Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Maltese Shaker Syndrome: Signs, Causes & Care (Vet Answer)

maltese dog sits on blanket

Most Maltese owners will tell you all about how spunky and in charge their tiny pet with a not so tiny personality is. You can imagine then that waking up to seeing your Maltese (or other little white dog breed) shaking uncontrollably is an alarming development. The good news is this is a rare problem for Maltese dogs, easily treated and we can tell you all about it!

divider dog paws 4 oct 2024

What Is Maltese Shaker Syndrome?

Maltese Shaker Syndrome is a bit of a misnomer, which might explain why it has so many alternative names. Also known as “White Shaker Syndrome,” “Shaker Syndrome,” “Corticosteroid-Responsive Tremor Syndrome,” or “Idiopathic Tremor Syndrome,” these all describe a neurological condition in which typically small, white dogs like Maltese develop repetitive tremors for unknown reasons. Young adult dogs are the most likely to first show signs of this disease and it can happen to any type of dog of any size.

maltese dog
Image Credit: Pixabay

What Causes Maltese Shaker Syndrome?

We’re not actually sure what causes Maltese Shaker Syndrome. It appears to have a genetic component since it runs in certain breeds so strongly, like Maltese and West Highland White Terriers. The disease process is described as a “nonsuppurative meningoencephalomyelitis”.1 That mouthful means there is inflammation of the meninges (membranes lining the central nervous system), brain, and spinal cord and isn’t caused by an infection since no pus is present. Instead, it is thought to be an autoimmune condition, meaning the dog’s immune system starts to attack these tissues and cause inflammation, but we don’t know why.

The only reason we presume this disease is immune mediated is because it responds to immunosuppressives for treatment.

What Are the Signs of Maltese Shaker Syndrome

Dogs with Maltese Shake Syndrome will usually have repetitive, involuntary muscle twitches or tremors that may also look like shivers during voluntary movements. Another sign is intention tremors, which are involuntary muscle movements when anticipating something, like with excitement and exercise. This is because the cerebellum of the brain is affected in this disease and the cerebellum is responsible for fine tuning muscle movements. Due to this the tremors often aren’t present while the dog is sleeping or very relaxed.

In rare cases, some significant signs may be seen such as:
  • Ataxia (unsteady, weaving gait)
  • Nystagmus (eyes that uncontrollably flick back and forth)
  • Head tilt
  • Full body weakness with difficulty standing

If you’re concerned about your pet’s health, you should contact a vet.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

divider dog paws 4 oct 2024

How Is Maltese Shaker Syndrome Diagnosed?

There is no specific test for Maltese Shaker Syndrome. When a dog is seen by a veterinarian with these signs, they first run tests for everything else it could be. This can include bloodwork, urinalysis, fecal examination, CT scan, MRI, and spinal tap. If everything else has been ruled out and the dog is showing signs of Maltese Shaker Syndrome, then the veterinarian will trial treatment to see if it works, and if it does, this is what provides the diagnosis.

An accurate history and videos of your pet with their signs from home in addition to the physical exam is a great help to your veterinarian in diagnosing Maltese Shaker Syndrome.

How Is Maltese Shaker Syndrome Treated?

As scary as some of this has sounded so far, the great news is that Maltese Shaker Syndrome is easy to treat. Steroids such as prednisone given at an immunosuppressive dose (high) will help calm down the immune system and allow the nervous tissue to heal.

In most cases, dogs will be back to normal in just one to two weeks and will continue to have good control of signs as long as they stay on their steroids, though the dose is brought much lower once signs are controlled. For dogs that cannot take steroids, other immunosuppressive medications can be used.

maltese dog received vaccine
Image By: Lucky Business, Shutterstock

What Is the Prognosis For Maltese Shaker Syndrome?

Maltese Shaker Syndrome has a great prognosis. Nearly all cases will have complete control of signs of the disease within one to two weeks and will likely never have another problem as long as they stay on their steroids throughout their life. In fact, being on steroids over their lifetime is more likely to cause an issue than the Shaker Syndrome itself, though the dose of their steroid will be lowered as much as possible for maintenance to reduce any side effects and chances of complications.

Dogster_Website dividers_v1_Jan 18 2024-03

How Do I Care For a Pet With Maltese Shaker Syndrome?

If you first notice signs of Maltese Shaker Syndrome with your dog, be sure they stay in safe areas, avoiding stairs and ledges they might fall trying to navigate. Be sure to bring them to a veterinarian as soon as you can so they can rule out anything else that might be wrong. If your dog is diagnosed with Maltese Shaker Syndrome, you’ll need to give their medication exactly as prescribed and monitor for changes in their signs.

Hopefully within a week or two your dog will return to normal entirely and then you just need to maintain their daily medication schedule and keep up with their rechecks.

Adorable Young White Teacup Maltese Chilling in the Loving House
Image Credit: Plernz, Shutterstock

Frequently Asked Questions

Is Maltese Shaker Syndrome painful for dogs?

