An older dog lying down on the floor, maybe sick.

Is Benadryl Safe for Dogs? What to Know About Benadryl for Dogs

Regular-strength Benadryl is a common OTC antihistamine. So, is Benadryl safe for dogs? Let’s look at how and when Benadryl might be recommended for dogs with allergies, anxiety, insect stings or bites, and motion sickness.