Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

NSAID Panel Blood Test For Dogs: Our Vet Explains Necessity & Frequency

blood samples of a dog for lab testing

Non-steroidal anti-inflammatories (NSAIDs) are used to treat various issues in canines, from short-lived treatment like spay surgery pain to long-term use for osteoarthritis. For most dogs, NSAIDs provide them with pain-free mobility, but using them in the long run can come at a cost. That’s why NSAID panels are so vital.

These blood tests help check the effects that the prescribed NSAID may be having on the dog’s major organs. As a rule, they should be performed before starting treatment and then periodically throughout the process. The frequency will depend on the dog and the situation.

divider single dog paw oct 2024

What Is an NSAID Panel for Dogs?

NSAIDs can work wonders at reducing inflammation and pain from all sorts of ailments. Unfortunately, they may also be negatively affecting certain parts of the body. The digestive system, kidneys, liver, and blood cells are the most common victims.

Keep in mind that side effects are more likely to occur at high doses and when taken with other medications, but they can still happen to an otherwise healthy dog taking only normal levels of NSAIDs.

To monitor these targeted organs, periodically doing an NSAID blood panel can be beneficial. It will help the veterinarian see if the rest of the dog’s body is operating optimally or if there’s an upset that needs to be addressed, hopefully before something serious can happen. An NSAID blood panel should check at least the liver values of ALT, ALP, and AST and the kidney values of BUN and creatine. That said, it doesn’t have to be limited to these and may include a red blood cell count, among other tests.

Alongside an NSAID blood panel, you and your vet should monitor how well the NSAID is controlling your dog’s pain and health in general, including appetite, attitude, and pooping and peeing.

cropped young veterinarian doctors taking blood work from dog
Image Credit: Tyler Olson, Shutterstock

How Often Should an NSAID Blood Panel Be Done?

Monitoring your dog’s response to NSAIDs is a crucial piece of the management puzzle, but the frequency for monitoring isn’t one-size-fits-all. How often you have the blood tests performed will be up to you and your vet. As a general rule, though, every dog should have blood work done before starting NSAIDs, to make sure their body is ready for this medication and to get a baseline of their values.

Since most adverse drug reactions occur within 14–30 days of starting the medication, an NSAID blood panel should be done 2–4 weeks after starting. Of course, if the owner notices any changes in their dog’s appetite or signs like vomiting or diarrhea, repeat blood work can be done sooner.

After that starting phase, the frequency of NSAID blood panels will likely depend on your dog’s age and any other health concerns. For canines over 10 years old, blood tests may be recommended every 3 months. Pups younger than 10 may get by with every 6–12 months. Again, if a dog experiences any adverse effects, speak to your vet rather than wait for your pet’s next scheduled blood panel.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your dog — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

Are Blood Panels Necessary for Dogs on NSAIDs?

Fortunately, severe adverse reactions to NSAIDs are incredibly rare, but it can be catastrophic when they do happen. Therefore, keep a close eye on your dog’s bodily functions at home and the vet’s. NSAID blood panels are the best way to do this, especially if your dog will be taking the medication for the long term. Constant monitoring at home is just as important, though, and should be frequently discussed with your vet.

dog getting a blood test at vet
Image Credit: Elnur, Shutterstock

divider dog paws 3 oct 2024

Conclusion

NSAIDs are frequently used and effective medications for dealing with a dog’s inflammation, but they are far from perfect. They can have side effects that affect the liver, kidneys, and digestive system, especially when taken at high doses or for the long term.

Any canine taking an NSAID for longer than a couple of weeks should receive regular NSAID blood panels before beginning the medication and after 2–4 weeks with it onboard to check organ function. After that, it depends on your pup’s age and your vet’s discretion, but they’re typically done every 3 months for dogs over 10 years and every 6–12 months for pups younger than that.


Featured Image Credit: hedgehog94, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

How Fast Can Pitbulls Run? Factors & Uses

Pitbulls are a breed of dog known for their strength, loyalty, and agility. This breed is also capable of running at relatively high...

