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11 Best Dog Urine Removers for Stains & Odors in 2025 – Reviews & Top Picks

woman cleaning the carpet with brush and spray

woman cleaning the carpet with brush and spray If you have a dog of any age, you know the importance of having the right tools to clean up urine accidents. Urine doesn’t just leave behind an unmistakable, unpleasant smell, but it also can leave unsightly stains and lead to further accidents in the house if not cleaned up properly. Many dogs will urinate in the same place if they can still smell the previous urine in that spot, so cleaning dog urine up with the right ingredients is the best way to prevent further incidents in your home.

Using our reviews, you can work toward finding the product that works best for your needs. Whether you have a puppy that you’re housetraining or an elderly dog who can’t hold their bladder very long anymore, there’s a urine remover, sometimes referred to as a “dog pee spray”, that will work perfectly for your needs.

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A Quick Look at Our Winners for 2025

Rating Image Product Details
Best Overall
Winner
Hepper Advanced Bio-Enzymatic Pet Stain Eliminator Hepper Advanced Bio-Enzymatic Pet Stain Eliminator
  • Eliminates stains and odors from multiple surfaces
  • Neutral scent with no chemical fragrance
  • 100% satisfaction guarantee
  • Second place
    OUT! Orange Oxy Stain & Odor Remover OUT! Orange Oxy Stain & Odor Remover
  • Can remove stains and odors from multiple surfaces
  • Can be used on old, set-in stains and odors
  • Can be used as a laundry pre-treatment
  • Third place
    Rocco & Roxie Supply Co. Professional Strength Stain & Odor Remover Rocco & Roxie Supply Co. Professional Strength Stain & Odor Remover
  • Two bottle sizes available
  • Uses enzymes to naturally remove odors and stains
  • Can remove stains and odors from multiple surfaces
  • OdoBan Disinfectant OdoBan Disinfectant
  • Great option for homes with puppies
  • Can remove stains and odors from multiple surfaces
  • Highly concentrated
  • Simple Solution Extreme Stain & Odor Remover Simple Solution Extreme Stain & Odor Remover
  • Can remove stains and odors from multiple surfaces
  • Two bottle sizes available
  • Uses pet-safe enzymes and bacteria to clean surfaces
  • The 11 Best Dog Urine Removers

    1. Hepper Advanced Bio Enzymatic Pet Urine Eliminator Spray – Best Overall

    Hepper Advanced Bio-Enzyme Pet Stain and Odor Eliminator Spray

    Size: 32 ounces
    Made to use on: Hard floors, carpets, furniture, fabric
    Primary active ingredient: Active bio-enzymatic blend

    Dealing with dog urine stains is a frustrating part of pet ownership, and finding a product that is powerful enough to combat these accidents the first time can be challenging. For lingering odors or stains, there is one product we cannot recommend enough. The Advanced Bio Enzymatic Pet Stain Eliminator Spray by Hepper is by far the best overall product we have tested. Not only is it effective in removing harsh stains and is a great spray to get rid of the dog urine smells caused by various pet accidents, but it also does it without the use of harsh chemicals, additives, or fragrances.

    Unlike other stain removers, this spray is pet-safe and can be used on a variety of surfaces without damaging the finish or fabric. Made in the USA with eco-friendly components, it was also created to minimize its environmental impact. Additionally, it can be used on all kinds of pet messes, like urine, drool, feces, and vomit. Overall, we think this is the best dog urine remover on the market today.

    The Hepper Spray is 100% guaranteed, so you can contact the company for a full refund if you are dissatisfied with the product.

    At Dogster, we’ve admired Hepper for many years and decided to take a controlling ownership interest so that we could benefit from the outstanding designs of this cool pet company!

    Pros
    • Works for all pet messes
    • Environmentally and pet-safe
    • 100% money-back guarantee
    • Effective in lifting stains and odors
    • Can be used on most surfaces
    Cons
    • Slightly pricier than other sprays

    2. OUT! PetCare Orange Oxy Stain & Odor Remover 

    OUT! PetCare Orange Oxy Stain & Odor Remover

    Size: 32 ounces
    Made to use on: Carpet, laundry, water-safe surfaces
    Primary active ingredient: Hydrogen peroxide

    The best dog urine remover for the money is the OUT! Petcare Orange Oxy Stain & Odor Remover. It removes stains and odors from carpet and water-safe surfaces and can be used as a laundry pre-treatment. OUT! However, urine remover can be used on more than just urine; it is formulated to remove food, feces, vomit, blood, and other stains. It can be used on old, set-in stains and odors.

