for monitoring isn’t one-size-fits-all. How often you have the blood tests performed will be up to you and your vet. As a general rule, though, every dog should have blood work done before starting NSAIDs, to make sure their body is ready for this medication and to get a baseline of their values.

Since most adverse drug reactions occur within 14–30 days of starting the medication, an NSAID blood panel should be done 2–4 weeks after starting. Of course, if the owner notices any changes in their dog’s appetite or signs like vomiting or diarrhea, repeat blood work can be done sooner.

After that starting phase, the frequency of NSAID blood panels will likely depend on your dog’s age and any other health concerns. For canines over 10 years old, blood tests may be recommended every 3 months. Pups younger than 10 may get by with every 6–12 months. Again, if a dog experiences any adverse effects, speak to your vet rather than wait for your pet’s next scheduled blood panel.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your dog — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

Are Blood Panels Necessary for Dogs on NSAIDs?

Fortunately, severe adverse reactions to NSAIDs are incredibly rare, but it can be catastrophic when they do happen. Therefore, keep a close eye on your dog’s bodily functions at home and the vet’s. NSAID blood panels are the best way to do this, especially if your dog will be taking the medication for the long term. Constant monitoring at home is just as important, though, and should be frequently discussed with your vet.

dog getting a blood test at vet
Image Credit: Elnur, Shutterstock

divider dog paws 3 oct 2024

Conclusion

NSAIDs are frequently used and effective medications for dealing with a dog’s inflammation, but they are far from perfect. They can have side effects that affect the liver, kidneys, and digestive system, especially when taken at high doses or for the long term.

Any canine taking an NSAID for longer than a couple of weeks should receive regular NSAID blood panels before beginning the medication and after 2–4 weeks with it onboard to check organ function. After that, it depends on your pup’s age and your vet’s discretion, but they’re typically done every 3 months for dogs over 10 years and every 6–12 months for pups younger than that.


Featured Image Credit: hedgehog94, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Can You Donate Your Dog’s Body to a Vet Education Program? Vet-Reviewed Facts

Your pet passing may be one of the hardest times in your life, and if you’re looking for a way to make it...

Male vs. Female Dalmatians: The Key Differences (With Pictures)

The Dalmatian is an eye-catching and iconic dog that has been featured in movies and as fire dogs for New York City’s Fire...

5 Best Hunting Dog Collars in 2026 – Reviews & Top Picks

Dogs have been hunting alongside humans for millennia. Labrador retrievers, English setters, beagles, American foxhounds, English springer spaniels, and Chesapeake Bay retrievers all...

Beago (Beagle & Golden Retriever Mix): Info, Pictures, Care & More

The Beago is a cross between two breeds that everyone knows and loves—Beagles and Golden Retrievers. This is a designer breed that’s relatively...

More related

What It’s Really Like to Travel with a Guide Dog

As a world-renowned blind comedian — okay, maybe in my own mind — I am on the road a lot with Nash, my...

What Happens if I Don’t Take My Dog for a Walk? Our Vet Answers

Taking your dog for a walk has its benefits. It gets both you and your dog out for some fresh air and exercise,...

Schapendoes Dog: Breed Info, Pictures, Care & Traits

What isn’t there to love about the Schapendoes? As a little-known herder from the Netherlands, this shaggy-coated breed is an exceptional family dog...

How to Teach a Dog to Wait for Food: 5 Vet-Approved Steps

Dogs would not be dogs if they didn’t show overflowing excitement whenever they caught a whiff of mouthwatering kibble! That said, you may...

Keep reading

10 Best Slow Feeder Dog Bowls in 2026 – Reviews & Top Picks

Some dogs eat their food entirely too quickly, leading to abdominal discomfort to medical emergencies, like bloat (also known as gastric dilatation-volvulus) and choking. To slow down your dog’s eating habits, you may consider trying a slow feeder bowl. These...

dog eating from a slow feeder bowl

How to Start a Dog Food Business: 10 Tips & Tricks

Given how important nutrition is to pet health, starting your own dog food business can be an interesting and even lucrative idea. Indeed, according to IBISWorld, the pet food industry brings in $27 billion a year, and it is growing...

Pet Food Packets At Store

Can Dogs Eat Frosted Mini Wheats? Vet-Reviewed Risks & FAQ

Frosted Mini-Wheats are a popular cereal known for their high fiber and sugary coating. They might be a delicious breakfast for a person, but are they good for dogs? Most importantly, are Frosted Mini Wheats safe for dogs to eat?...

Can Dogs Eat Frosted Mini Wheats

10 Best Legume-Free Dog Foods in 2026 – Reviews & Top Picks

Food sensitivities can make shopping for dog food difficult, especially if your dog is allergic to common ingredients like legumes. While there are benefits to adding legumes to your dog’s diet, there are several reasons that you might prefer to...

dog eating from bowl in kitchen

Evolve Dog Food Review 2026: Recalls, Pros & Cons

Review Summary If you’re looking at different food brands, and trying to decide what would work best with your pooch—let us introduce you to Evolve. It can work very well for the right canine, and we want to explain what...

Dogster_Evolve Dog Food Review

12 Best Moist Dog Foods in 2026 – Reviews & Top Picks

Becoming a dog parent comes with a lot of responsibility, and one of the top priorities is your dog’s diet. Naturally, we want the best for our furry friends and provide them with a well-balanced, nutritious and delicious meal to...

West Highland White Terrier dog at home eating

How Much Does a Cup of Dog Food Weigh? Vet-Approved Guide

Every pet parent wants the best for their pets. This includes feeding your dog the appropriate amount of food each day. While this seems like a simple enough task, it’s trickier than you might think. In fact, a recent study...

measures a portion of dry dog food using an electronic scale

Can Dogs Eat Hash Browns? Vet-Verified Facts, Risks & Diet Tips

Hash browns are a breakfast staple that we often eat alongside eggs, bacon, and sausage. It’s no surprise that your dog may be drooling over the smell of your delicious breakfast, but is it okay to let your pup indulge...

Can Dogs Eat_hash browns