Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Can Dogs Take Antihistamines? Vet-Verified Safety Facts

blister packs of cetrizine antihistamine tablets

Dogs and humans react to environmental allergies differently. Common symptoms for humans include runny noses and sneezing, but dogs do not tend to suffer from these responses. Instead, they are more likely to have red or itchy skin, hair loss, and red eyes. Because people sometimes take allergy medications, including antihistamines, you may wonder if dogs can do the same. In short, it’s often not the most useful treatment for dogs. Read on to learn more.

divider dog paws 4 oct 2024

What Are Antihistamines?

When the human body detects an allergen or infection, certain cells release histamine. This histamine causes allergy symptoms like a runny nose, sneezing, coughing, and wheezing. Antihistamines inhibit the production of histamines which helps combat or reduce the symptoms associated with allergic reactions. However, once an allergic reaction has started, antihistamines are no longer effective at stopping the inflammation that has been triggered.

antihistamine tablets
Image Credit: Sonis Photography, Shutterstock

Antihistamines for Dogs

Theoretically, dogs may benefit from antihistamines in similar ways to people. However, there are no specific antihistamines that are licensed for dogs, which means that giving the medication is considered off-label usage. Therefore, it must be prescribed by a veterinarian, to ensure it is appropriate for the dog, and to determine dosing. However, often vets will elect other medications that work better for allergies and can suppress the inflammation once it has already started.

Speak to a Vet

As stated previously, before giving antihistamines to your dog, you should speak to your vet. They will advise whether it is the best option, and they will also be able to determine the best dosage for your dog. Inform your vet of any medications, herbal treatments, and supplements your dog is taking and they will be able to advise of any possible drug interactions that might prevent the use of antihistamines, too.

Did you know you can talk to a vet online? Click on the image or button below to schedule a call: PangoVet_Mention-in-Content Savings V1


divider dog paws 4 oct 2024

The 4 Alternative Canine Allergy Treatments

While antihistamines can work in some cases, they won’t work on all dogs for all allergies. There are alternative solutions to help combat the nasty symptoms associated with allergies in dogs.

1. Identify the Source

Try to identify what your dog is allergic to. This can be a specific food or something in the environment. If you suspect environmental allergies, look for plants or anything your dog might come into contact with while in the house, out in the yard, or while out walking.

Some plants cause reactions when your dog brushes up against them and identifying this as the cause of a reaction will help you overcome the problem. Alternatively, you might need to speak to a vet who will be able to help identify the likely cause.

shiba inu dog scratching its ear
Image Credit: MitchyPQ, Shutterstock

2. Elimination

Once you have identified what is causing the allergic reaction, look for ways to eliminate allergens from your dog’s life. If it is a particular perfume, swap it out for another. Similarly, if your dog is allergic to its shampoo, you might need to find an alternative. If it is coming into contact with an allergen while outside, you can try a different route or get rid of the plant in your garden.


3. Symptom Relief

Common allergic skin reactions in dogs are red skin and itchiness. Use a natural shampoo and bathe your dog. Not only will the natural shampoo help relieve itching and potentially enable your dog a little respite from the scratching, but bathing can also get rid of any allergens in the coat and prevent your dog from continuing to come into contact with whatever is causing the itching.


4. Nutritional Therapy

Some foods are labeled as being anti-allergy foods. They might not combat the allergy, but they can help relieve the symptoms and make your dog feel better.

divider dog paws 4 oct 2024

Frequently Asked Questions (FAQ)

How Quickly Do Antihistamines Work?

The speed at which antihistamines work on dogs depends on the actual drug used as well as the severity of the reaction and how much of the drug is administered. Frequently it will take a day or two to see any changes, so ask your vet what to expect.

Do Antihistamines Make Dogs Sleepy?

Antihistamines can potentially make some dogs sleepy, though this depends on the type and the dosage. Dogs generally don’t seem to be as affected as humans, in this regard. If your dog becomes lethargic, you should consult your vet so they can advise on the next steps.

Senior Golden Retriever feeeling sick resting on a dog bed
Image Credit: Yobab, Shutterstock

Dogster_Website dividers_v1_Jan 18 2024-01-TEST

Conclusion

Antihistamines bring relief to human allergy sufferers around the world. They can also, in some cases, be a potential therapy for dogs that are suffering allergic reactions, too, though many other, more effective treatments are often preferred.