    Make sure to test it in a small area before using it on stains since hydrogen peroxide is the primary ingredient and can remove the color from some materials. Hydrogen peroxide is an effective and natural cleaning option, and this product has a fresh, light scent that fades quickly after use.

    Pros
    • Best value
    • Can remove stains and odors from multiple surfaces
    • Can be used as a laundry pre-treatment
    • Can be used on old, set-in stains and odors
    • Effective and natural cleaning option
    • Light scent fades quickly
    Cons
    • May remove color from products
    • One size available

    3. Rocco & Roxie Supply Co. Stain & Odor Eliminator

    Rocco & Roxie Supply Co. Professional Strength Pet Stain & Odor Eliminator

    Size: 32 ounces, 1 gallon
    Made to use on: Carpets, furniture, fabric, hard floors
    Primary active ingredient: Enzymatic blend

    The Rocco & Roxie Supply Co. Professional Strength Stain & Odor Remover is a great urine remover option, but it is higher priced than most other products. This pet urine remover spray is available in two sizes and can be used on carpets, hard floors, upholstery, and more.

    It uses enzymes to remove stains and odors naturally and is effective against tough, set-in stains while still being safe for use around pets and children. It has a clean, pleasant smell and can be used to freshen up everything from dog beds to crates, and it is made from eco-friendly products. Some customers mentioned that it is not particularly effective against re-soiling.

    Pros
    • Two sizes are available
    • Can remove stains and odors from multiple surfaces
    • Uses enzymes to remove odors and stains naturally
    • Can be used on old, set-in stains and odors
    • Clean, pleasant smell that can be used to freshen surfaces as well
    • Eco-friendly product
    Cons
    • Premium price
    • May not be effective against re-soiling

    4. OdoBan Disinfectant

    OdoBan Disinfectant Concentrate and Odor Eliminator, 1 Gallon

    Size: 1 gallon
    Made to use on: Laundry, carpet, upholstery, hard surfaces
    Primary active ingredient: Alkyl dimethyl benzyl ammonium chloride

    If you have several stains to clean, the OdoBan Disinfectant is another great option. This disinfectant is highly concentrated, and although it’s only available in one size, a gallon will last a long time. It can be used to clean urine on laundry, floors, crates, dog beds, and more, but it is best to avoid using it on hard floors since it can make them slippery.

    It’s available in two scents: eucalyptus and lavender. The scent fades after a few hours, so it shouldn’t be overpowering. The primary active ingredient is a powerful disinfectant that can be used against various bacteria and fungi.

    Pros
    • A great option for homes with puppies
    • Highly concentrated
    • Can remove stains and odors from multiple surfaces
    • Two scents available
    • Active ingredient is a powerful disinfectant
    Cons
    • One size available
    • May make hard floors slippery

    5. Simple Solution Extreme Stain & Odor Remover

    Simple Solution Extreme Stain & Odor Remover

    Size: 32 ounces, 1 gallon
    Made to use on: Carpets, water-safe surfaces, upholstery, clothing
    Primary active ingredient: Enzymatic blend

    The Simple Solution Extreme Stain & Odor Remover is safe for carpets and most water-safe surfaces. It uses pet-safe bacteria and enzymes to clean urine, vomit, feces, and other unpleasant substances. It is available in two sizes and has a pleasant smell that tends to linger for a while after use, but some customers thought the fragrance smelled too much like a perfume.

    The Simple Solution urine remover’s patented sprayer nozzle can produce a mist, stream, and foam to address stains and odors on different surfaces. However, some users complained that it didn’t prevent their dogs from going in the same spot.