No, thankfully dogs don’t seem to notice that the tremors are even happening and will be otherwise acting just like themselves.

Do dogs grow out of Maltese Shaker Syndrome?

Unlike shaking puppy syndrome, Maltese Shaker Syndrome only resolves with treatment. Luckily treatment is simple, cheap, and easy, as long as you can give your dog a small pill every day.

divider dog paws 4 oct 2024

Conclusion

While not common, Maltese Shaker Syndrome is so characteristic that many people have heard about it anyways. Though startling and upsetting to see at first, a trip to a veterinarian will ease your worries as the disease is very easy to treat and has a great prognosis. Though it seems to have a genetic component, we aren’t sure of ways to prevent it currently so the best thing to do if you have a Maltese or other small white dog breeds that are more prone to the disease is simply monitor for signs such as repetitive tremors, shaking, unsteadiness, and/or shivering.

See also: 


Featured Image Credit: Tanya Dol, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.


How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

10 Dog-Friendly Beaches in Maryland to Visit in 2026

Nothing beats a trip to the beach during summer, especially in the company of a trusted dog. And there’s no shortage of fun...

The Art of Nicknaming Your Dog: Tales from the Wednesday Dogs of Dogster (with Video)

Welcome to the Wednesday Dogs of Dogster! Every month, we ask our Dogsters to weigh in on a new topic. This week, we...

Hearing Loss in Dogs: Vet-Reviewed Causes, Signs & What You Can Do

Age-related hearing loss is one of the more common types of hearing loss in dogs. However, dogs can experience it at any life...

Kidney Failure in Dogs: Signs, Care & Treatment Options

The kidneys serve vital functions in your dog’s health. They help to eradicate dangerous toxins that build up in your dog’s body from...

More related

Havapoo (Poodle & Havanese Mix): Info, Pictures, Care & More

The Havapoo is a designer dog bred from Poodle and Havanese parents which can also go by the name of Poovanese. To develop...

Dog Names by Breed: A Complete List From A to Z

When it comes to naming your dog it seems there are some names that are just more common and better suited for a...

Braque d’Auvergne Dog Breed: Info, Pictures, Care & More

If you’re like most people, you’ve probably never heard of the Braque d’Auvergne. That’s a shame because these French gun dogs make wonderful...

$1 Billion in Pet Insurance Claims – Can You Afford Not to Be Insured?

On December 15, 2025, Embrace Pet Insurance, one of the leaders in the pet insurance industry, announced that Juju, a 9-year-old mixed-breed dog...

Keep reading

Should Dogs Eat the Rainbow? Vet-Reviewed Eating Tips for Canines

Dogs are often considered to be carnivores that require a meat-heavy diet. Still, there are some similarities between a dog’s diet and a human’s diet. However, they are not omnivores like we are. Dogs may benefit from eating the rainbow,...

Colorful assorted fruits and vegetables

5 Dog-Friendly Burrito Recipes You Can Make Today (Vet Approved)

Did someone say burrito? Burritos have become a desired cuisine in the U.S., and we’re sure no dog would turn their nose up at the chance for a taste. However, burritos cooked for humans are not particularly friendly for dogs,...

Dog-Friendly Burrito Recipes You Can Make Today

Can Dogs Eat Turkey? Vet-Verified Nutrition Facts & FAQ

If you can’t resist slipping your dog a few tidbits off your dinner plate, you should first know which foods are safe and healthy for them to eat. Turkey is a popular protein, especially for holidays and special occasions, but...

Can Dogs Eat Turkey

Can Dogs Eat Hibiscus? Vet Approved Facts & FAQ

When growing plants in our garden, many dog lovers aren’t aware of the possible toxicity our beautiful plants have which can harm our pets. Hibiscus is a type of perennial flowering plant that adds beauty to many gardens and is...

Can Dogs Eat Hibiscus

How to Tell If Dry Dog Food Has Gone Bad? Signs & 9 Tips to Keep It Fresh

Something you may not think about that often is the expiration date of your dry dog food. And some pet owners may even think that dry dog food stays fresh for way longer than it does. Unlike wet dog food,...

A small dog refuses to eat dog food

Vital Essentials Dog Food Review 2026: An Expert’s Breakdown

More and more dog owners are learning about the benefits of a raw food diet for their furry family members. But feeding a raw diet is even harder than it sounds, especially when you consider what it takes to provide...

Vital Essentials Dog Food

Can Dogs Eat Tahini? Vet-Verified Facts & FAQ

Tahini is delicious, rich, and wholesome! You can find sesame seed paste in many cuisines worldwide, like those in the Middle East, Israel, China, Africa, Japan, Turkey, Iran, and Korea. In addition to providing several vitamins and minerals, tahini is...

Can Dogs Eat Tahini

What Do Rottweilers Eat? Vet-Approved Feeding Guide

Rottweilers are big dogs with big appetites to match, so it’s essential to feed them appropriately to ensure they’re getting the nutrients they need to thrive. However, the number of dog food products available can make choosing the right diet...

rottweiler dog sitting next to an empty bowl