Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

8 Common Puppy Illnesses & Diseases to Be Aware Of

cheerful young veterinary taking care and examining a beautiful pet dog french bulldog.

Puppies have so much growing up to do! Part of that process involves developing a healthy and strong immune system. As puppies age, they start to lose the protective antibodies that they acquired from their mother and begin to develop their own immune defenses.

However, this transition can make them vulnerable to sickness, especially those that aren’t fully vaccinated. The following list highlights the common illnesses and diseases that puppies can acquire.

divider dog paws 4 oct 2024

The 8 Common Puppy Illnesses & Diseases to Be Aware Of

1. Parvovirus (Parvo)

Parvovirus attacks the gastrointestinal system and causes signs like vomiting, bloody diarrhea, lethargy, anorexia, and dehydration. The virus is transmitted through contaminated feces, is highly contagious, and can prove fatal. The virus is also hardy in the environment and may survive for months or years. Ideally, puppies diagnosed with parvo should be hospitalized, as there is no cure for the disease, only supportive care.

mixed breed puppy with parvovirosis at the veterinary clinic
Image Credit: Todorean-Gabriel, Shutterstock

2. Distemper

Like parvo, distemper is a highly contagious and often fatal virus. It can attack the nervous, gastrointestinal, and respiratory systems, producing signs like seizures, head tilt, circling, fever, lethargy, coughing, and discharge from the eyes and nose. Some puppies develop thickened paw pads and may have dental abnormalities if they survive the disease. Other puppies may have neurological abnormalities that persist for life. Distemper virus can be transmitted in respiratory droplets from sneezing or coughing or from contaminated food and water bowls. There’s no cure but there is supportive care.


3. Canine Infectious Respiratory Disease (Kennel Cough)

Canine infectious respiratory disease is a common and easily transmissible respiratory virus among dogs. It may be caused by bacteria (like Bordetella bronchiseptica), a virus (like canine parainfluenza virus or canine coronavirus), or both. Most infections resolve on their own in 1–3 weeks, while more severe signs may require treatment like antibiotics, an anti-inflammatory, and a cough suppressant from your veterinarian. Severe cases of kennel cough may lead to pneumonia.

If your puppy is diagnosed with kennel cough, use a body harness instead of a collar so the pressure does not irritate their trachea.

Brindle Cane Corso standing on a grass field outdoors while wearing a harness
Image Credit: Eudyptula, Shutterstock

4. Leptospirosis

Leptospirosis is an infection caused by bacteria (Leptospira) that are shed through infected urine. It can be transmitted in contaminated water sources that are visited by wildlife and livestock, soil, bedding, or any surface containing infected urine. The infection attacks the kidneys and liver and is typically treated with antibiotics and aggressive fluid therapy in more severe cases.

Despite treatment, the disease can be fatal. It is also contagious to humans, making it a zoonotic disease. Care must be taken around puppies and dogs diagnosed with leptospirosis to avoid catching it. This includes wearing disposable gloves and washing your hands after cleaning up after your dog.


5. Adenovirus

Adenovirus is a virus that causes infectious canine hepatitis in puppies and dogs. It usually attacks the liver and is spread through contact with an infected animal or surface. Signs may include lethargy, inappetence, fever, vomiting, and diarrhea. There’s no cure, only supportive care. Unfortunately, the survival rate is low, only 1–30%.

sick weakened puppy lies in the arms of owner
Image Credit: Gladskikh Tatiana, Shutterstock

6. Rabies

Rabies is always fatal once clinical signs develop. This deadly virus is shed in saliva and transmitted through the bite of an infected animal. The signs may include behavioral changes, neurological abnormalities, hyperexcitability, or paralysis. Rabies is also contagious for humans, so if you’ve been bitten or scratched by a strange dog, you must seek medical care immediately.


7. Parasites

Internal and external parasites can affect puppies. Common internal parasites include roundworms, hookworms, stomach worms, tapeworms, giardia, coccidia, and heartworms. External parasites include fleas, ticks, mites, and lice.

owner applying flea and tick medicine to a dog
Image Credit: Nick Alias, Shutterstock

8. Vomiting and Diarrhea

Vomiting and diarrhea in a puppy can be caused by several underlying conditions that a veterinarian should evaluate. Common conditions include foreign bodies, toxins, stress, sudden diet changes, or bacterial, viral, or parasitic-related illnesses.

Dogster_Website dividers_v1_Jan 18 2024-03

How Can I Keep My Puppy Safe?

Start with the core vaccinations, such as DA2PPv, when your puppy reaches 6–8 weeks old.

This combination vaccine includes:
  • Distemper virus
  • Adenovirus type 2
    • This cross-protects against Adenovirus type 1, which causes infectious canine hepatitis; type 2 causes tracheobronchitis.
  • Parainfluenza (tracheobronchitis)
  • Parvovirus

To provide the best protection, it’s administered every 2–4 weeks until your puppy is 16–20 weeks old.

Another vaccine to consider is the one for canine infectious respiratory disease, especially the one caused by the bacterium Bordetella bronchiseptica. Puppies can get this starting at 8 weeks of age, especially if they’re exposed to other dogs. It’s also known as kennel cough or infectious tracheobronchitis and is common in dogs in kennels or boarding situations.

