Malamute diagnosed with Eosinophilic Granuloma. Lesion in mouth does not respond to treatment. Any recommendations?

Our 68 lb Alaskan Malamute, Ice, was diagnosed with eosinophilic granuloma for a lesion under her tongue 9 months ago by our regular vet. We initially dosed with prednisone up to 30 mg/day. The lesion responded, but would not go away. Next, we consulted an allergist, but flea control and switching diets several times provided no relief. With the guidance of an Internal medicine specialist, we dosed her with prednisone and Atopica (along with drugs for stomach upset). That failed. Eventually the internal medicine specialist suggested we try to kill the lesion will high levels of prednisone (80 mg day) which we tapered off to minimal (20 mg day) over the course of 4 - 5 months, but the lesion reappears before we get to every-other-day prednisone maintenance doses. We've also tried holistic remedies including bovine colostrum, but nothing works. At this point living with the lesion seems less life threatening than the prednisone treatment. Any advice on controlling the lesion?

Asked by Member 1148400 on Jan 5th 2013 Tagged eosinophilic, granuloma, lesion, sore, mouth, dog, malamute in Illness & Disease
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Kali earned her wings 10/21/14

I jumped on the internet to see what it is your talking about. It looks very painful. Apparently, this condition is very rare in dogs and about 75% of the cases are found in Huskies. Try posting this on the health forum on this site. There are more people there to help give advice. Try to give as much detail on the treatment you have already tried. Good Luck!

Kali earned her wings 10/21/14 answered on 1/5/13. Helpful? Yes/Helpful: No 0 Report this answer