Get

In Your Inbox

Dogster is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

8 Common Puppy Illnesses & Diseases to Be Aware Of

cheerful young veterinary taking care and examining a beautiful pet dog french bulldog.

Puppies have so much growing up to do! Part of that process involves developing a healthy and strong immune system. As puppies age, they start to lose the protective antibodies that they acquired from their mother and begin to develop their own immune defenses.

However, this transition can make them vulnerable to sickness, especially those that aren’t fully vaccinated. The following list highlights the common illnesses and diseases that puppies can acquire.

divider dog paws 4 oct 2024

The 8 Common Puppy Illnesses & Diseases to Be Aware Of

1. Parvovirus (Parvo)

Parvovirus attacks the gastrointestinal system and causes signs like vomiting, bloody diarrhea, lethargy, anorexia, and dehydration. The virus is transmitted through contaminated feces, is highly contagious, and can prove fatal. The virus is also hardy in the environment and may survive for months or years. Ideally, puppies diagnosed with parvo should be hospitalized, as there is no cure for the disease, only supportive care.

mixed breed puppy with parvovirosis at the veterinary clinic
Image Credit: Todorean-Gabriel, Shutterstock

2. Distemper

Like parvo, distemper is a highly contagious and often fatal virus. It can attack the nervous, gastrointestinal, and respiratory systems, producing signs like seizures, head tilt, circling, fever, lethargy, coughing, and discharge from the eyes and nose. Some puppies develop thickened paw pads and may have dental abnormalities if they survive the disease. Other puppies may have neurological abnormalities that persist for life. Distemper virus can be transmitted in respiratory droplets from sneezing or coughing or from contaminated food and water bowls. There’s no cure but there is supportive care.


3. Canine Infectious Respiratory Disease (Kennel Cough)

Canine infectious respiratory disease is a common and easily transmissible respiratory virus among dogs. It may be caused by bacteria (like Bordetella bronchiseptica), a virus (like canine parainfluenza virus or canine coronavirus), or both. Most infections resolve on their own in 1–3 weeks, while more severe signs may require treatment like antibiotics, an anti-inflammatory, and a cough suppressant from your veterinarian. Severe cases of kennel cough may lead to pneumonia.

If your puppy is diagnosed with kennel cough, use a body harness instead of a collar so the pressure does not irritate their trachea.

Brindle Cane Corso standing on a grass field outdoors while wearing a harness
Image Credit: Eudyptula, Shutterstock

4. Leptospirosis

Leptospirosis is an infection caused by bacteria (Leptospira) that are shed through infected urine. It can be transmitted in contaminated water sources that are visited by wildlife and livestock, soil, bedding, or any surface containing infected urine. The infection attacks the kidneys and liver and is typically treated with antibiotics and aggressive fluid therapy in more severe cases.

Despite treatment, the disease can be fatal. It is also contagious to humans, making it a zoonotic disease. Care must be taken around puppies and dogs diagnosed with leptospirosis to avoid catching it. This includes wearing disposable gloves and washing your hands after cleaning up after your dog.


5. Adenovirus

Adenovirus is a virus that causes infectious canine hepatitis in puppies and dogs. It usually attacks the liver and is spread through contact with an infected animal or surface. Signs may include lethargy, inappetence, fever, vomiting, and diarrhea. There’s no cure, only supportive care. Unfortunately, the survival rate is low, only 1–30%.

sick weakened puppy lies in the arms of owner
Image Credit: Gladskikh Tatiana, Shutterstock

6. Rabies

Rabies is always fatal once clinical signs develop. This deadly virus is shed in saliva and transmitted through the bite of an infected animal. The signs may include behavioral changes, neurological abnormalities, hyperexcitability, or paralysis. Rabies is also contagious for humans, so if you’ve been bitten or scratched by a strange dog, you must seek medical care immediately.


7. Parasites

Internal and external parasites can affect puppies. Common internal parasites include roundworms, hookworms, stomach worms, tapeworms, giardia, coccidia, and heartworms. External parasites include fleas, ticks, mites, and lice.

owner applying flea and tick medicine to a dog
Image Credit: Nick Alias, Shutterstock

8. Vomiting and Diarrhea

Vomiting and diarrhea in a puppy can be caused by several underlying conditions that a veterinarian should evaluate. Common conditions include foreign bodies, toxins, stress, sudden diet changes, or bacterial, viral, or parasitic-related illnesses.

Dogster_Website dividers_v1_Jan 18 2024-03

How Can I Keep My Puppy Safe?

Start with the core vaccinations, such as DA2PPv, when your puppy reaches 6–8 weeks old.

This combination vaccine includes:
  • Distemper virus
  • Adenovirus type 2
    • This cross-protects against Adenovirus type 1, which causes infectious canine hepatitis; type 2 causes tracheobronchitis.
  • Parainfluenza (tracheobronchitis)
  • Parvovirus

To provide the best protection, it’s administered every 2–4 weeks until your puppy is 16–20 weeks old.

Another vaccine to consider is the one for canine infectious respiratory disease, especially the one caused by the bacterium Bordetella bronchiseptica. Puppies can get this starting at 8 weeks of age, especially if they’re exposed to other dogs. It’s also known as kennel cough or infectious tracheobronchitis and is common in dogs in kennels or boarding situations.

The leptospirosis vaccine can be started at 12 weeks of age. At this time, puppies can also be dewormed and started on flea-and-tick prevention to prevent infestations. Depending on the age of your puppy and your state laws, puppies can receive a rabies vaccine starting at 12–16 weeks of age. This would be best discussed with your veterinarian.

