Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Maltese Shaker Syndrome: Signs, Causes & Care (Vet Answer)

maltese dog sits on blanket

Most Maltese owners will tell you all about how spunky and in charge their tiny pet with a not so tiny personality is. You can imagine then that waking up to seeing your Maltese (or other little white dog breed) shaking uncontrollably is an alarming development. The good news is this is a rare problem for Maltese dogs, easily treated and we can tell you all about it!

divider dog paws 4 oct 2024

What Is Maltese Shaker Syndrome?

Maltese Shaker Syndrome is a bit of a misnomer, which might explain why it has so many alternative names. Also known as “White Shaker Syndrome,” “Shaker Syndrome,” “Corticosteroid-Responsive Tremor Syndrome,” or “Idiopathic Tremor Syndrome,” these all describe a neurological condition in which typically small, white dogs like Maltese develop repetitive tremors for unknown reasons. Young adult dogs are the most likely to first show signs of this disease and it can happen to any type of dog of any size.

maltese dog
Image Credit: Pixabay

What Causes Maltese Shaker Syndrome?

We’re not actually sure what causes Maltese Shaker Syndrome. It appears to have a genetic component since it runs in certain breeds so strongly, like Maltese and West Highland White Terriers. The disease process is described as a “nonsuppurative meningoencephalomyelitis”.1 That mouthful means there is inflammation of the meninges (membranes lining the central nervous system), brain, and spinal cord and isn’t caused by an infection since no pus is present. Instead, it is thought to be an autoimmune condition, meaning the dog’s immune system starts to attack these tissues and cause inflammation, but we don’t know why.

The only reason we presume this disease is immune mediated is because it responds to immunosuppressives for treatment.

What Are the Signs of Maltese Shaker Syndrome

Dogs with Maltese Shake Syndrome will usually have repetitive, involuntary muscle twitches or tremors that may also look like shivers during voluntary movements. Another sign is intention tremors, which are involuntary muscle movements when anticipating something, like with excitement and exercise. This is because the cerebellum of the brain is affected in this disease and the cerebellum is responsible for fine tuning muscle movements. Due to this the tremors often aren’t present while the dog is sleeping or very relaxed.

In rare cases, some significant signs may be seen such as:
  • Ataxia (unsteady, weaving gait)
  • Nystagmus (eyes that uncontrollably flick back and forth)
  • Head tilt
  • Full body weakness with difficulty standing

If you’re concerned about your pet’s health, you should contact a vet.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's an online service where you can talk to a vet online and get the personalized advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

divider dog paws 4 oct 2024

How Is Maltese Shaker Syndrome Diagnosed?

There is no specific test for Maltese Shaker Syndrome. When a dog is seen by a veterinarian with these signs, they first run tests for everything else it could be. This can include bloodwork, urinalysis, fecal examination, CT scan, MRI, and spinal tap. If everything else has been ruled out and the dog is showing signs of Maltese Shaker Syndrome, then the veterinarian will trial treatment to see if it works, and if it does, this is what provides the diagnosis.

An accurate history and videos of your pet with their signs from home in addition to the physical exam is a great help to your veterinarian in diagnosing Maltese Shaker Syndrome.

How Is Maltese Shaker Syndrome Treated?

As scary as some of this has sounded so far, the great news is that Maltese Shaker Syndrome is easy to treat. Steroids such as prednisone given at an immunosuppressive dose (high) will help calm down the immune system and allow the nervous tissue to heal.

In most cases, dogs will be back to normal in just one to two weeks and will continue to have good control of signs as long as they stay on their steroids, though the dose is brought much lower once signs are controlled. For dogs that cannot take steroids, other immunosuppressive medications can be used.

maltese dog received vaccine
Image By: Lucky Business, Shutterstock

What Is the Prognosis For Maltese Shaker Syndrome?

Maltese Shaker Syndrome has a great prognosis. Nearly all cases will have complete control of signs of the disease within one to two weeks and will likely never have another problem as long as they stay on their steroids throughout their life. In fact, being on steroids over their lifetime is more likely to cause an issue than the Shaker Syndrome itself, though the dose of their steroid will be lowered as much as possible for maintenance to reduce any side effects and chances of complications.

Dogster_Website dividers_v1_Jan 18 2024-03

How Do I Care For a Pet With Maltese Shaker Syndrome?

If you first notice signs of Maltese Shaker Syndrome with your dog, be sure they stay in safe areas, avoiding stairs and ledges they might fall trying to navigate. Be sure to bring them to a veterinarian as soon as you can so they can rule out anything else that might be wrong. If your dog is diagnosed with Maltese Shaker Syndrome, you’ll need to give their medication exactly as prescribed and monitor for changes in their signs.

Hopefully within a week or two your dog will return to normal entirely and then you just need to maintain their daily medication schedule and keep up with their rechecks.

Adorable Young White Teacup Maltese Chilling in the Loving House
Image Credit: Plernz, Shutterstock

Frequently Asked Questions

Is Maltese Shaker Syndrome painful for dogs?

