March 2nd 2013 6:42 am
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This is a timeline forensics of why knowlege if family lines, and testing is critical. deep family history knowlege all contributed in saving a life.
A genetic condition that could have been passed along was stopped because of routine ultrasound screenings on apparently healthy dogs.
Here is a timeline to demonstrate an actual dog (MINE) of how health testing works, the importance, how open communication health networking of other breeders and owners makes a critical difference.
Dec 28 2005 Tuck Born
2010- Completed health Testing
2005 SEARCH and RESCUE Certified, TD, CD, TDX titles
2008 Champion (Also winning 5 breed specialties)
CHIC OFA-Elbows OFA-Cardiac OFA-HIPS OFA-THYROID OFA-PAtellas OFA-Kidneys OFA-PRA CERF
2010 Becomes father
2011 Tuck's mother died of splenic cancer at age 7, then siblings follow suit
Tucks father died of Spleenic cancer at age 14 1/2 (Tuck was frozen semen and father died in 2004)
2012 Tuck's puppy diagnosed with renal agenesis by ultrasound and dye studies
Discovery discloses this is a hereditary incomplete dominant gene. Further study with familial history points out the patterns associated with the renal agenesis gene has been there the entire time unrecognized, starting with Tuck's mother, imported from Norway, who had problems carrying litters to term, with absorbed puppies, mummy puppies, detached placentas, undeveloped puppies, and puppies that died within 1 day of birth,
Malnouriashed uterine horns,
When Tuck was bred, the bitch had a previous history of normal litters. When bred to Tuck, the history of dying puppies at or shortly after birth continued.(2010) Necropsies were not done. In retrospect, upon discovery of the renal agenesis in Bob, and looking back on the familial history, everything came together in 2012. The only thing missing was the necropsy on thse dead puppies, which would have confirmed bilateral renal agenesis.
Several generations were born of puppies dying at birth. There had been no earlier familial history of this until Tuck was born, and it's suspected this gene was imported with Tuck's mother. Making Tuck a carrier. When he became a father again, the puppies dying at birth, PLUS BOB's discovery that he had renal agenesis pinpointed Tuck as the Renal agenesis carrier. Almost assuredly through his mother (Already dead by the time of discovery) Tuck has two normal kidneys and cleanly passes the OFA kidney test) -- So does Bob, who has one kidney. OFA Screening does not catch this condition
Dec 2012 A routine screening shows a small node
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