Ideally, your puppy should be fully vaccinated before interacting with other dogs at around 16 weeks of age. However, socialization in puppies is also crucial. If there are puppy socialization classes near you, you may be able to sign up for one that has puppies of similar ages and vaccine status. If you would like to bring your puppy out in public, you can do so by holding and carrying them around, to lessen the chance of disease transmission from other dogs.

If you’re unsure about your puppy’s health, growth, or vaccine schedule, its recommended that you contact your vet.

If you need to speak with a vet but can't get to one, head over to PangoVet. It's our online service where you can talk to a vet online and get the advice you need for your pet — all at an affordable price!

PangoVet_Mention-in-Content Savings V1

Dogster_Website dividers_v1_Jan 18 2024-03

Conclusion

Puppies have an underdeveloped immune system, which can make them more susceptible to certain diseases. Taking precautions like vaccinating and supervising interactions with other dogs and places is crucial. Avoid places where the unknown vaccination status of dogs is frequent, such as dog parks, until your puppy is fully vaccinated.

Sources

Featured Image Credit: Hryshchyshen Serhii, Shutterstock

Want content like this delivered to you?

Sign Up For Our Newsletter

News, insights, expert advice, and everything dog

* By submitting, you agree to our Terms & Conditions and Privacy & Cookies Policy.


How useful was this post?

Click on a star to rate (you can leave written feedback after clicking submit)

Help us improve Dogster for pet parents!

Your feedback really matters.

What did you like about this post? Also how can we improve it?

Join the conversation

Leave a Reply

You’re very welcome to leave a comment or question. Please know that all comments must meet our community guidelines, and your email address will NOT be published. Let’s have a positive and constructive conversation.


Talk With A Vet Online

Peace of mind,
anywhere, anytime

Affordable vet advice

Saint Shepherd (Saint Bernard German Shepherd Mix): Info, Pictures, Care & More

The Saint Shepherd is a relatively new and uncommon hybrid dog breed. They’re known to have the intelligence of a German Shepherd and...

19 Dog Breeds Similar to Labradors (With Info & Pictures)

Labradors are the most beloved dogs in America (and have been since 1991), and for good reason; the breed is sociable, loyal, fun,...

Why Do Dogs Like Tug of War? Vet-Approved Benefits, Tips & Considerations

Every dog is different. Some like to charge from room to room; others like to chase a tennis ball. If you’re lucky, they...

Saint Pyrenees (Saint Bernard & Great Pyrenees Mix): Info, Pictures & Care

The Saint Pyrenees is a mixed breed with Saint Bernard and Great Pyrenees parentage. With ancestors like that, it’s no wonder that Saint...

More related

Kangal Dog Breed: Info, Pictures, Facts, & Traits

The Kangal is a dog with a strong and powerful presence. Bred to guard livestock from predators, these dogs are loyal to their...

Best Canned Pumpkin for Dogs: Our Top 6 Picks in 2026

Pumpkin isn’t just an autumn treat anymore—especially when it comes to your dog. Canned pumpkin is a popular treat and dog food topper,...

When Will My Corgi’s Ears Stand Up? Vet-Reviewed Facts & FAQ

Pembroke Welsh Corgis are at 11th place, and Cardigan Welsh Corgis are at 63rd place among the most popular dogs in the United...

Male vs Female Chihuahuas: What’s The Difference (With Pictures)

Chihuahuas are among the most popular dog breeds on the planet, and it’s not hard to see why: They become deeply attached to...

Keep reading

10 Best Dog Foods to Avoid DCM in 2026 – Reviews & Top Picks

DCM stands for dilated cardiomyopathy. If a dog is diagnosed with DCM, their heart muscle is enlarged and weakened, potentially causing valves to leak. Over time, this leads to congestive heart failure. In 2018, the FDA announced that it was...

brown dog eating its food

Can Dogs Eat Cornbread? Vet-Approved Facts & FAQ

During dinner, your dog may stand near you and beg for table scraps, but some food is unhealthy and hazardous to canines. Cornbread seems harmless enough, and it is generally safe to serve. Dogs can enjoy a little cornbread occasionally,...

Can Dogs Eat Cornbread

6 Food High in Magnesium for Dogs: Vet-Reviewed Facts & FAQ

Like humans, dogs require essential minerals and vitamins to function. Magnesium, along with calcium, phosphorus, and potassium, is an essential macromineral. It’s important for bone formation, muscle, and nerve function. Magnesium must be included in the diet in sufficient amounts...

dog eating in a food bowl

Can Dogs Eat Waffles? Vet-Verified Nutrition Facts & Risks

It’s nice to spend time with your pet in the morning and share a good breakfast with them, which has many people wondering if it is safe to feed waffles to dogs. It might be fine for your dog to...

Can Dogs Eat_waffles

Senior Dog Food vs Regular: The Differences, Pros & Cons

As dog owners know, the food that we feed our pups is essential to keeping them healthy. When our dogs start getting older, their bodies change, and so do their nutritional needs. After your dog reached a certain age (which...

Dogster_Senior vs Regular Dog Food

Can Dogs Eat Bay Leaves? Vet Approved Facts & FAQ

Dogs often have a way of charming their way to eating their humans’ table food. While many of us find them irresistible and often give in, feeding them scraps of our own food, it’s important to know if the food...

Can Dogs Eat_bay leaves

14 Best Large Breed Puppy Foods in 2026 – Reviews & Top Picks

All humans may be created equal, but not all puppies grow at equal rates or end up the same size when they are done growing. If you have lost your heart to a large or giant breed puppy, there are...

german shepherd puppy eating dry food outdoors

Can Dogs Eat Pork? Vet-Approved Nutrition Facts & FAQ

There is always a time for pork, whether it’s crispy bacon to accompany your waffles, pork sausages for lunch, or a pork roast with all the trimmings for a special occasion. There are many opportunities where pork can get your...

Can Dogs Eat Pork