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6 Best Flea & Tick Sprays for Dogs in 2025 – Reviews & Top Picks

person spraying on dog's paw

person spraying on dog's paw You might not have to worry about fleas and ticks during the cold winter months, but once spring starts to roll around, these tiny insects seem to come out of nowhere. That’s all a part of saying goodbye to winter and hello to warmer months ahead, but the one negative that comes with this seasonal change is that we have to start taking extra preventative measures against fleas, ticks, and other pests.

Controlling these pesky critters isn’t always easy. That’s why finding top reviews of products is so helpful. Nobody wants to deal with an infestation, so we rounded up some of the top sprays that we could find and provided you with each brand’s pros and cons.

divider-pawA Quick Comparison of Our Favorites in 2025

Rating Image Product Details
Best Overall
Winner
Adams Plus Topical Flea & Tick Spray Adams Plus Topical Flea & Tick Spray
  • Affordable
  • Safe on furniture and flooring
  • Works even after it dries
  • Best Value
    Second place
    Vet's Best Indoors Flea & Tick Home Spray Vet's Best Indoors Flea & Tick Home Spray
  • Cheap
  • Natural formula
  • Fresh scent
  • Premium Choice
    Third place
    Wondercide Flea, Tick & Mosquito Spray Wondercide Flea, Tick & Mosquito Spray
  • Clean recipe
  • Fresh smell
  • Safe on dogs and cats
  • Best for Puppies
    Zodiac Flea & Tick Spray Zodiac Flea & Tick Spray
  • Safe for puppies and kittens
  • Quick relief
  • Kills more than fleas and ticks
  • Hartz UltraGuard Plus Flea & Tick Spray for Dogs Hartz UltraGuard Plus Flea & Tick Spray for Dogs
  • Lasts for 7 days
  • Aloe added to soothe skin
  • The 6 Best Flea & Tick Sprays for Dogs

    1. Adams Plus Topical Flea & Tick Spray – Best Overall

    Adams Plus Topical Flea & Tick Spray

    Bottle Size: 16 ounces
    Life Stage: Adult

    Finding the best overall flea and tick spray for dogs comes down to finding something that works without costing you an arm and a leg. This Adams Plus spray gets our vote for the top brand on the market. Spray this solution all over your house without worrying about it destroying your furniture items. You can also spray it directly on carpets or pets to kill fleas and their larvae.

    This is a trusted brand that kills the insects on contact. It even continues to work after the spray dries. Then, all you have to do is continue to reapply every 2 months. While a little does go a long way, there are reports that it does have a strong smell.

    Pros
    • Affordable
    • Safe on furniture and flooring
    • Works even after it dries
    • Lasts for two months
    • Fleas die on contact
    Cons
    • Strong odor

    2. Vet’s Best Indoors Flea & Tick Home Spray – Best Value

    Vet's Best Indoors Flea & Tick Home Spray

    Bottle Size: 32 ounces
    Life Stage: Adult

    The best flea and tick spray for dogs for the money has to be by Vet’s Best. Not only is this pet product affordable, but it is effective in killing insects other than fleas and ticks, like mosquitos. The formula is a plant-based recipe, so you won’t have to worry about any toxins getting in the house. It also smells nice because it uses essential oils as the main ingredients. However, it doesn’t work as quickly as some other products. It might also cause some irritation if your pet has sensitive skin.

    Pros
    • Cheap
    • Natural formula
    • Fresh scent
    • Kills fleas, ticks, and mosquitos
    Cons
    • Doesn’t work quickly
    • Might irritate skin

    3. Wondercide Flea, Tick & Mosquito Spray – Premium Choice

    Wondercide Flea, Tick & Mosquito Spray

    Bottle Size: 4, 16, or 32 ounces
    Life Stage: Adult

    Getting the best pet products on the market usually costs you a little extra money. This Wondercide spray isn’t too expensive, but it might cost you more than some other brands. While it is more costly, the quality is much higher. This spray works on both dogs and cats, so you’re already getting more bang for your buck. It also has a wonderful smell from the natural, clean essential oils used in the formula. There are reports that say it is more effective for fleas than for ticks, though.

    Pros
    • Clean recipe
    • Fresh smell
    • Safe on dogs and cats
    Cons
    • Expensive
    • Better for fleas than ticks

    4. Zodiac Flea & Tick Spray – Best for Puppies

    Zodiac Flea & Tick Spray

    Bottle Size: 16 ounces
    Life Stage: Puppy, kitten, adult

    One thing that the market is lacking is more flea and tick products that are safe for young dogs. The nice thing about this Zodiac flea and tick spray is that it is safe to use on adult dogs and cats, as well as puppies and kittens. It provides quick relief and kills any laid eggs for up to 2 months while still killing adult fleas, lice, ticks, mosquitoes, and gnats.

