Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

NSAID Panel Blood Test For Dogs: Our Vet Explains Necessity & Frequency

blood samples of a dog for lab testing

Non-steroidal anti-inflammatories (NSAIDs) are used to treat various issues in canines, from short-lived treatment like spay surgery pain to long-term use for osteoarthritis. For most dogs, NSAIDs provide them with pain-free mobility, but using them in the long run can come at a cost. That’s why NSAID panels are so vital.

These blood tests help check the effects that the prescribed NSAID may be having on the dog’s major organs. As a rule, they should be performed before starting treatment and then periodically throughout the process. The frequency will depend on the dog and the situation.

divider single dog paw oct 2024

What Is an NSAID Panel for Dogs?

NSAIDs can work wonders at reducing inflammation and pain from all sorts of ailments. Unfortunately, they may also be negatively affecting certain parts of the body. The digestive system, kidneys, liver, and blood cells are the most common victims.

Keep in mind that side effects are more likely to occur at high doses and when taken with other medications, but they can still happen to an otherwise healthy dog taking only normal levels of NSAIDs.

To monitor these targeted organs, periodically doing an NSAID blood panel can be beneficial. It will help the veterinarian see if the rest of the dog’s body is operating optimally or if there’s an upset that needs to be addressed, hopefully before something serious can happen. An NSAID blood panel should check at least the liver values of ALT, ALP, and AST and the kidney values of BUN and creatine. That said, it doesn’t have to be limited to these and may include a red blood cell count, among other tests.

Alongside an NSAID blood panel, you and your vet should monitor how well the NSAID is controlling your dog’s pain and health in general, including appetite, attitude, and pooping and peeing.

cropped young veterinarian doctors taking blood work from dog
Image Credit: Tyler Olson, Shutterstock

How Often Should an NSAID Blood Panel Be Done?

Monitoring your dog’s response to NSAIDs is a crucial piece of the management puzzle, but the frequency for monitoring isn’t one-size-fits-all. How often you have the blood tests performed will be up to you and your vet. As a general rule, though, every dog should have blood work done before starting NSAIDs, to make sure their body is ready for this medication and to get a baseline of their values.

Since most adverse drug reactions occur within 14–30 days of starting the medication, an NSAID blood panel should be done 2–4 weeks after starting. Of course, if the owner notices any changes in their dog’s appetite or signs like vomiting or diarrhea, repeat blood work can be done sooner.

After that starting phase, the frequency of NSAID blood panels will likely depend on your dog’s age and any other health concerns. For canines over 10 years old, blood tests may be recommended every 3 months. Pups younger than 10 may get by with every 6–12 months. Again, if a dog experiences any adverse effects, speak to your vet rather than wait for your pet’s next scheduled blood panel.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your dog — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

Are Blood Panels Necessary for Dogs on NSAIDs?

Fortunately, severe adverse reactions to NSAIDs are incredibly rare, but it can be catastrophic when they do happen. Therefore, keep a close eye on your dog’s bodily functions at home and the vet’s. NSAID blood panels are the best way to do this, especially if your dog will be taking the medication for the long term. Constant monitoring at home is just as important, though, and should be frequently discussed with your vet.

dog getting a blood test at vet
Image Credit: Elnur, Shutterstock

divider dog paws 3 oct 2024

Conclusion

NSAIDs are frequently used and effective medications for dealing with a dog’s inflammation, but they are far from perfect. They can have side effects that affect the liver, kidneys, and digestive system, especially when taken at high doses or for the long term.

Any canine taking an NSAID for longer than a couple of weeks should receive regular NSAID blood panels before beginning the medication and after 2–4 weeks with it onboard to check organ function. After that, it depends on your pup’s age and your vet’s discretion, but they’re typically done every 3 months for dogs over 10 years and every 6–12 months for pups younger than that.


Featured Image Credit: hedgehog94, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.


How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Can You Use Human OTC Eye Drops on Dogs? Vet-Verified Safety Facts

When dogs experience eye irritation and discomfort, owners will do anything possible to give their dogs some relief. Dog eyes can be highly...

