Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

NSAID Panel Blood Test For Dogs: Our Vet Explains Necessity & Frequency

Share

blood samples of a dog for lab testing

Non-steroidal anti-inflammatories (NSAIDs) are used to treat various issues in canines, from short-lived treatment like spay surgery pain to long-term use for osteoarthritis. For most dogs, NSAIDs provide them with pain-free mobility, but using them in the long run can come at a cost. That’s why NSAID panels are so vital.

These blood tests help check the effects that the prescribed NSAID may be having on the dog’s major organs. As a rule, they should be performed before starting treatment and then periodically throughout the process. The frequency will depend on the dog and the situation.

divider single dog paw oct 2024

What Is an NSAID Panel for Dogs?

NSAIDs can work wonders at reducing inflammation and pain from all sorts of ailments. Unfortunately, they may also be negatively affecting certain parts of the body. The digestive system, kidneys, liver, and blood cells are the most common victims.

Keep in mind that side effects are more likely to occur at high doses and when taken with other medications, but they can still happen to an otherwise healthy dog taking only normal levels of NSAIDs.

To monitor these targeted organs, periodically doing an NSAID blood panel can be beneficial. It will help the veterinarian see if the rest of the dog’s body is operating optimally or if there’s an upset that needs to be addressed, hopefully before something serious can happen. An NSAID blood panel should check at least the liver values of ALT, ALP, and AST and the kidney values of BUN and creatine. That said, it doesn’t have to be limited to these and may include a red blood cell count, among other tests.

Alongside an NSAID blood panel, you and your vet should monitor how well the NSAID is controlling your dog’s pain and health in general, including appetite, attitude, and pooping and peeing.

cropped young veterinarian doctors taking blood work from dog
Image Credit: Tyler Olson, Shutterstock

How Often Should an NSAID Blood Panel Be Done?

Monitoring your dog’s response to NSAIDs is a crucial piece of the management puzzle, but the frequency for monitoring isn’t one-size-fits-all. How often you have the blood tests performed will be up to you and your vet. As a general rule, though, every dog should have blood work done before starting NSAIDs, to make sure their body is ready for this medication and to get a baseline of their values.

Since most adverse drug reactions occur within 14–30 days of starting the medication, an NSAID blood panel should be done 2–4 weeks after starting. Of course, if the owner notices any changes in their dog’s appetite or signs like vomiting or diarrhea, repeat blood work can be done sooner.

After that starting phase, the frequency of NSAID blood panels will likely depend on your dog’s age and any other health concerns. For canines over 10 years old, blood tests may be recommended every 3 months. Pups younger than 10 may get by with every 6–12 months. Again, if a dog experiences any adverse effects, speak to your vet rather than wait for your pet’s next scheduled blood panel.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your dog — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

Are Blood Panels Necessary for Dogs on NSAIDs?

Fortunately, severe adverse reactions to NSAIDs are incredibly rare, but it can be catastrophic when they do happen. Therefore, keep a close eye on your dog’s bodily functions at home and the vet’s. NSAID blood panels are the best way to do this, especially if your dog will be taking the medication for the long term. Constant monitoring at home is just as important, though, and should be frequently discussed with your vet.

dog getting a blood test at vet
Image Credit: Elnur, Shutterstock

divider dog paws 3 oct 2024

Conclusion

NSAIDs are frequently used and effective medications for dealing with a dog’s inflammation, but they are far from perfect. They can have side effects that affect the liver, kidneys, and digestive system, especially when taken at high doses or for the long term.

Any canine taking an NSAID for longer than a couple of weeks should receive regular NSAID blood panels before beginning the medication and after 2–4 weeks with it onboard to check organ function. After that, it depends on your pup’s age and your vet’s discretion, but they’re typically done every 3 months for dogs over 10 years and every 6–12 months for pups younger than that.


Featured Image Credit: hedgehog94, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.




How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

The Crate Setup Most Dog Owners Get Wrong (And How To Fix It!)

Most people assume that if their dog hates the crate, the crate is the problem. So they try a bigger one, a different...