    Even though it is safe for puppies, it should not be ingested, and you’ll have to be careful not to let your dog’s lick themselves right after you apply it or until it dries. It also has a slight chemical smell that most people aren’t fond of.

    Pros
    • Safe for puppies and kittens
    • Quick relief
    • Kills more than fleas and ticks
    Cons
    • Must watch pets after application
    • Bad odor

    5. Hartz UltraGuard Plus Flea & Tick Spray for Dogs

    Hartz UltraGuard Plus Flea & Tick Spray for Dogs

    Bottle Size: 16 ounces
    Life Stage: Adult

    This spray has a lot to offer in terms of effectiveness. The recipe is formulated to kill any fleas and ticks that come in contact with it for up to 7 days after the application. It also includes aloe so that it is sensitive on your pet’s skin. While it isn’t an all-natural product, it is highly effective. However, some dogs don’t react well to some of the ingredients in it, so you must keep a close eye on them with each use.

    Pros
    • Lasts for 7 days
    • Aloe added to soothe skin
    Cons
    • Not all-natural
    • May cause irritation

    6. Frontline Flea & Ticks Spray for Dogs and Cats

    Frontline Flea & Ticks Spray for Dogs and Cats

    Bottle Size: 8 or 16 ounces
    Life Stage: Adult

    Frontline is a trusted brand that pet owners have used for years. This specific spray is safe to use on both cats and dogs that are older than 8 weeks old. Unfortunately, it does contain chemicals that could be harmful to any sensitive animals. You also might want to use a test area on your furniture to ensure it doesn’t damage it or leave a lingering odor before spraying it on your possessions.

    Pros
    • Safe for dogs and cats over 8 weeks old
    Cons
    • Contains harmful chemicals
    • Bad odor
    • Expensive

    divider-pawBuyer’s Guide: Selecting the Best Flea & Tick Sprays for Dogs

    Putting any sort of chemical-based product on top of your pets is a little risky. Dogs aren’t all the same. Each one has its own sensitivities, and even one simple ingredient could create irritation or health issues if you are not careful. When buying a flea and tick spray, you need to keep your dog’s health a priority over everything else.

    girl spraying on white dog outdoor
    Image By: Vaillery, Shutterstock

    How Does Flea Spray Work?

    There are a couple of different options when it comes to flea and tick spray. While there are sprays, collars, tablets, and shampoos to choose between, they are usually considered either natural or not natural products. Many people today prefer to keep things clean by using sprays that use essential oils to repel fleas and ticks instead of chemicals. On the other hand, chemical-based products do tend to be more effective. The choice is ultimately up to you and what you think the safest option is for your pet and your home.

    What Are the Negatives?

    With all treatments, there are some risks involved with using these products. The most common type of issue to arise is allergic reactions. This usually causes things like hot spots, itchiness, flaking, and other forms of skin irritation. If you notice any of these signs, refrain from using the spray any longer and ask your vet for alternative options.

    If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

    PangoVet_Mention-in-Content Savings V1

    How to Apply Flea and Tick Spray

    You should always test your products to ensure that they are safe for your pet and your home. Apply the spray to a small spot on your dog and your furniture. Check each day after applying the solution to ensure that both your dog’s skin and your furniture aren’t suffering any damage. If they both look okay, you may apply the spray in a larger section and continue to monitor things until you are completely confident that the product is safe and won’t cause any issues.

    How We Selected These Flea & Tick Sprays for Dogs

    This buyer’s guide was carefully crafted by our writers and editors in collaboration with our team of in-house veterinarians. The flea & tick sprays reviewed here are rated on a combination of factors: brand reputation, customer reviews across multiple retail outlets, personal experience, and in some cases, feedback from our own dogs! Together, we choose and review only the best flea & tick sprays available, to help you make the most informed decisions that foster the well-being of your furry friends.

    Why Trust Dogster?

    Dogster has been a trusted brand for dog owners online since 2004, which means we have a lot of experience with flea & tick sprays. We are a team of passionate dog owners who care about our pups as much as you do yours. We want the best for every canine on the planet. Dogster’s writers, editors, and veterinarians are deeply invested in the well-being of our pets, and we believe that all pet owners share this dedication to providing only the highest quality products and services for our dogs.

    divider-pawConclusion

    We hope that these reviews of the top flea and tick dog sprays have helped you come to a decision. The Adams Plus brand may be our vote for best overall, but the Vet’s Pet and Wondercide sprays are both wonderful options that work for different price points.

    Only you can make the final decision between these products. Once you find one that is suitable for your pup, they’ll thank you for protecting them from such pesky insects.


    Featured Image Credit: Nomad, Soul, Shutterstock

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