Can Dogs Eat Fruit Snacks? Vet-Verified Nutrition Info & Risks

If you have kids in the house, there’s a good chance you also have fruit snacks lying around. Fruit snacks are a fan...

Slow Feeder Dog Bowls: Vet-Explained Benefits & Risks

Our dogs love mealtime, no question! But do you suspect your dog might enjoy her food a little too much? Does she wolf...

How to Make Dog Treats to Sell at Home & Start a Business: 11 Tips

If there’s one thing we know about dogs, it’s that they absolutely love having as much food to eat as possible. It seems...

More related

10 Best Canned Dog Foods for Picky Eaters in 2025: Reviews & Top Picks

While it can be a mystery as to why some dogs are picky, finding dog food that a picky dog enjoys can feel...

Chimation (Dalmatian & Chihuahua Mix): Info, Pictures, Care & More

An active little dog with a big personality, the Chimation was developed by intentionally breeding a Dalmatian with a Chihuahua. They combine the...

Whipworms in Dogs: Signs, Causes, and Treatment Options (Vet Answer)

Gastrointestinal parasites commonly infect our four-legged companions. Whipworms are one of the more challenging parasites to rid dogs of due to their long...

Wild Earth Dog Food Review 2025: Our Expert’s Opinion

Wild Earth is a newer brand of vegan dog food on the market. We know what you are thinking—vegan dog food? While we...

Keep reading

Can Dogs Eat Crab Apples? Vet-Verified Nutrition Facts, Benefits & Risks

Have you ever been out on a walk with your pup in the fall season and seen tiny apples littering the ground? Those are crab apples (Malus sylvestris), an older version of European cultivated apple species. These small apples are...

Dogster-Can-Dogs-Eat-Crab Apples

11 Best Foods for Doberman Puppies in 2025: Reviews & Top Picks

If you are about to welcome a sweet Doberman puppy into your life, you need the right gear and supplies to get them off on the right paw. You have purchased a cozy bed, water and food dishes, and handfuls...

doberman puppies sitting

Purina vs. Pedigree Dog Food: 2025 Comparison, Pros & Cons

As a pet parent, you want only the best, healthiest food for your canine friend. However, there are so many choices out there it can get overwhelming pretty quickly. You may have researched several brands and concluded that Purina and...

Dogster_Dog Food Purina VS Pedigree

Can Dogs Eat Agave? Vet-Reviewed Facts & FAQ

Agave nectar (or agave syrup) is a sweeter-than-sugar sweetener derived from the agave plant. Since honey is sometimes recommended for dogs, you might wonder if you can offer Fido a teaspoon or tablespoon of your agave syrup. While agave syrup...

Can Dogs Eat Agave

10 Best Foods for Dogs With Arthritis in 2025 – Reviews & Top Picks

Arthritis and mobility problems in our canine companions are a huge part of the pet industry. One look online and the average person will be overwhelmed with supplements, treats, foods and products all claiming to be “the best” for your...

Beagle Eating Dog Feeding

What Is Choline Chloride in Dog Food? Vet-Approved Facts & Benefits

If you’re one of the people who read the entire ingredients list on your dog’s food before purchasing it, you have likely spotted a few words you weren’t familiar with. One of the things you have likely seen in your...

Dog food in a bowl

Victor vs Taste of the Wild Dog Food: 2025 Comparison, Pros & Cons

Victor and Taste of the Wild are two comprehensive dog food companies that offer a premium variety of excellent recipes. Similar to one another, both lines of food offer grain and grain-free high protein, fiber-rich, fat-dense recipes. These companies set...

Dogster_Dog Food Victor VS Taste of the Wild

10 Best Chicken-Free Dog Foods in 2025: Reviews & Top Picks (Vet-Approved)

Chicken is commonly found in many pet foods. It’s an inexpensive way to add lean protein and healthy nutrients to your dog’s food to keep them at their best. However, sometimes a chicken-free diet is necessary for your pup. If...

dog eating in a food bowl