If you think your dog may benefit from an antihistamine, speak to your vet to get their recommendation. Some antihistamines are not safe to give to dogs. And a vet will know whether any known drug interactions might cause a bad reaction.

Finally, they will also be able to advise on suitable dosage levels to yield results without causing any potential negative reactions in your dog.


Featured Image Credit: MDV Edwards, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Mission Possible: Meet the Nonprofit Rescuing Puerto Rico’s Stray Dogs

Puerto Rico has an estimated 650,000 stray dogs, affectionately called “satos,” who live on the streets in poor conditions. A combination of low...

Can Dogs Eat Bok Choy? Vet-Verified Health Facts & FAQ

Most dogs love it when you offer them something different from their usual diet, and what could be better than healthy treats like...

Can Dogs Eat Garlic Bread? Vet Approved Facts, Safety Guide & FAQ

Maybe you had some yummy garlic bread for supper and your dog stole a bite, or you’re just wondering if you can feed...

Can a Dog Recover from Parvo? Vet Approved Signs, Treatment & Prevention

A parvo diagnosis in dogs is a serious matter. Parvo is a relatively common disease, but depending on your dog’s age, it could...

More related

What Causes Weight Loss & Diarrhea in Senior Dogs? Vet Explained Health Facts

Nobody likes dealing with diarrhea, especially when it’s plaguing your aging canine companion. But what can be even more concerning is if your...

Do Dogs Have Tickle Spots? Vet-Verified Fun Facts

If you’ve ever given your dog’s belly a good scritch or two, you might have noticed one of their legs kicking out when...

How to Introduce a Cat to a Dog: 8 Vet-Verified Tips

When you adopt a new cat or dog, one of the most challenging parts is introducing them to other members of the family,...

Member’s Mark Dog Food Review 2025: Pros, Cons, Recalls, & FAQ

Review Summary Member’s Mark is the brand of Sam’s Club. Named after its founder, Sam Walton, Sam’s Club is owned by Walmart. The...

Keep reading

10 Best Affordable Puppy Foods in 2025 – Reviews & Top Picks

How can you not fall instantly in love with adorable, roly-poly puppies? But puppies and of course, dogs, end up being expensive to take care of, so it’s always helpful to find ways to save money. Considering that one of...

jack russell terrier dog eating from bowl

10 Best Raw Dog Foods in 2025 – Reviews & Top Picks

Raw food diets come with several benefits for your furry friend. Your dog won’t receive all of the benefits of a raw food diet if you don’t select the best food type available. To make the process at least a...

australian shepherd dog eating, steel bowl

10 Best Rawhide Alternatives for Dogs In 2025 – Reviews & Top Picks 

While some owners swear by rawhide chews, because they are especially good at keeping power chewers busy for hours at a time, many owners refuse to use them. Some manufacturers use chemicals like bleach and hydrogen peroxide to remove the...

A dog and it's antler A brown and white dog lying on it's bed chewing on a deer antler

Can Dogs Have Prunes? Vet-Verified Nutrition Facts & FAQ

Dogs can have a number of fruits and veggies, as they are omnivores just like us! However, our systems are a lot different. So, even though we can safely eat prunes, you may wonder if our pups are able to....

Dogster-Can-Dogs-Have-Prunes

Can Dogs Eat Blackberries? Vet-Approved Facts & FAQ

As man’s best friend and a curious taster, your dog will likely join you foraging for blackberries in the forest, or welcome you home from the grocery store after buying a carton full of berries with equal gusto. They want...

Can Dogs Eat_blackberries

Can Dogs Eat Mochi? Vet-Verified Nutrition Facts & Risks

Dogs don’t stop to think about whether or not they should eat something, so it’s up to us as dog owners to do the thinking for them. If you’ve made mochi and you’re wondering if your dog can have any,...

Can Dogs Eat_mochi

What to Do When Your Dog Won’t Eat: Possible Causes & Solutions (Vet Reviewed)

It can be stressful if your dog suddenly stops eating, especially if they’re typically a big eater. There are a few reasons that some dogs stop eating, and sometimes, it can be difficult to identify the cause, so it’s always...

white dog refuses to eat his food in the bowl

10 Best Raw Dog Food Delivery Services in 2025 – Reviews & Top Picks

It can be overwhelming to choose food for your dog, especially a raw diet. Raw diets have been becoming popular, so many companies are offering raw foods. However, that doesn’t mean all companies produce balanced, high-quality raw diets. We’ve compiled...

raw dog food