No, thankfully dogs don’t seem to notice that the tremors are even happening and will be otherwise acting just like themselves.

Do dogs grow out of Maltese Shaker Syndrome?

Unlike shaking puppy syndrome, Maltese Shaker Syndrome only resolves with treatment. Luckily treatment is simple, cheap, and easy, as long as you can give your dog a small pill every day.

divider dog paws 4 oct 2024

Conclusion

While not common, Maltese Shaker Syndrome is so characteristic that many people have heard about it anyways. Though startling and upsetting to see at first, a trip to a veterinarian will ease your worries as the disease is very easy to treat and has a great prognosis. Though it seems to have a genetic component, we aren’t sure of ways to prevent it currently so the best thing to do if you have a Maltese or other small white dog breeds that are more prone to the disease is simply monitor for signs such as repetitive tremors, shaking, unsteadiness, and/or shivering.

See also: 


Featured Image Credit: Tanya Dol, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

9 Common Bullmastiff Colors and Patterns (With Pictures)

The large Bullmastiff is a powerful dog breed known for their loyal, loving, and protective nature. Despite their intimidating appearance, a well-trained and...

Do Chihuahuas Shed? Vet-Verified Facts & Info

Chihuahuas are some of the most popular small breeds to exist. Their compact bodies and their hilarious personalities are just a few of...

8 Tips to Find Pet Friendly Housing for You and Your Pup (2025 Guide)

Renting a house or apartment with four-legged roommates can be extremely difficult -- read our tips to help increase your chances....

21 American Dog Breeds: Info, Pictures & Origin

Dogs are bred all around the world, lending to the rich cultures and diversities of each region. When it comes to the U.S.,...

More related

Belgian Malinois Price: 2025 Cost Guide

Choosing a dog to be your companion takes forethought and financial planning. First, you’ll want a dog that fits in with you and...

Why Does My Dog Put Their Paw on Me? 10 Common Reasons

Dogs are amazingly communicative and use their faces and bodies to let us know what they need. Paws are another way our dogs...

How Far Can Dogs Smell? Average & Max Distance

Dogs have a powerful sense of smell that is estimated to be 10,000 to 100,000 times better than that of a human. This...

Top 6 Dog Friendly Beaches Near Tybee Island: Off & On-Leash Places to Go in 2025

About 18 miles from downtown Savannah, Georgia, Tybee Island is often called “Savanah’s Beach.” Tybee Island has long been known as one of...

Keep reading

Can Dogs Eat Pita Chips? Vet-Reviewed Nutrition Facts & FAQ

Made with flour, water, yeast, and salt, pita is a simple snack originally by the Middle East and Mediterranean cultures that easily assimilates into most meals and party foods. Whether you prefer to use it as a mini pizza crust...

Can Dogs Eat Pita Chips

Can Dogs Eat Cottage Cheese? Vet-Verified Nutrition Facts & Safety Guide

Most dogs are far from discerning when it comes to what they put in their mouths. They have no problem getting into the garbage and eating scraps, and they don’t mind devouring whatever they can find on the ground when...

Can Dogs Eat_Cottage Cheese

Can Dogs Eat Lettuce? Vet Approved Facts & FAQs

The good news is that, yes, dogs can eat lettuce. Iceberg lettuce, arugula, and romaine are all varieties of lettuce that your dog can eat. Although lettuce is okay for your dog to eat, it doesn’t provide much nutritional value...

Can Dogs Eat_lettuce

Can Dogs Eat Licorice? Vet-Verified Nutrition Facts & Info

Our pets can eat all sorts of goodies that we can prepare from the comfort of our own kitchens. However, when it comes to sweets, it isn’t always the best idea to share with our four-legged friends. Licorice is not...

twizzlers licorice candies

What Is Dog Food Made Of? Vet-Reviewed Ingredient Guide

Buying dog food is so commonplace. We do it all the time without a second thought. If your dog is running low on food, you hop online or go to the store and grab the same bag you’ve been buying....

german shepherd dog lying near food bowl

Can Dogs Have Sushi? Vet-Verified Facts & FAQ

Your pet is one lucky dog if you’re wondering whether you can give your pet sushi. The sushi market has skyrocketed in recent years, with sales jumping over 23% from 2021 to 2022. People view it as a healthy alternative...

Dogster-Can-Dogs-Have-Sushi

Can Dogs Eat Blackberries? Vet-Approved Facts & FAQ

As man’s best friend and a curious taster, your dog will likely join you foraging for blackberries in the forest, or welcome you home from the grocery store after buying a carton full of berries with equal gusto. They want...

Can Dogs Eat_blackberries

Victor Dog Food vs Purina Pro Plan: 2025 Comparison, Pros & Cons

With so many pet foods on the market, it can be daunting to choose the right one for your dog. Naturally, we want the best for our pups, but the sheer number of brands, ingredients, options, and more can lead...

Dogster_Dog Food Victor VS Purina Pro Plan