Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

4 DIY Homemade Enzyme Cleaner Recipes for Dog Urine: Easy & Effective

Share

White vinegar in spray bottle and baking soda in glass jar

When disaster strikes in the form of dog pee somewhere it should not be, what you need is an enzyme cleaner to tackle the smell and stain. Store-bought enzyme cleaners are great, especially in terms of convenience, but they can be pricey.

An alternative is to make your enzyme cleaner with what you’ve got available at home. In this post, we’ll share some simple but effective homemade enzyme cleaner recipes you can make today.

dogster paw divider

The Importance of Effective Cleaning

Since dogs’ noses are a bit more in tune than humans, they can detect scents, good or bad, long after we’ve cleaned them and can no longer smell them ourselves. Homemade cleaners are awesome in an emergency, but with these gentle solutions, many stains and odors can begin to reappear after some time. If the goal is to eradicate these for good, investing in a tough enzyme cleaner is your best bet and luckily, there are many pet-friendly products on the market.

If you're looking for an all-in-one, pet-friendly, enzyme cleaner, we highly recommend the Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray.

Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray
  • ADVANCED ENZYMATIC CLEANER - Penetrates the most stubborn smells and stains at the deepest molecular...
  • FOR ANY MESS, ON ANY SURFACE - This pet odor eliminator cleans your carpets, floors, furniture,...
  • FRESH, NATURAL ODOR - Our unique formulation doesn't rely on dangerous or unpleasant chemical...

It eliminates tough stains and odors easily and is excellent for accident prevention. Plus, it comes with a 100% satisfaction guarantee! Click here to order now.

At Dogster, we’ve admired Hepper for many years, and decided to take a controlling ownership interest so that we could benefit from the outstanding products of this cool pet company!

divider dog paws 2 oct 2024

The 4 DIY Homemade Enzyme Cleaner Recipes for Dog Urine

1. White Vinegar & Water Solution by wikiHow

What You’ll Need: Water, white vinegar, spray bottle
Difficulty Level: Easy

If you are looking for something almost entirely hassle-free, look no further than this very basic homemade enzyme cleaner made of two simple ingredients—white vinegar and water. Acidic vinegar is very effective at cutting through dirt, grease, buildup, and watermarks on objects around your home, but it’s also good at eliminating odors and getting rid of stains.

To make this cleaner, all you need to do is mix equal parts water and vinegar in a spray bottle. Just take note that if you’re targeting hardwood floors, the finish might be damaged by white vinegar, so proceed with caution. If you’re worried but want to use vinegar, you can try making a weaker solution with more water. It’s also a good idea to spot-test an inconspicuous area first to check for its effects.


2. White Vinegar & Water with Essential Oils Solution by The Spruce

DIY vinegar spray for all-purpose cleaning
Image Credit: the spruce
What You’ll Need: Water, distilled white vinegar, essential oils, spray bottle, measuring cup, funnel
Difficulty Level: Easy

To add an extra hint of freshness, you can DIY a white vinegar and water solution with some drops of essential oil, like lavender, rosemary, or a combination of oils. This recipe is made just like the standard white vinegar and water solution, but you just need to add 12–24 drops of essential oil into the mix.

The only issue with a recipe like this is that some essential oils, including ylang-ylang, peppermint, tea tree, and citrus can be toxic to pets if they lick it or get it on their skin. For this reason, if you go with this recipe, be sure to keep pets away from the cleaning area.


3. White Vinegar & Baking Soda Solution by Home Made Simple

DIY white vinegar and baking soda solution
Image Credit: Home Made Simple
What You’ll Need: Baking soda, white vinegar, warm water, vacuum cleaner, damp towel
Difficulty Level: Easy

If you’re targeting tough pee stains, one idea is to combine the power of white vinegar and baking soda, another simple household item that’s great at working out both stains and odors. This method is especially good for tackling pet pee stains on carpets and rugs.

All you need to do is soak up excess liquid with paper towels, spray white vinegar with water on the affected area, and sprinkle baking soda on top. Cover, leave it to dry, and then vacuum the baking soda.


4. Hydrogen Peroxide & Dishwashing Detergent Solution by CJs Chem-Dry

hydrogen peroxide with cleaning products
Image Credit: Danijela Maksimovic, Shutterstock
What You’ll Need: Liquid dish soap (detergent), 3% hydrogen peroxide, warm water, vacuum, spray bottle
Difficulty Level: Easy

If you’re dealing with seriously stubborn stains and smells, 3% hydrogen peroxide is another common and effective household disinfectant. As detailed in this recipe, you can try combining four tablespoons of 3% hydrogen peroxide with two tablespoons of warm water and a few drops of dish soap in a spray bottle to make this cleaner.

A few things to bear in mind with this recipe:
  • Hydrogen peroxide should be 3% or lower
  • Do a spot test first if possible
  • Keep pets away from the area while it’s drying

dogster paw divider

How to Stop Dogs from Peeing in the House

If your dog is peeing inside, unless they suffer from issues like stress, separation anxiety, or a urinary tract infection, it’s likely because they simply haven’t learned yet where it is and isn’t appropriate to pee. This behavior is common in puppies learning the ropes and adopted dogs that weren’t properly socialized at a young age.

Though it can be frustrating, it’s important to remain calm and avoid punishing your dog for these accidents, as this can make things worse—stressed dogs are more likely to pee inside out of fear and submission.