The leptospirosis vaccine can be started at 12 weeks of age. At this time, puppies can also be dewormed and started on flea-and-tick prevention to prevent infestations. Depending on the age of your puppy and your state laws, puppies can receive a rabies vaccine starting at 12–16 weeks of age. This would be best discussed with your veterinarian.

Ideally, your puppy should be fully vaccinated before interacting with other dogs at around 16 weeks of age. However, socialization in puppies is also crucial. If there are puppy socialization classes near you, you may be able to sign up for one that has puppies of similar ages and vaccine status. If you would like to bring your puppy out in public, you can do so by holding and carrying them around, to lessen the chance of disease transmission from other dogs.

If you’re unsure about your puppy’s health, growth, or vaccine schedule, its recommended that you contact your vet.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

Dogster_Website dividers_v1_Jan 18 2024-03

Conclusion

Puppies have an underdeveloped immune system, which can make them more susceptible to certain diseases. Taking precautions like vaccinating and supervising interactions with other dogs and places is crucial. Avoid places where the unknown vaccination status of dogs is frequent, such as dog parks, until your puppy is fully vaccinated.

Sources

Featured Image Credit: Hryshchyshen Serhii, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.


How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Japanese Terrier Dog Breed: Info, Pictures, Facts & Traits

The Japanese Terrier is a little-known dog that is a fascinating blend of East and West. Much like modern Japan itself, this breed...

Are Poodles Good With Kids? Vet-Approved Family Dog Guide

When you’re considering adding a new puppy to the family, it can be impossible to know which breed will seamlessly complement your lifestyle,...

20 Tallest Dog Breeds: Info, Pictures, History & More

“Bigger is better” is a popular motto; for some people, that motto extends to the canines in their lives. Some dogs are incredibly...

Jelly vs the Brush: A 13-Year Battle

Hi, I’m Allison. Read my introduction to learn more about me and my three mixed-breed dogs from Thailand, Jelly, Lorraina, and Manic. If...

More related

Am I Ready for a Dog? 7 Questions to Ask Yourself First

So you wonder if you’re ready to have a dog. First, we have to commend you for taking the commitment so seriously that...

Great Dane vs German Shepherd: Notable Differences (With Pictures)

Beginning the search for the ideal breed of dog to join your life can be an exciting process, but one that requires a...

Do German Shepherds Make Good Pets? Facts & Tips

The German Shepherd is a handsome, fiercely loyal, and intelligent dog that can be the perfect pet for some families. However, whether the...

Introducing the Dogsters: Savanna and Penny, Her Spunky Chihuahua Mix

Hi, I’m Savanna Stanfield, a former science teacher and now a writer and editor at Dogster. I’ll be sharing my life with Penny,...

Keep reading

Can Dogs Eat Pita Chips? Vet-Reviewed Nutrition Facts & FAQ

Made with flour, water, yeast, and salt, pita is a simple snack originally by the Middle East and Mediterranean cultures that easily assimilates into most meals and party foods. Whether you prefer to use it as a mini pizza crust...

Can Dogs Eat Pita Chips

PetPlate Dog Food & Supplement Subscription Review 2026: Door Delivery For Your Pup Made Fresh

Are you considering switching your dog to a dog food delivery service but struggling to find one that includes enough variety to suit your dog’s needs? If that’s the case, PetPlate might be the best choice for you. This subscription...

DOG_SAPR_PetPlate Human-Grade Dog Food

Can Dogs Eat Pork? Vet-Approved Nutrition Facts & FAQ

There is always a time for pork, whether it’s crispy bacon to accompany your waffles, pork sausages for lunch, or a pork roast with all the trimmings for a special occasion. There are many opportunities where pork can get your...

Can Dogs Eat Pork

9 Best Dog Foods for Pyoderma in 2026 – Reviews & Top Picks

Pyoderma is a serious skin condition in dogs. Often, it involves small pustules developing on the surface of the dog’s skin. However, there are many different symptoms, including hair loss, itching, and dry skin. Different breeds are more prone to...

shiba inu dog scratching its ear

Can Dogs Eat Limes? Vet-Approved Facts & FAQ

Disclaimer: Before changing your dog’s/ cat’s diet or introducing new ingredients or supplements that they haven’t eaten before, especially when it comes to human food, make sure to consult your veterinarian first. Every dog/cat is different and requires an individual...

Can Dogs Eat Limes

Can Dogs Eat Custard? Vet Approved Advice

Pastries and sweets are delicacies that us humans enjoy regularly. As curious creatures, dogs will often show interest in our food. It is no secret that dogs will beg you for a taste of whatever delicious snack you’re eating! As...

Can Dogs Eat_Custard

Why Does My Dog Walk Away From Their Food? 3 Vet-Reviewed Reasons & What to Do

If you’re noticing that your dog likes to check out their food but doesn’t actually do much eating, it can be extremely frustrating. Or perhaps you’re finding that your dog is taking their food out of their bowl to eat...

dog not eating its food

11 Best Dog Foods for Huskies in 2026 – Reviews & Top Picks

If you own a Siberian Husky, then you’re well aware of their high energy levels. But did you know that Huskies also have extremely high metabolisms? This does have something to do with their high energy levels, but it has...

Husky-puppy-eating-from-feeding-bowl-indoors