Whipador (Whippet & Lab Mix): Info, Pictures, Care Guide & More

A cross between the Whippet and a Labrador Retriever, few mixes present such a unique appearance and mixture of two completely different breeds....

Lurcher Dog: Breed Info, Pictures, Care & Traits

The Lurcher is a rather niche and obscure breed that is a combination of a Greyhound and another sighthound or scenthound. These dogs...

Why Do Dogs Roll in Stinky Things? Vet-Reviewed Reasons & Prevention Tips

Dogs are notorious for rolling around in just about anything stinky they can find, including dead animals, garbage, and poop. The behavior is...

More related

What Breed of Dog Is Chase From Paw Patrol? Cartoon Dogs Presented

You might be familiar with the cartoon “Paw Patrol” if you have kids.1 If you haven’t seen the show before, it’s a cartoon...

Cane Corso vs. Boxer: Key Differences (With Info & Pictures)

If you’re looking for a larger dog that’s protective of their family, both the Cane Corso and the Boxer are great choices. But...

Nutro Dog Food Review 2026: Pros, Cons & Expert’s Opinion

Review Summary Finding high-quality, tasty, and affordable meals for our dogs is something we’re all searching for in dog food, and Nutro dog...

Shiba Inu Breed Info, Pictures, Traits & Care Guide

Also known as the web-famous “doge,” the compact and fox-faced Shiba Inu is the smallest of the six Japanese native breeds. Renowned mainly...

Keep reading

14 Best Large Breed Puppy Foods in 2026 – Reviews & Top Picks

All humans may be created equal, but not all puppies grow at equal rates or end up the same size when they are done growing. If you have lost your heart to a large or giant breed puppy, there are...

german shepherd puppy eating dry food outdoors

Best Calming Treats for Dogs in 2026 – Reviews & Top Picks

It’s never been a better time to be a dog. The humanization of the pet industry has brought a wealth of new toys, foods, and treats. Research has been done to understand our canine companions better and develop new products...

Owner giving treats as reward for training dog

10 Best Dog Foods for Jack Russells in 2026 – Reviews and Top Picks

Jack Russell Terriers are, without a doubt, a unique breed. The small dog is full of energy, a marvelous digger, and has more love than its little body can hold. While small in size, Jack Russells need a balanced diet...

jack russell terier puppy eating food from bowl

Can You Judge Dog Food Solely by Its First Ingredient? Facts & FAQ

Judging dog food can be overwhelming. There is a lot that you need to keep in mind when checking out dog food. You may be tempted to shorten the process by only looking at the first ingredient. While you can...

Portrait of woman with small dog choosing preserves in pet shop

Can Dogs Eat Gingerbread? Vet-Verified Nutrition Facts & Safety Guide

Gingerbread is a holiday staple many people enjoy for the flavor and nostalgia. While dogs can eat certain holiday foods safely, it’s not recommended for dogs to eat gingerbread or gingerbread cookies. Small amounts of ginger may be okay for...

Can Dogs Eat Gingerbread

10 Best Dog Foods for Pomeranians in 2026 – Reviews & Top Picks

Pomeranians have vastly different nutritional needs than dogs of larger breeds. Small dogs have higher metabolic rates than larger dogs and need to take in a sufficient number of calories to stay healthy. You might be surprised to learn that...

Pomeranian eating dry food from green bowl

Can Dogs Eat Relish? Vet-Reviewed Facts & FAQ

Most dogs are not picky when it comes to what they are eating. They’ll scarf down almost anything that a human companion offers them, and they love rummaging through the garbage for scraps or snatching a piece of food found...

Can Dogs Eat Relish

Can You Add Water to Dry Dog Food? Vet-Approved Benefits & Tips

Many dog owners feed their dogs a combination of wet and dry food, though dry food is definitely more common. Why? Because dry food is cheaper to buy and it’s much easier to prepare. However, dogs of all ages do...

dry dog food with water