Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

8 Common Puppy Illnesses & Diseases to Be Aware Of

cheerful young veterinary taking care and examining a beautiful pet dog french bulldog.

Puppies have so much growing up to do! Part of that process involves developing a healthy and strong immune system. As puppies age, they start to lose the protective antibodies that they acquired from their mother and begin to develop their own immune defenses.

However, this transition can make them vulnerable to sickness, especially those that aren’t fully vaccinated. The following list highlights the common illnesses and diseases that puppies can acquire.

divider dog paws 4 oct 2024

The 8 Common Puppy Illnesses & Diseases to Be Aware Of

1. Parvovirus (Parvo)

Parvovirus attacks the gastrointestinal system and causes signs like vomiting, bloody diarrhea, lethargy, anorexia, and dehydration. The virus is transmitted through contaminated feces, is highly contagious, and can prove fatal. The virus is also hardy in the environment and may survive for months or years. Ideally, puppies diagnosed with parvo should be hospitalized, as there is no cure for the disease, only supportive care.

mixed breed puppy with parvovirosis at the veterinary clinic
Image Credit: Todorean-Gabriel, Shutterstock

2. Distemper

Like parvo, distemper is a highly contagious and often fatal virus. It can attack the nervous, gastrointestinal, and respiratory systems, producing signs like seizures, head tilt, circling, fever, lethargy, coughing, and discharge from the eyes and nose. Some puppies develop thickened paw pads and may have dental abnormalities if they survive the disease. Other puppies may have neurological abnormalities that persist for life. Distemper virus can be transmitted in respiratory droplets from sneezing or coughing or from contaminated food and water bowls. There’s no cure but there is supportive care.


3. Canine Infectious Respiratory Disease (Kennel Cough)

Canine infectious respiratory disease is a common and easily transmissible respiratory virus among dogs. It may be caused by bacteria (like Bordetella bronchiseptica), a virus (like canine parainfluenza virus or canine coronavirus), or both. Most infections resolve on their own in 1–3 weeks, while more severe signs may require treatment like antibiotics, an anti-inflammatory, and a cough suppressant from your veterinarian. Severe cases of kennel cough may lead to pneumonia.

If your puppy is diagnosed with kennel cough, use a body harness instead of a collar so the pressure does not irritate their trachea.

Brindle Cane Corso standing on a grass field outdoors while wearing a harness
Image Credit: Eudyptula, Shutterstock

4. Leptospirosis

Leptospirosis is an infection caused by bacteria (Leptospira) that are shed through infected urine. It can be transmitted in contaminated water sources that are visited by wildlife and livestock, soil, bedding, or any surface containing infected urine. The infection attacks the kidneys and liver and is typically treated with antibiotics and aggressive fluid therapy in more severe cases.

Despite treatment, the disease can be fatal. It is also contagious to humans, making it a zoonotic disease. Care must be taken around puppies and dogs diagnosed with leptospirosis to avoid catching it. This includes wearing disposable gloves and washing your hands after cleaning up after your dog.


5. Adenovirus

Adenovirus is a virus that causes infectious canine hepatitis in puppies and dogs. It usually attacks the liver and is spread through contact with an infected animal or surface. Signs may include lethargy, inappetence, fever, vomiting, and diarrhea. There’s no cure, only supportive care. Unfortunately, the survival rate is low, only 1–30%.

sick weakened puppy lies in the arms of owner
Image Credit: Gladskikh Tatiana, Shutterstock

6. Rabies

Rabies is always fatal once clinical signs develop. This deadly virus is shed in saliva and transmitted through the bite of an infected animal. The signs may include behavioral changes, neurological abnormalities, hyperexcitability, or paralysis. Rabies is also contagious for humans, so if you’ve been bitten or scratched by a strange dog, you must seek medical care immediately.


7. Parasites

Internal and external parasites can affect puppies. Common internal parasites include roundworms, hookworms, stomach worms, tapeworms, giardia, coccidia, and heartworms. External parasites include fleas, ticks, mites, and lice.

owner applying flea and tick medicine to a dog
Image Credit: Nick Alias, Shutterstock

8. Vomiting and Diarrhea

Vomiting and diarrhea in a puppy can be caused by several underlying conditions that a veterinarian should evaluate. Common conditions include foreign bodies, toxins, stress, sudden diet changes, or bacterial, viral, or parasitic-related illnesses.

Dogster_Website dividers_v1_Jan 18 2024-03

How Can I Keep My Puppy Safe?

Start with the core vaccinations, such as DA2PPv, when your puppy reaches 6–8 weeks old.

This combination vaccine includes:
  • Distemper virus
  • Adenovirus type 2
    • This cross-protects against Adenovirus type 1, which causes infectious canine hepatitis; type 2 causes tracheobronchitis.
  • Parainfluenza (tracheobronchitis)
  • Parvovirus

To provide the best protection, it’s administered every 2–4 weeks until your puppy is 16–20 weeks old.

Another vaccine to consider is the one for canine infectious respiratory disease, especially the one caused by the bacterium Bordetella bronchiseptica. Puppies can get this starting at 8 weeks of age, especially if they’re exposed to other dogs. It’s also known as kennel cough or infectious tracheobronchitis and is common in dogs in kennels or boarding situations.