    Pros
    • Can remove stains and odors from multiple surfaces
    • Uses pet-safe enzymes and bacteria to clean surfaces
    • Two sizes available
    • Pleasant smell may linger for a while after use
    • Patented sprayer nozzle emits a mist, stream, or foam
    Cons
    • Fragrance may be too overpowering to some users
    • May not prevent re-soiling

    6. Nature’s Miracle Advanced Stain & Odor Remover

    Nature's Miracle Advanced Dog Enzymatic Stain Remover & Odor Eliminator Spray

    Size: 32 ounces
    Made to use on: Hard floors, carpets, furniture, fabric
    Primary active ingredient: Enzymatic blend

    Nature’s Miracle Advanced Stain & Odor Remover is another great dog urine remover. It’s made to remove stains and odors on everything from dog beds to floors. It uses the power of enzymes to eliminate odors and prevent re-soiling accidents. The fresh scent is pleasant without being overbearing.

    It can also remove odors and stains from feces, blood, vomit, and more. It can even treat old, set-in stains and odors. Several customers found the newer version of this product to have a sprayer that is difficult to use, and this product is only available in one size.

    Pros
    • Removes stains and odors from multiple types of surfaces
    • Active ingredient is enzymes
    • Formulated to prevent re-soiling
    • Fresh scent
    • Can remove stains and odors from multiple surfaces
    • Can be used on old, set-in stains and odors
    Cons
    • Sprayer top may not work properly
    • One size available

    7. TriNova Pet Stain & Odor Remover

    TriNova Pet Stain & Odor Remover

    Size: 32 ounces, 1 gallon
    Made to use on: Carpets, upholstery, fabric
    Primary active ingredient: Enzymatic blend

    The TriNova Pet Stain & Odor Remover is available in two sizes and uses the power of enzymes and bacteria to consume the substance that causes odors and stains. It’s safe to use on carpets, upholstery, dog beds, and other soft surfaces. If the area is wet and the odor-causing bacteria are still damp, TriNova begins working immediately.

    It can be used several times on one spot to treat stubborn, set-in stains and odors. If the area is dried out, multiple applications will likely be necessary. Some users have found that this product may not prevent re-soiling.

    Pros
    • Two sizes available
    • Uses natural enzymes and bacteria for stain and odor control
    • Can remove stains and odors from soft surfaces
    • Begins working immediately on damp stains
    • Can be used several stains to remove tough stains
    Cons
    • Needs multiple applications on dry stains
    • May not prevent re-soiling

    8. Bissell Professional Pet Stain & Odor Remover

    BISSELL Professional Stain & Odor

    Size: 22 ounces
    Made to use on: Carpets
    Primary active ingredient: Enzymatic blend

    The Bissell Professional Pet Stain & Odor Remover is a good option if your stains are exclusive to carpets and rugs. It’s available in one size and can clean organic stains like urine, feces, and food. It has a pleasant scent and begins working immediately on stains and odors. It’s recommended to cover the treated area with a damp towel and allow it to sit for up to 12 hours to thoroughly remove stains and odors, which means you’ll need to keep your dog away from the treated area until the treatment is complete.

    It’s available in a smaller bottle than most other urine removers, so some people find they go through this product quickly. It has a light, fresh scent that dissipates in a few hours.

    Pros
    • Good option for removing stains from carpets and rugs
    • Effective against organic stains
    • Begins working on stains and odors immediately
    • Light, fresh scent
    • Scent dissipates relatively quickly after use
    Cons
    • One size available
    • Works best if allowed to sit for up to 12 hours
    • Smaller bottle than most urine removers

    9. Carbona Oxy Powered Pet Stain & Odor Remover

    Carbona Oxy Powered Dog & Cat Stain & Odor Remover

    Size: 22 ounces
    Made to use on: Carpets, upholstery
    Primary active ingredient: Hydrogen peroxide

    The Carbona Oxy Powered Pet Stain & Odor Remover is available in one size and has a built-in scrub brush, allowing you to get the product deep into your carpets. You can use it as a brush for deeper cleaning and as a sponge for surface stains and odors. It’s formulated for cleaning rugs and carpets.

    Carbona says it can also be used on upholstery, but it states to use the upholstery manufacturer’s recommendations, so it may not be the best pick for upholstered items. It uses hydrogen peroxide and other bleaching agents, but it may remove colors from some products, so always spot-test them before use. It’s formulated to discourage re-soiling.