1,500 Beagles Rescued from Wisconsin Lab Farm – Here’s Where They’re Going

You may remember that a few weeks ago, we reported on a tense situation at Ridglan Farms, Wisconsin, a facility infamous for housing...

Dogster’s Weekly Photo Contest Winners: Window Watchers (May 11, 2026)

Every week our team gets the privilege of sorting through our readers photos to choose what dogs will win this weeks contest! See...

Can a Relationship Work When One Person Doesn’t Like Dogs? Tips & When to Walk Away

For dog owners, a partner who doesn’t like dogs isn’t a minor quirk to overlook. Dogs aren’t a hobby you can scale back...

More related

When to Switch to Senior Dog Food? 4 Vet-Reviewed Factors to Consider & Other Tips

Unlike puppy and adult food, senior dog food isn’t technically a type of food. The AAFCO does not list specific nutritional standards for...

Are Dog Shows Ethical? Vet-Verified Facts & FAQ

Many people are against dog shows. However, there are also many breeders and dog owners that are completely for dog shows. The debate...

Black Currant, Evening Primrose & Borage Oils for Dogs (Vet Answer)

Borage oil is a nutritional supplement that is derived from the seeds of the Borage plant. It has become increasingly popular as a...

11 Dog Breeds That Drool the Most: With Info, Pictures & Traits

Dogs are known for their unconditional love and loyalty, but some breeds are also known for their slobbery kisses and puddles of drool...

Keep reading

Nom Nom Dog Food Subscription Review 2026: Our Expert’s Breakdown

* Nom Nom now offers a free Storage Tub with any subscription purchase It used to be that if you wanted to feed your dog fresh, real food, you had to put the work in. You had to get the...

DOG_SAPR_Nom Nom Fresh Dog Food

Can Dogs Eat Pop Rocks? Vet-Verified Facts & FAQ

Pop Rocks certainly are a favorite among consumers for their variety of flavors and all the fun you get to have as they pop, crackle, and fizz in your mouth. Bite down on one and you’re in for even more...

Can Dogs Eat Pop Rocks

How Much Crude Protein Should Be in Dog Food? Vet-Verified Facts & Advice

Finding out how much crude protein should be in dog food, as it turns out, is not an easy question to answer. Let’s explore why. The amount of crude protein that should be in dog food varies. Several variables need...

man buying pet food in the store

Can Dogs Eat Grits? Vet-Verified Nutrition Facts & FAQ

Grits are a popular breakfast staple, especially in southeastern U.S. states. Grits are derived from white corn kernels and are a quick and easy way to grab a little bite to eat before heading out the door in the mornings....

Can Dogs Eat Grits

Can Dogs Eat Alfredo Sauce? Vet Reviewed Nutrition Facts

Alfredo sauce is an Italian sauce made with cheese, butter, cream, and salt, but typically also includes garlic and onion. Dogs do not need to be given extra salt in their diets, and even if your dog can tolerate dairy...

Can Dogs Eat Alfredo Sauce

What Is Fish Meal in Dog Food? Vet-Approved Safety Facts & FAQ

If you’re a dog owner who likes to read pet food labels, you’ll probably find quite a few unfamiliar ingredients listed. One such product is fish meal, commonly found in allergy-friendly diets. But what is fish meal in dog food,...

Wet and dry pet food made of natural ingredients

Can Dogs Have Peppermint? Vet-Verified Safety Facts & FAQ

Peppermint (Mentha piperita) makes an appearance in so many things we eat and drink, particularly around the holidays! But many also use peppermint for its homeopathic uses, of which there are a number of potential benefits to humans. But can...

peppermint plants

Can Dogs Eat Lychee? Vet-Reviewed Nutrition Facts & FAQ

If you like consuming lychees and are a dog parent, you may be wondering if it’s safe for your dog to eat lychee too. So can dogs eat lychee? While dogs should typically stick to regular dog food, giving a...

Can Dogs Eat Lychee

Love Dogs? So Do We! Join the Dogster Community

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.




Sign up for the Dogster Email Newsletter