all of a sudden having accidents and afraid?

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i wiggle my- entire body
Barked: Sun Jun 9, '13 8:51pm PST 
Lexi is all of a sudden having accidents in her kennel when i am gone(4 hrs) She never did this before and nothing has changed. I have taken her to the vet and she got a clean bill of health. Shes not drinking any more than usual. Also she is now afraid of riding in the car she will pant and kind of freak herself out. not sure where that came from either as she was always ok with it. nothing has changed at all. could this be a fear stage? how can i help her?