Instead, take your dog outside at regular intervals. This should encourage them to sniff around and urinate, and be sure to praise and reward them when they do, perhaps with a tasty treat. If an accident occurs indoors, simply take the dog outside as quickly as possible to their favorite “pee spot.” You’ll likely need to do this several times before your dog gets the hang of things.

woman training dog indoors
Image By: LightField Studios, Shutterstock

Potential Medical Conditions

Peeing Inside Due to Anxiety

On the other hand, if your dog is peeing as a result of anxiety, it’s time to assess possible triggers in their environment and work on those. Do they pee when you leave the house? This could be separation anxiety. Or perhaps they urinate when they hear loud sounds like bangs—this is a sign that they’ve experienced some form of trauma before they came to you.

In these kinds of situations, you’ll want to look into how you can minimize your dog’s anxiety, for example, by desensitizing them gradually to the sounds they’re afraid of or creating positive associations with spending time alone. If you’re finding this challenging, consider reaching out to a professional behaviorist for advice.

Urinary Tract Infections

Sometimes, urinary tract infections can cause a dog with usually good bathroom habits to start peeing indoors. Signs include frequent urination, drinking more, foul-smelling urine, licking the private parts after peeing, and a lack of bladder control. If your dog is displaying any of these signs or otherwise appears to be in pain, please contact your vet to get them treated.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

divider single dog paw oct 2024

Summing Up

With a few basic and inexpensive ingredients you can find around your home, you’ll be able to whip up a DIY homemade enzyme cleaner in no time. If this is more than just a one-off accident, it’s a good time to address why your dog might be peeing indoors. Please see your vet if you suspect that a urinary tract infection or another condition is behind it.


Featured Photo Credit: Foto Helin, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.




How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

The Hidden Risk in Tall Grass That Most Dog Owners Ignore

Finding a tick on your dog can look like a lot of things, depending on when you catch it. Some are engorged and...

America’s Most Popular Dog Breed Is Also One of the Unhealthiest

We’re now 3 for 3 in the category of disappointing canine accolades with the French Bulldog being announced as America’s most popular dog...

Ask Dr. Paola- Help! My Dog Keeps Barking at the TV! (March 30, 2026)

Welcome to our “Ask Dr. Paola” series, where every Monday we bring expert advice straight from Dr. Paola Cuevas (MVZ) to help our...

Dogster’s Weekly Photo Contest Winners: I’m a Messy Eater (March 26, 2026)

Every week our team gets the privilege of sorting through our readers photos to choose what dogs will win this weeks contest! See...

More related

Can Dogs Eat Soy? Vet-Reviewed Nutrition Facts & Info

Soy has gotten a bad reputation for being a cheap filler without any nutritional value. However, this isn’t always true. Soy can be...

250+ Viking Dog Names: Strong Names for Your Warrior Pooch

When you get a puppy or dog, naming them is one of the things people look forward to the most. There are so...

Do Dogs Have Nightmares? Vet-Verified Canine Facts

If you’ve ever seen your dog’s legs kick as they sleep, you’ve likely assumed that your four-legged friend has dreams like you do....

How Much Are French Bulldogs in 2026? Pricing Guide

Do you have your eye on a French Bulldog? They are popular dogs, but how much will they cost? In this blog post,...

Keep reading

5 Best Bully Sticks for Puppies in 2026 – Reviews & Top Picks

Most dogs love to chew, especially as puppies. During the teething process, puppies seek out hard objects to chew to relieve the likely discomfort of the teething process1. Puppies will also chew if they’re bored. In either case, if your...

beagle puppy chewing bully stick

Is Flaxseed Good for Dogs? Vet-Verified Benefits, Risks & Tips

Feeding your dog a well-balanced diet that is suitable for their unique needs is important for their overall health and well-being. So, as dog owners, we want to incorporate the healthiest, most nutritious foods in our pet’s diets, so they...

brown flaxseeds

Can Dogs Eat Tamales? Vet-Verified Nutrition Facts & FAQ

Tamales are popular in Mexican cuisine, and people worldwide love to eat them. If you also love to eat tamales and have a dog, you’ve probably noticed your canine lurking around, looking for tamale scraps. Tamales are not suitable for...

Can Dogs Eat Tamales

Can Dogs Eat Ants? Vet-Verified Facts & FAQ

As curious animals, dogs are bound to eat ants at some point in their life. Those little insects that you need to protect your sugary foods from can be found everywhere. Your dog is likely going to eat ants from...

Can Dogs Eat_Ants

8 Best Wet Dog Foods in the UK in 2026 – Reviews & Top Picks

We want to give our dogs the best life, and part of that means providing nutritious food. If you are searching for the best wet food to give your pup or are thinking about switching from dry food to wet,...

shih tzu dog getting wet food from owner at kitchen

How to Tell If Wet Dog Food Has Gone Bad? 7 Vet-Verified Signs & FAQ

Commercial dog food comes in many forms, including wet food. The phrase “wet food” refers to food that is usually in one of two forms: canned or fresh. They often have real pieces of meat in them and a strong...

shih tzu dog getting wet food from owner at kitchen

10 Best Vet-Recommended Puppy Foods in 2026 – Reviews & Top Picks

We spend a lot of time thinking about feeding ourselves and our families, and it’s easy—find a recipe, order takeout, or sign up for home delivery, and mostly, eat what tastes good! But how do you pick an all-important food...

Cocker Spaniel puppy eating

Can Dogs Eat Frosted Mini Wheats? Vet-Reviewed Risks & FAQ

Frosted Mini-Wheats are a popular cereal known for their high fiber and sugary coating. They might be a delicious breakfast for a person, but are they good for dogs? Most importantly, are Frosted Mini Wheats safe for dogs to eat?...

Can Dogs Eat Frosted Mini Wheats

Love Dogs? So Do We! Join the Dogster Community

Stay informed with expert pet care insights delivered straight to your inbox! Discover professional guidance on animal behavior, feeding tips, trusted product picks, and much more.




Sign up for the Dogster Email Newsletter