The leptospirosis vaccine can be started at 12 weeks of age. At this time, puppies can also be dewormed and started on flea-and-tick prevention to prevent infestations. Depending on the age of your puppy and your state laws, puppies can receive a rabies vaccine starting at 12–16 weeks of age. This would be best discussed with your veterinarian.

Ideally, your puppy should be fully vaccinated before interacting with other dogs at around 16 weeks of age. However, socialization in puppies is also crucial. If there are puppy socialization classes near you, you may be able to sign up for one that has puppies of similar ages and vaccine status. If you would like to bring your puppy out in public, you can do so by holding and carrying them around, to lessen the chance of disease transmission from other dogs.

If you’re unsure about your puppy’s health, growth, or vaccine schedule, its recommended that you contact your vet.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

Dogster_Website dividers_v1_Jan 18 2024-03

Conclusion

Puppies have an underdeveloped immune system, which can make them more susceptible to certain diseases. Taking precautions like vaccinating and supervising interactions with other dogs and places is crucial. Avoid places where the unknown vaccination status of dogs is frequent, such as dog parks, until your puppy is fully vaccinated.

Sources

Featured Image Credit: Hryshchyshen Serhii, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.

How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.

Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

How Many Dogs are There in the UK? 2025 Statistics & Facts

Note: This article’s statistics come from third-party sources and do not represent the opinions of this website. In the United Kingdom, there are...

10 Best Dog-Friendly Vacation Destinations in the US (2025 Guide)

A vacation should be a relaxing prospect, but when you throw a dog in the mix, planning can stress you out. Boarding your...

Nom Nom vs. Ollie Dog Food: Our 2025 In-Depth Comparison

With the recalls and controversies surrounding commercial dog kibble, many concerned dog owners started searching for alternative dog food as a response. Over...

Neakasa P1 Pro 5-in-1 Pet Grooming Kit Review 2025: Cleaning Up the Grooming Process

If you’ve ever taken your dog to the groomer, you know how expensive it can be, especially for longhaired breeds. You may have...

More related

Are Rottweilers Good With Cats? Facts & FAQ

Despite the longstanding rivalry between dogs and cats, there are plenty of dogs that get along just fine with cats and vice versa....

Can Bird Mites Live on Dogs? Vet-Verified Facts & FAQ

Bird mites are parasites found in wild birds and poultry. They are generally brown or grayish in color and turn darker after feeding....

My Dog Swallowed a Corn Cob: Our Vet Explains Signs, Next Steps & Prevention Tips

You had company over for a barbecue, and your furriest family member stole an ear of corn on the cob from someone’s plate....

Warlock Doberman: Info, Pictures, History & Origin

The Warlock Doberman, also known as the King Doberman, is a bigger, more muscular crossbreed between a Doberman and either a Great Dane...

Keep reading

What Are By-Products in Dog Food? Vet-Reviewed Facts & Info

I spend more time and consideration making sure the pet food I choose is good quality than I do my food. I check protein, fiber, and other nutrient ratios while trying to decipher the ingredients. As with processed human food,...

Dalmatian dog eating dry food from a bowl

What Exotic Fruits Can Dogs Eat? 10 Vet-Verified Safe Options

Unlike cats who are obligate carnivores, dogs are omnivores. In addition to animal-based proteins, they can eat a range of vegetables and fruits, and we don’t just mean your everyday bananas and blueberries, either. Like us, dogs can indulge in...

plateful of mangoes

Can Dogs Eat Cornmeal? Vet-Verified Facts

Cornmeal is often used in commercial dog food, so it is reasonable to assume that it’s safe for your dog to eat. And this is true; cornmeal isn’t toxic to dogs, it provides nutrients and energy, and it is something...

Can Dogs Eat Cornmeal

Can Dogs Eat Plums? Vet-Verified Nutrition Facts & Risks

While choosing and preparing fruits and vegetables for your canine friend, it’s essential to be mindful of specific options that may not suit them. For example, you might be curious whether plums are safe for dogs. While dogs can eat...

Can Dogs Eat Plums

Purina vs. Pedigree Dog Food: 2025 Comparison, Pros & Cons

As a pet parent, you want only the best, healthiest food for your canine friend. However, there are so many choices out there it can get overwhelming pretty quickly. You may have researched several brands and concluded that Purina and...

Dogster_Dog Food Purina VS Pedigree

Is Dry Dog Food Bad for Dogs? Vet-Reviewed Pros & Cons

There has been controversy surrounding dry food in the dog food world for years now. Proponents of raw food and fresh food diets argue that dry dog food is unhealthy due to being highly processed, but others have a more...

pouring dog food

Can Dogs Have Green Tea? Vet-Verified Facts & FAQ

We all want the best for our pets. After all, we consider them family members. Therefore, it’s understandable why you might want to give your pup some calming green tea. Some scientific evidence suggests green tea may have human health...

Dogster-Can-Dogs-Have-Green-Tea

TBHQ in Dog Food: Vet-Approved Feeding & Safety Facts

TBHQ, or tertiary butylhydroquinone, is likely an ingredient that you aren’t familiar with. This chemical additive is commonly used in pet foods to extend shelf life and keep the food from going rancid. You might be surprised to know that...

person pouring dog food to a bowl