Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

First Vaccines For Puppies: Our Vet’s Guide on Initial Vaccinations

Cute labrador puppy dog getting a vaccine at the veterinary doctor

Bringing a new puppy into your home can be both exciting and overwhelming. You’ll undoubtedly experience the joy that comes with puppy cuddles, playtime, and watching them grow. There’s also a lot to think about—feeding, exercise, toilet training, and vaccinations. But vaccinations don’t need to be stressful.

This article will discuss what to expect, which vaccinations are most important, the possible side effects of vaccinations, and what will happen with vaccinations in the future.

divider dog paws 3 oct 2024

What Happens at Puppy Vaccinations?

Puppy vaccinations are more than just a vaccination. In fact, they are a consultation with a veterinarian. This comprises a full physical exam, checking every part of your puppy from the nose to tail. It is a chance for your vet to assess your puppy’s overall health and check for any hereditary abnormalities.

It is also a chance to discuss training, parasite prevention, and de-sexing. All of these aspects of canine care will be unique to you and your dog – there is no “one size fits all” approach.

The vaccination itself is an injection given under the skin, generally in the scruff of the neck. Depending on the brand and type of vaccination, more than one injection may be necessary. Some forms of “kennel cough” vaccines (see below) are given orally (into the mouth) or intranasally (into the nostril).

Puppy Vaccine
Image Credit: gorillaimages, Shutterstock

Why Do Puppies Need Vaccinations?

Puppies need vaccinations for the same reasons children and people do: to protect against potentially fatal diseases. For the first few weeks of a puppy’s life, they receive antibodies through their mother’s milk. Antibodies are what the immune system sends out to fight foreign substances like viruses and bacteria.

After a few weeks, the levels of these antibodies diminish, as puppies suckle less milk. This puts them at risk of falling ill if they come into contact with infectious diseases. Vaccinations are then given to “train” the dog’s immune system to fight a disease, preparing the body for an effective immune response.

Which Dog Vaccinations Are Necessary?

The first vaccination is generally given between 6 and 8 weeks of age.

Essential Puppy Vaccinations

  • Parvovirus
  • Adenovirus (viral hepatitis)
  • Distemper virus (These vaccines are usually combined into a single injection, sometimes referred to as a “C3” or “DHP” vaccination)
  • Rabies virus (mandatory in the USA)

Strongly Recommended Vaccinations

Optional Vaccinations

  • Leptospira (different “strains” exist)
  • Lyme Disease
  • Rattlesnake toxoid (These vaccinations may or may not be recommended, depending on where you live and your dog’s level of risk. They are given on a “case-by-case” basis)
Cute Labrador puppy getting a vaccine
Image Credit: ARVD73, Shutterstock

Are There Any Side Effects with Dog Vaccinations?

Thankfully, dog vaccinations are very safe and side effects are rare. Side effects sometimes encountered include:

  • Lethargy or reduced appetite
  • Vomiting
  • Swelling of the face and neck
  • Hives
  • Swellings or tenderness at the injection site

We recommend contacting a veterinarian if you notice any of these signs at home.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your dog — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

divider dog paws 3 oct 2024

How Long Before My Dog Is Protected?

Generally, puppies are considered immune 7 days after their second vaccination. Until they have had their final puppy vaccination, it’s best to avoid high-density doggy areas such as dog parks and beaches.

When Is the Next Round of Vaccinations Due?

The second round of vaccinations is given one month after the first. Your vet will discuss with you when the final vaccine is due; this is usually at or just after 16 weeks of age.

black dachshund getting a vaccine
Image Credit: Masarik, Shutterstock

divider dog paws 3 oct 2024

Conclusion

Vaccines are a safe, easy, and affordable way to reduce the risk and incidence of preventable canine diseases. Don’t underestimate the importance of puppy vaccinations. At the same time, don’t let puppy vaccinations stress you out. Remember, your vet will guide you through which vaccinations are best and when vaccinations will be due.


Featured Image Credit: ARVD73, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

At What Age Do Puppies Lose Their Teeth? Vet-Verified Facts & FAQ

Like humans, dogs have baby teeth that fall out as their adult teeth come in. If you are a first-time canine owner, you...