    Pros
    • Built-in scrub brush
    • Brush has a 2-in-1 design to clean surfaces and deep down in carpet fibers
    • Formulated for cleaning rugs, carpets, and upholstery
    • Effective and natural cleaning option
    • Formulated to discourage re-soiling
    Cons
    • One size available
    • Doesn’t include specific upholstery cleaning instructions
    • May remove color from products

    10. Arm & Hammer Stain & Odor Eliminator for Carpet

    Arm & Hammer Litter Plus Oxiclean Pet Stain & Odor Eliminator

    Size: 32 ounces
    Made to use on: Carpet
    Primary active ingredient: Baking soda

    The Arm & Hammer Stain & Odor Eliminator for Carpet is available in one size and uses natural baking soda to clean carpets and remove odors. It also contains OxiClean to ensure a deep clean and thorough stain removal. It’s designed to prevent re-soiling and is safe for puppies and kittens. It is recommended to only use this product on carpets and rugs, so it’s not a good pick for homes with hard floors or other cleaning needs.

    It is unscented, which may make it a good option for homes with people or animals who are sensitive to smells.

    Pros
    • Effective and natural cleaning option
    • Contains OxiClean to remove set-in stains
    • Designed to prevent re-soiling
    • Unscented
    Cons
    • One size available
    • Recommended only for carpets and rugs

    11. Skout’s Honor Natural Professional Strength Urine Destroyer

    Skout's Honor Professional Strength Urine Destroyer

    Size: 35 ounces, 1 gallon
    Made to use on: Carpets, upholstery, laundry, water-safe surfaces
    Primary active ingredient: Plant-based surfactant

    The Skout’s Honor Natural Professional Strength Urine Destroyer is available in two sizes and can clean carpets and rugs, dog beds, and other laundry, as well as water-safe surfaces like crates and many porous surfaces. It uses the power of plants to clean stains and odors and is safe for pets and children. It’s eco-friendly, biodegradable, and bio-renewable, cruelty-free, and vegan. Some users have reported that this product leaves a residue on some surfaces, and it isn’t the best pick for odor control.

    Pros
    • Two bottle sizes are available
    • Can remove stains and odors from multiple surfaces
    • Uses the power of plants for cleaning
    • Eco-friendly, biodegradable, bio-renewable, cruelty-free, and vegan
    Cons
    • May leave a residue on surfaces
    • Not the best option for odor control

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    Buyer’s Guide: How to Choose the Best Dog Urine Removers

    Choosing the Right Urine Remover for Your Home

    Many urine remover products contain similar ingredients, and choosing the ideal product depends on your preferences for scents or effectiveness. However, there are some notable differences between the urine removers.

    Bleaching Agents vs Bio-Enzymes

    If you are looking for something that will work well on stains but don’t have many concerns about odors or aren’t worried that your dog will re-soil the area, a formula with hydrogen peroxide or another bleaching agent is a good option. It will work on odors but is primarily formulated to treat stains.

    However, if odors are a big concern, enzymatic products and baking soda-based formulas are perfect because the enzymes consume the chemicals causing the odors, and baking soda is well known for its ability to absorb odors and neutralize acidic compounds.

    How We Selected These Best Dog Urine Removers for Stains & Odors

    This buyer’s guide was carefully crafted by our writers and editors in collaboration with our team of in-house veterinarians. The dog urine stain and odor removers reviewed here are rated on a combination of factors: brand reputation, customer reviews across multiple retail outlets, personal experience, and in some cases, feedback from our own dogs! Together, we choose and review only the best dog urine stain and odor removers available, to help you make the most informed decisions that foster the well-being of your furry friends.

    Why Trust Dogster?

    Dogster has been a trusted brand for dog owners online since 2004, which means we have a lot of experience with dog urine stain and odor removers. We are a team of passionate dog owners who care about our pups as much as you do yours. We want the best for every canine on the planet. Dogster’s writers, editors, and veterinarians are deeply invested in the well-being of our pets, and we believe that all pet owners share this dedication to providing only the highest quality products and services for our dogs.

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    Conclusion

    If you’re looking for the perfect urine remover for your home, the best dog urine remover is the Hepper Advanced Bio Enzymatic Pet Stain Eliminator Spray, which is the most effective non-professional product you can get for stains and odors. The most budget-friendly pick is the OUT! Petcare Orange Oxy Stain & Odor Remover, which is affordable for any budget and ideal for treating set-in stains.

    Related Reads:


    Featured Image Credit: VGstockstudio, Shutterstock

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