Honest Paws CBD Pet Products Review 2025: An Expert’s Breakdown

Review Summary If you’ve ever owned a cat or dog, you know how much they love to play. But both dogs and cats...

How Much Does It Cost to Make Your Dog an Emotional Support Dog? 2025 Guide (Vet-Reviewed)

Though they exist in a class separate from service animals, emotional support animals (ESAs) can be a life-changing benefit for individuals with social...

How to Reduce Dog Shedding: 9 Vet-Approved Tips & Tricks

You adore your dog, but not so much all the shedding they do. Having dog hair everywhere (on the sofa! On your clothes!...

More related

Why Is My Dog Leaking Urine Suddenly? Causes & Vet-Approved Treatments

As a dog owner, you’ve learned to expect the unexpected. From emergency vet visits to coming home to find your couch destroyed—you’ve probably...

Tumble Rug Review 2025: An Expert’s Breakdown

If you have a furry friend, chances are, you’ve cleaned up a mess or two in your time as a pet parent. Maybe...

12 Fun Winter Activities to Do With Your Dog (2025 Guide)

Whether you’re the type of person who loves to see snow on the ground in the winter or one who prefers to stay...

Adopt a Ryan Reynolds? Rescue Shelter Renames Pets to Boost Adoptions on Actor’s Birthday

On October 23rd, Ryan Reynolds’ 48th birthday, his friend and business partner (co-chairman of the Wrexham AFC team) Rob McElhenney came up with...

Keep reading

Finn Dog Supplements Review 2025: An Expert’s Breakdown

Have you ever found yourself searching high and low for the perfect supplements to meet your dog’s needs? It can be confusing with the number of products on the market, and many of them are designed in fancy and eye-catching...

DOG_SAPR_Finn Dog Supplements

7 Best Low-Fat Dog Foods in 2025 – Reviews & Top Picks

Getting an overweight dog to shed some pounds can be challenging, but it’s the best thing for them. Obesity can lead to other health issues, like high blood pressure, heart disease, and diabetes. As much as we love our pups...

Ginger dog eating

What Is Ash in Dog Food? Vet Approved Facts & FAQ

If you’ve been checking out the nutritional label on your dog’s bag of food and your first thought was something along the lines of “What the…?!” when you spotted “ash” listed—you can stop worrying now. Dog food manufacturers are not...

Black Dachshund dog guarding and eating food

How to Get a Puppy to Eat Dry Food: 10 Tips & Tricks

Owning a puppy can be one of the most hilarious, adorable, heartwarming, and frustrating experiences that anyone can have. Taking care of a puppy has various challenges, and ensuring that they get the right nutrition is one of them. When...

Cocker Spaniel puppy eating

Can Dogs Eat Zucchinis? Vet-Verified Info, Benefits & Risks

Our hungry canine friends are always tempted to eat food items that they shouldn’t, especially when they see you eating something. While certain fruits and vegetables, like onions, should be avoided, plenty of alternatives are completely safe for your dog....

Can Dogs Eat_zucchinis

Nom Nom vs Spot & Tango: Which Fresh Dog Food is Better? 2025 Update

If you’re tired of researching dog food brands, don’t worry, you’re not alone. In the last 20 years, several new dog food manufacturers have entered the market to compete in the premium product category. Although the number of producers can...

Dogster_Dog Food Nom Nom VS Spot & Tango

10 Frozen Dog Treat Recipes: Great Summer Options for Your Pup

Dogs love treats in all shapes and forms, and there are so many commercial options to choose from. But when it’s a hot summer day, a frozen treat tends to hit the spot much better than a commercial or homemade...

Frozen Dog Treat Recipes

Are Tomato Plants Toxic to Dogs? Vet-Verified Facts & Safety

If you get online regarding feeding dogs tomatoes, you’ll get mixed opinions. Some say that you should never give your dog any tomatoes, despite their ripeness, while others claim that ripe tomatoes can be okay in moderation. Ultimately, you should...

Dogster_Are Tomato Plants Toxic to Dogs